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  1. Michael Harrop

    Doxycycline Advice

    https://humanmicrobiome.info/faq/ https://humanmicrobiome.info/probiotic-guide/ In my opinion (+ https://humanmicrobiome.info/antibiotics/), nothing but FMT will reverse that damage.
  2. Michael Harrop

    Is that IBS? Is that SIBO? Is that SIFO?

    Only your doctor can tell you if you have IBS. "SIBO" and "SIFO" are largely not real diagnoses. They're incorrect notions spread like wildfire on the internet for some reason... Perhaps they're easier for laypeople to grasp the notion of, and perhaps there are people profiting off of...
  3. Michael Harrop

    Early life antibiotics and gut microbiome

    Yes, they definitely can. There's a whole wiki page on this: https://humanmicrobiome.info/maternity/ Antibiotics at any point in life do long-term damage. Early life may be the most damaging though.
  4. Michael Harrop

    Gut microbiome and personality

    Yes. I don't think that's a valid way to go about FMT. "I'm high in X so find a donor low in X". Rather, look for a donor with an eubiotic, disease-resistant, unperturbed microbiome. People with all sorts of disorders and diseases would all benefit from the same "super-donor".
  5. Michael Harrop

    Gut microbiome and personality

    That was something I was curious and concerned about when I started out looking for a donor. Overall, FMT does not transfer personality, other than making you a better or worse version of yourself. It can certainly cause changes to "character traits", but largely only in so much as improving or...
  6. Michael Harrop

    Gut microbiome and intelligence

    Yes, I think creativity is a component of intelligence.
  7. Michael Harrop

    We’re Missing the Big Picture on the HMB

    Your only mention of antibiotics is "antibiotic/ steroid treated meats". Why is that? And no mention of breastfeeding?
  8. Michael Harrop

    Chlorine in treated drinking water

    It's possible that chlorine is having some detrimental impact. Anecdotally, our 1-in-23,000 donor was drinking unfiltered tap water until I recommended they start using a filter. And one of the ideal donors I previously found lived in a home with an RO water system. I found some mixed evidence...
  9. Michael Harrop

    Sugar and carbs intolerance

    https://humanmicrobiome.info/sibo/ https://humanmicrobiome.info/candida/ https://www.healthline.com/nutrition/candida-symptoms-treatment I'd go with "something else" -- "gut dysbiosis". Have you seen a GI doctor? I doubt they could do much for you, but most other suggestions people will give...
  10. Michael Harrop

    Soil Based Probiotics

    That soil-based warning stemmed from my personal experience with one soil-based probiotic, and some other warnings I read: https://humanmicrobiome.info/probiotics/#harmssafety I don't think you can match the impacts on cats and humans though.
  11. Michael Harrop

    Gut microbiome and personality

    https://humanmicrobiome.info/brain/?h=personality#fmt Correlation between gut microbiota and personality in adults: A cross-sectional study (2017): https://www.sciencedirect.com/science/article/pii/S0889159117305536 Gut microbiome composition and diversity are related to human personality...
  12. Michael Harrop

    Gut microbiome and intelligence

    Both. Lots of ups and downs. I have plenty of genius-IQ applicants to humanmicrobes.org. I haven't ranked them highly due to other factors such as stool type. People are welcome to use them though.
  13. Michael Harrop

    Gut microbiome and intelligence

    https://humanmicrobiome.info/brain/ I absolutely think so, and I've experienced it myself to drastic degrees. I thought I mentioned in my FMT reports that I was experiencing changes as drastic as the character in the novel "Flowers for Algernon", but I don't see it mentioned there. I found it...
  14. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    It's not generally known, but I have a hypothesis. Yet even after screening a million applicants I haven't been able to find someone that meets the requirements... Not currently. Knowledge and capabilities are too limited https://humanmicrobiome.info/testing.
  15. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    There is plenty of evidence that it does. To varying extents, yes. That is not its purpose. Depends where you get it https://humanmicrobiome.info/where-to-get-fmt. You do it again. It varies. https://humanmicrobiome.info/fmt/ Everyone should be doing that anyway. Genetics are certainly...
  16. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Do a web search. That's the strain. https://humanmicrobiome.info/probiotic-guide It can happen. Sure. https://humanmicrobiome.info/h-pylori/
  17. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1. Random luck. See https://www.humanmicrobes.org/blog 3, 4. https://humanmicrobiome.info/diet/ 5, 6. https://www.ecosia.org/search?q=how%20the%20duodenum%20works https://humanmicrobiome.info/intestinal-permeability/ You should do web searches for most of your questions.
  18. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    That's probably a decent analogy. However, a healthy swam will scatter less as well. More so different percentages, as different ones thrive in different environments. Yes. There's some here https://humanmicrobiome.info/intro/#drugs Virtually everything you ingest will have an impact on the...
  19. Michael Harrop

