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  1. Michael Harrop

    Fermented foods and gut microbiome

    https://humanmicrobiome.info/probiotic-guide - they can be, but they're largely overhyped, limited, and can have detriments. It's quite difficult (and not fully studied) to determine and weigh all the pros & cons. And as with most things, it varies from person to person, so you'll have to...
  2. Michael Harrop

    Enhancing I figured out my gut biome issue, might explain why FMT's don't take: B12 and folate deficiencies creating an environment that hinders the success of FMT

    What is the reasoning behind "might explain why FMT's don't take"?
  3. Michael Harrop

    Causation Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study (Jun 2025)

    https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03789-x
  4. Michael Harrop

    FMT Fecal transplants: Study is a 'wake-up call' for the field as researchers identify unintended consequences. (Jun 2025, mice) Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects

    https://www.dw.com/en/fecal-transplants-study-is-a-wake-up-call-for-the-field/a-72817699 https://www.the-independent.com/news/health/fecal-transplants-consequences-research-us-b2765279.html...
  5. Michael Harrop

    FMT Public knowledge, awareness and perception of gut microbiome and faecal microbiota transplantation in Singapore: a survey study (Jun 2025, n=1831) "33% had heard of the gut microbiome, 92% had consumed probiotics, 85% had not heard of FMT, 72% would consider FMT to treat C. diff"

    https://journals.lww.com/smj/fulltext/9900/public_knowledge,_awareness_and_perception_of_gut.196.aspx
  6. Michael Harrop

    Article Kennedy Says ‘Charlatans’ Are No Reason to Block Unproven Stem Cell Treatments. The U.S. health secretary said people should have access to experimental therapies including unregulated uses of stem cells. But some methods have resulted in blindness, tumors and other injuries. (Jun 2025)

    https://www.nytimes.com/2025/06/05/health/kennedy-stem-cells-experimental-treatments.html
  7. Michael Harrop

    Antibiotics Human antibiotics are polluting Earth's rivers, helping bacteria develop the resistance they need to then kill humans (Apr 2025) Antibiotics in the global river system arising from human consumption

    https://www.earth.com/news/earth-rivers-are-highly-saturated-with-human-antibiotics-helping-bacteria-develop-resistance/ https://academic.oup.com/pnasnexus/article/4/4/pgaf096/8113371
  8. Michael Harrop

    Oral Causal association between oral microbiota and oral cancer: a mendelian randomization study (Jun 2025) "Our findings suggest that Prevotella and Veillonella were causally linked to OC"

    https://www.nature.com/articles/s41598-025-05553-5
  9. Michael Harrop

    FMT Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice (Jun 2025) "human-derived microbiota was less effective in clearing C. difficile compared to a mouse-derived microbiota"

    https://journals.asm.org/doi/10.1128/mbio.01108-25
  10. Michael Harrop

    Article Over the last several decades, the FDA has allowed pharma companies to sell hundreds of drugs to patients without adequate evidence that they work and, in many cases, with clear signs that they pose a risk of serious harm (Jun 2025)

    https://jacobin.com/2025/06/fda-approval-drugs-effectiveness-risk/
  11. Michael Harrop

    FMT Donor composition and fiber promote strain engraftment in a randomized controlled trial of fecal microbiota transplant for ulcerative colitis (Jun 2025, n=27) "the effect depends on the specific donor microbiota and not on patient fiber use"

    https://www.cell.com/med/abstract/S2666-6340(25)00134-5
  12. Michael Harrop

    FMT Donor-derived microbial engraftment and gut microbiota shifts associated with weight loss following fecal microbiota transplantation (Jun 2025, n=23) "52% achieved weight loss of more than 5% from baseline. Average weight loss of 8kg/18lbs"

    https://journals.asm.org/doi/10.1128/aem.00120-25 Chinese study. 52% achieved weight loss of more than 5% from baseline. Average weight loss of 8kg (18 lbs). Nonresponders lost 3kg. Contrary to some other studies, they found engraftment to correlate with success. Donors: But they couldn't...
  13. Michael Harrop

    Microbioma Review of Microbioma.org. (2022)

    It appears that they just purchased a "review" from Mark Rogers on a new "Crypto Security News & Innovation" website called Thodex, to try to drown out other search results exposing them. EDIT: Ah, of course a negative "Human Microbes scam" page was purchased from Thodex too... Which is full of...
  14. Michael Harrop

