Worse after FMT

thefmtdude

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Oct 22, 2025
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Hi, 6 days ago I did FMT through colonoscopy due to my refractory IBS-D. Unfortunately, my poop is worse after FMT. Is microbiome after FMT stable or temporary?


I feel like I gained diarrhea from someone else. I need much more effort to feel relief than before. I prefer my previous D state than post-FMT D state
 
In general, it seems like the only way to recover from a bad FMT is to do FMT from a better donor.

Where did you get the FMT? From a hospital, using their donor? They did it for IBS? Was it part of a clinical trial?
 
Hospital, their screened donor. It was a medical experiment. Anyway, I don't want to repeat it. Will I return to my baseline?
 
Hi, 6 days ago I did FMT through colonoscopy due to my refractory IBS-D. Unfortunately, my poop is worse after FMT. Is microbiome after FMT stable or temporary?


I feel like I gained diarrhea from someone else. I need much more effort to feel relief than before. I prefer my previous D state than post-FMT D state
I had IBS previous to a severe case of C-diff. But since recovering from the C-diff with the help of taking VOWST (after 3 relapses) I learned about making my own milk kefir. It has helped me tremendously with my IBS. I really don't have the symptoms of IBS since drinking a glass of homemade kefir daily. Check it out on You Tube - short videos and it's practically effortless to make.
 
Hi, I'm also going to participate in a faecal transplant trial. Like you, I have refractory irritable bowel syndrome. Could you tell me which country you participated in?
I know about the risks of poor donor selection due to low quality, but I'm incapable of doing it myself and handling it. I do have someone willing to give me enemas, but not to handle the faeces. I can't find anyone around me who is healthy. A friend offered to donate her faeces, but she often has recurrent cystitis and a little abdominal bloating after certain meals, which suggests some level of dysbiosis. She is the healthiest person I know, but she is not what we need; we need healthy and robust microbiota.
On the one hand, I am afraid of getting worse, but on the other, I feel like I am at the end of my rope and I have no more will to fight.

Michael, I didn't know where to mention this, but I'm not sure how true the idea of athletes as healthy people really is. I say this because I know athletes in my circle who lead seemingly normal, healthy, athletic lives and have a very controlled diet, but despite this, they occasionally and sometimes frequently use certain drugs. No athlete will admit to using certain substances. This is my experience with people I know, but I think it may be more common than people think, even if it's not the case in all instances.

I apologise for any incorrect translation, English is not my first language.
 
Previous to my c-diff which was treated successfully with VOWST, I had Irritable Bowel Syndrome - I have been making my own milk kefir and drinking a glass every day before bed. I am symptom free of IBS and can function normally. I don't know what the difference is by "refractory I B S, " but do a search on You Tube about making your own milk kefir and read the testimonials of people who have had positive results.
 
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