    Thoughts on Psyllium Husk (Metamucil) and Stool Quality

    Anything like that would vary from person to person. You just have to try it and see.
  20. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Indeed. Discussed here https://www.humanmicrobes.org/blog/half-a-million-stool-donor-applicants You lack the microbes needed to digest those foods properly. Definitely. An elimination diet is the best option. https://humanmicrobiome.info/diet/#elimination-diets I'd say no...
  21. Michael Harrop

    Suppression of infections caused by opportunistic bacteria

    The gut microbiome regulates other body site's microbiomes. https://humanmicrobiome.info/urobiome/ https://humanmicrobiome.info/systemic/ Carnivore is an elimination diet https://humanmicrobiome.info/diet/#elimination-diets and will not repopulate anything. There is. Mostly for FMT...
  22. Michael Harrop

    Suppression of infections caused by opportunistic bacteria

    You didn't mention the method that you're going to use to "double down on creating the healthiest microbiome possible".
  23. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    That is very unproven still. Those are phyla and genus, which have very limited value. https://humanmicrobiome.info/testing/ That lists some species, but that's still very limited, as is the research on them. There is a "mental health" section on the probiotics page...
  24. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I don't know about ADHD medication. I can certainly relate :) See the FAQ https://humanmicrobiome.info/faq/ Definitely. It seems to be the case for many/most people with dysbiosis, but high-quality stool donors for example are not in flux.
  25. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Mostly CFS and IBS, but many other symptoms as well, including low brain function and food intolerances. https://forum.humanmicrobiome.info/threads/my-detailed-experiences-lessons-from-13-different-fmt-donors-jun-2018.53/ Standard info. Slowly, sure. I may be biased because I run...
  26. Michael Harrop

    Michael Harrop Q&A (Nov 2023)

    An artist sent me some questions. I thought they were good questions so I took the time to answer in depth. I like this question. The vast majority of futuristic predictions/scenarios I see are completely wrong because none of them take into account that the vast majority of people alive today...
  27. Michael Harrop

    One of the responses to a 2015 review titled "Time to consider the risks of caesarean delivery for long term child health" infuriated me.

    The full response: https://www.bmj.com/content/350/bmj.h2410/rr The author of the response: Paul T-Y Ayuk Consultant obstetrician Newcastle-upon-Tyne Hospitals NHS Trust Quote: Firstly, it seems he's arguing against informed consent, and seems like he's saying that his personal preferences are...
  28. Michael Harrop

    Thoughts on Psyllium Husk (Metamucil) and Stool Quality

    I don't think this is a valid notion. It will vary from person to person. Monitor changes to your health symptoms. It's extremely rough/basic. It is not based on much. With humanmicrobes.org I'm still trying to "prove" the best type for FMT, but what is best for an FMT donor may not be the...
  29. Michael Harrop

    Any concerns about covid vaccination affecting FMT quality?

    As you said, both vaccines and the viruses they're made to protect against have the ability to impact the gut microbiome.
  30. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1. https://humanmicrobiome.info/faq. I'm pursuing FMT because I think it's the only valid option currently. 2. It was fine till 4:00. Re SIBO, see https://humanmicrobiome.info/sibo. I don't think their probiotic challenge is valid. See https://humanmicrobiome.info/probiotic-guide for more info...
  31. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Maybe other people can recommend their favorites. GI doctors won't. Naturopaths & alt-med docs might. It's not diagnosed or treated. If you pay naturopaths and alt-med doctors to tell you otherwise, then they will. There's always someone willing to take your money and tell you what you want to...
  32. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1. The authors explained it. The benefits of a microbe are not simply to produce one compound. 2. I also get fatigued when taking magnesium. It seems to be associated with its stool-softening effects. 3. There are a variety of signaling mechanisms throughout the body.
  33. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    That's a nice review, and I completely agree that restoring butyrate producers is vastly preferable to supplementing butyrate. I don't think that things like exact percentages are well-established. There are many research groups studying the Hadza, yet they're not able to replicate the benefits...
  34. Michael Harrop

    Melinda Gates (Gates Foundation) promoting antibiotics as a way to improve public health (PBS Oct 17, 2023) Melinda French Gates' Brief But Spectacular take on making birth safer for moms and babies

    She starts off talking about how she values healthy moms and babies. I couldn't agree more. This was looking promising. Then she goes on to inform us that her solution is giving antibiotics to mothers at the time of birth. This is another unfortunate example of the medical system and public...
  35. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I don't recall any few "wow" ones; nor a top 10. Just the whole body of literature in the wiki. For introductory info I would recommend the two books here, and the Frontiers review https://humanmicrobiome.info/intro/#general-articles. This article I wrote sums things up as well...
  36. Michael Harrop

    Any concerns about covid vaccination affecting FMT quality?

    FMT donor quality? There is general info about vaccines here https://humanmicrobiome.info/immune-system. I don't recall any good evidence that COVID vaccines would be an issue for FMT donors. Someone shared some links via email but they were poor quality. I think one was a retracted paper...
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