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    You need to read the other information on this forum and get involved in efforts to make those trials available from safe and effective donors. 1. That's for probiotics, so not surprising at all. 2. You'd have to do a search. 4. Any new info I see gets added to the probiotic guide and wiki...
  15. Michael Harrop

    Video PFAS: How This Corporation Secretly Poisoned Our Food, Water, and Blood | More Perfect Union, Jun 2025

    The video covers the known harms and history of PFAS, and then covers this Trump administration's regulatory capture that will prevent anything from being done. Very depressing. https://www.youtube.com/watch?v=Y0lsLnXX4U8
  16. Michael Harrop

    Fungi Gut fungi in very-low-birthweight infants modulate oxygen-induced lung damage (Jan 2025) The fungal microbiota modulate neonatal oxygen-induced lung injury

    https://www.eurekalert.org/news-releases/1086041 https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02032-x
  17. Michael Harrop

    Origins The human milk microbiome is minimally associated with breastfeeding practices (Jun 2025, n=56)

    https://www.nature.com/articles/s41598-025-03907-7
  18. Michael Harrop

    Study Millions of US children have parents with substance use disorder, and the consequences are staggering (May 2025) US Children Living With a Parent With Substance Use Disorder

    https://theconversation.com/millions-of-us-children-have-parents-with-substance-use-disorder-and-the-consequences-are-staggering-new-research-256979 https://jamanetwork.com/journals/jamapediatrics/article-abstract/2833575
  19. Michael Harrop

    FMT Fecal microbiota transplant is associated with resolution of recurrent urinary tract infection (May 2025) "Of 11 patients who had rUTI in the two years preceding FMT, no patient had rUTI over the 2-year follow-up period after FMT"

    https://www.goldjournal.net/article/S0090-4295(25)00515-1/fulltext
  20. Michael Harrop

    Donors Doubts about supposed donor compatibility/matching, signaling, and microbiota depletion

    Engraftment. There are a few threads on donor matching: https://forum.humanmicrobiome.info/forums/fecal-microbiota-transplant-fmt/?prefix_id=66 Here's a summary: https://forum.humanmicrobiome.info/threads/does-stool-donor-sex-and-age-matter-are-there-differences-in-receiving.416/post-1029...
  21. Michael Harrop

    Article White House releases RFK Jr.-led report on chronic disease (May 2025) The MAHA Report, Make Our Children Healthy Again Assessment

    RFK Jr.’s MAHA Report Is ‘Rife With Errors’ — Including at Least Seven Fake Sources (May 29, 2025) https://www.mediaite.com/politics/rfk-jr-s-maha-report-is-rife-with-errors-including-at-least-seven-fake-sources/ The MAHA Report Cites Studies That Don’t Exist. The Trump administration’s “Make...
  22. Michael Harrop

    Article Toxic pesticide (glyphosate) levels found in tampons 40 times higher than legal limit for water (May 2025)

    https://www.theguardian.com/environment/2025/may/28/toxic-pesticide-levels-found-in-tampons-40-times-higher-than-legal-limit-for-water https://www.pan-uk.org/period-products/ First heavy metals, now pesticides.
  23. Michael Harrop

    Microbioma Today I received a letter from Microbioma that he will most likely sue me

    Scammers are not going to take you to court... Police and judges are some of the only people they can't fool. These guys prey on poorly informed people who lack the intelligence to take action after they get scammed. They are still in business because they know how to keep their target...
  24. Michael Harrop

    Early development Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment (May 2025, mice) "finding suggests that the host early in life has mechanisms to select microbes appropriate for age"

    https://www.nature.com/articles/s41598-025-03661-w Given that dysbiosis generally increases with age, to me, it sounds more like the mucosa gets worse at resisting problematic microbes as age increases.
  25. Michael Harrop

    Oral Swapping spit with your spouse may spread anxiety and depression (Apr 2025, 536 couples) Oral Microbiota Transmission Partially Mediates Depression and Anxiety in Newlywed Couples

    https://newatlas.com/mental-health/oral-microbiome-spouse-anxiety-and-depression/ https://www.xiahepublishing.com/2472-0712/ERHM-2025-00013
  26. Michael Harrop

    Enhancing Antifreeze in stool/FMT capsules, glycerol vs maltodextrin, -80 (medical freezer) vs -20 (home freezer)

