Oral microbiome - Streptococcus overgrowth (test results)

Aeon

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Sep 2, 2025
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Hi, my test results (Oralis 1, shotgun metagenomics method) show overgrowth of Streptococcus species in my oral microbiome.


My test shows the Streptococcus genus at 35.3%, while the healthy average is around 20.8%.


They produce a lot of lactic acid and cause different taste because of this.


How to reduce them? I already reduced sugars in my diet, take xylitol 5x day, K12 with M18, and added a lot of green leafs vegetables to support Rothia and Nesseria with nitrates.


Mouthwashes are not an option, because they kill all, good and bad bacteria.


Streptococcus mitis: 8.0% (Normal range: 0 - 4.7%)


Streptococcus oralis: 4.5% (0.1 - 2.3%)


Streptococcus pneumoniae: 3.5% (0 - 1.2%)


Streptococcus sp. A12: 2.1% (0.09 - 1.2%)


Streptococcus sanguinis: 1.9% (0.04 - 1.2%)


Streptococcus australis: 1.8% (0.1 - 1.3%)


Streptococcus sp. Marseille-Q3533: 1.8% (0.1 - 1.7%)


Streptococcus sp. Marseille-Q6470: 1.2% (0.2 - 1.1%)


Streptococcus gwangjuense: 0.8% (0 - 0.3%)


Streptococcus toyakuensis: 0.7% (0 - 0.4%)


Streptococcus sp. D7B5: 0.7% (0 - 0.1%)


Streptococcus pseudopneumoniae: 0.6% (0 - 0.2%)


Streptococcus sp. 116-D4: 0.5% (0 - 0.2%)


Streptococcus sp. oral taxon 064: 0.5% (0 - 0.1%)


Streptococcus sp. NPS 308: 0.5% (0.003 - 0.1%)


Streptococcus agalactiae: 0.2% (0 - 0.09%)


Streptococcus sp. 1643: 0.2% (0.003 - 0.08%)

Thank you.
 
Thanks for sharing this test here! I didn't know such a thing existed. Aside from reducing sugars and simple carbohydrates, or trying to get bacteria from a healthy donor, I don't know of a way to reduce Streptococcus. Many probiotics contain their own species of Streptococcus, which are probably relatively more benign as far as Streptococcus go, but it's still adding more of something similar. Even Lactobacillus is very close to Streptococcus--so again it's kind of more of the same group, even if it's less-bad species within that group.

There's no probiotic on the market that contains anything even remotely like Rothia or Neisseria. You MAY want to try a Bifidobacterium-only probiotic like ProBiota if you haven't already done so, only because they are evolutionarily far removed from Streptococcus, and though they fill a similar niche of carbohydrate fermentation they do it in a different way (using something called the "bifid shunt" and producing mostly acetate, not lactate).

Out of curiosity, do you have a substantial amount of species like Rothia and Neisseria, just at a slightly lower percent than normal, or are the levels of these almost undetectable?
 
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Thank you for your kindness and willingess to help.

Yesterday I bought this:
www.amazon.co.uk/dp/B0DZX4CR63

Is it a good idea in the discussed context to also take xylitol and arginine powder a few times a day?

I do not think that a donation (except kissing, and some experimental, closed trials starting now in USA) is available.
  • Rothia mucilaginosa: 2.7% (normal range 3.9–21.0%)
  • Rothia aeria: 1.0% (normal range 0–0.7%)
  • Rothia dentocariosa: 1.2% (normal range 0–1.7%)

  • Neisseria subflava: 8.8% (normal range 1.1–14.9%)
  • Neisseria cinerea: 0.07% (normal range 0–0.7%)
  • Neisseria polysaccharea: 0.05% (normal range 0–0.06%)
  • Neisseria gonorrhoeae: 0.1% (normal range 0–0.2%)
  • Neisseria bacilliformis: 0.02% (normal range 0–0.1%)
 
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