I’m new here and I’m very excited to find this exceptional resource for everything microbiome! Thank you!
I’m interested in your thoughts about using young, healthy, well-matched donors for microbiota transfer treatments from the rest of the body (besides stool) including: oral (separate multi-kingdom communities including biofilms from the oral cavity), vaginal, nasal, skin, and so forth. I know that vaginal microbiota transplants have been used successfully for bacterial vaginosis, but I can foresee a future where everything from tears and menstrual blood to volatile organic compounds from the lungs and more being used to save lives! Everything previously thought as simply waste products being used instead to reboot an older and/or weaker body. Can you imagine how wonderful it would be to see healthy young people compensated for everything they would’ve ordinarily thrown away? Ideally one would find a few excellent “mini-me’s” that would be available for donations.
My other question is, looking for the best donor, why wouldn’t it be a good idea to find the best fit possible, for example, matching blood types, sex, and possibly key genetics such as the major histocompatibility genes? (In addition to the very best screening techniques for any pathogens.)
Also, although there may not be clinical trial results available yet for the perfect protocols, if one has major inflammation caused by a variety of pathogens, why wouldn’t we try eliminating the pathogens effectively first; such as using antibiotics, anti-fungals, anti-parasitics, antivirals and/or bacteriophages as needed, to eradicate the pathogens before the transplants?
I would love to hear what your thoughts are about these questions.