    Closed access: Evaluation of the effects of different formulations of protectants on the preservation of the microbiota in fecal microbiota transplantation (May 2025) https://link.springer.com/article/10.1007/s10123-025-00663-6
  27. Michael Harrop

    FMT Bidirectional modulation of Alzheimer’s disease via gut microbiota: rescue by fecal transplantation from healthy donors and aggravation by colitis-associated dysbiosis (May 2025) "neuroinflammation occurred independently of gut barrier disruption, implicating circulating microbial metabolites"

    https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1593854/full
  28. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    They released their 100-day assessment of the chronic disease crisis today: White House releases RFK Jr.-led report on chronic disease (May 2025) The MAHA Report, Make Our Children Healthy Again Assessment It's a good report, but light on the main driver -- the gut microbiome.
  29. Michael Harrop

    Article White House releases RFK Jr.-led report on chronic disease (May 2025) The MAHA Report, Make Our Children Healthy Again Assessment

    https://www.whitehouse.gov/maha/ https://www.hhs.gov/press-room/maha-commission-childhood-chronic-disease-root-causes.html The 70-page report: https://www.whitehouse.gov/wp-content/uploads/2025/05/WH-The-MAHA-Report-Assessment.pdf Articles...
  30. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    An interesting PBS piece on Casey Means, from May 21, 2025: https://www.pbs.org/newshour/show/the-background-and-career-of-casey-means-trumps-pick-for-surgeon-general Her nomination is subject to Senate confirmation, which means I could probably spot her and talk to her. I'm not too sure what...
  31. Michael Harrop

    Study Industry study sponsorship and conflicts of interest on the effect of unprocessed red meat on cardiovascular disease risk: a systematic review of clinical trials (May 2025) "Most studies without conflicts of interest suggested an unfavorable effect"

    https://www.sciencedirect.com/science/article/abs/pii/S0002916525001261
  32. Michael Harrop

    Advocacy NIH National Advisory Neurological Disorders and Stroke Council (NANDSC) ME/CFS Research Roadmap Working Group - letter re finalized roadmap

    I attended the MEAction Millions Missing protest outside the Capitol building on May 12, 2025. https://www.meactions.org/millionsmissing25 I contacted the MEAction directors two weeks prior, then spoke to them and the crowd during the protest, and then wrote to them again afterward. I explained...
  33. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    The limits of the "one-man-army": I talked to a Senator, and he was receptive. He had me talk to his staff about it; one of whom was a doctor. I had sent them the info twice already (via website, then direct email). I sent it to them a 3rd time prior to the meeting. During the meeting, I...
  34. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    RFK Senate appropriations hearing: https://www.appropriations.senate.gov/hearings/a-review-of-the-presidents-fiscal-year-2026-budget-request-for-the-department-of-health-and-human-services Another RFK hearing where he mentions the microbiome. So he seems to be on board. I've been trying to...
  35. Michael Harrop

    Donors Thoughts on HumanMicrobes donor problem

    I'm aware. Which is why I said they've been doing a lot of good stuff. That's what I meant. The donors I find have always been available to everyone. And I wasn't speaking about funding, I said "their funders", IE: the patient community. A lot of the most valuable help would be non-monetary...
  36. Michael Harrop

    FMT Therapeutic efficacy of fecal microbiota transplantation in severe food intolerance: a case report (May 2025, 7-year-old autistic child)

    https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1594022/full They have pictures of the patient's stool as it progresses https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1594022/full#F1. This is the first time I can recall seeing that. I...
  37. Michael Harrop

    Procedure Getting blood and stool testing for an FMT donor

    This is covered in the wiki: https://humanmicrobiome.info/fmt/#screening I've done both.
  38. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    I don't agree with "complete deregulation". I've opposed it since the beginning, and advocated for better regulation focused on donor quality. Complete deregulation would result in people going to doctors (or even various scammers), expecting a safe and effective treatment, receiving FMT from...
  39. Michael Harrop

    Questions regarding friend's bacteria/gut health results

    You're in for a rough time then. You were given pretty simple information. If you're unable to understand something that simple, you shouldn't be trying to do anything of this nature on your own. At best, you'll waste a lot of money, or worse, you'll harm yourself. Stay away from Facebook &...
  40. Michael Harrop

    Questions regarding friend's bacteria/gut health results

    Your friend gave you good advice. No one said this wasn't the right place, and your question did not go unanswered. You need to put in some minimal effort to read and understand the information provided to you. What you are doing is seeking information that supports your preconceptions, which...
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