The gut microbiome, COVID-19, and long COVID [collection of studies]

Michael Harrop

Active member
Jul 6, 2023
I saw news about "Chairman Bernie Sanders Releases Long COVID Moonshot Legislative Proposal", and I wanted to make a post listing the research I've seen on this.

From what I see in their proposal, they're allocating 1 billion dollars into general research. I find this very frustrating given that FMT (fecal microbiota transplants) is almost certainly a currently-existing treatment/cure, yet it will continue to be ignored and all the focus and funding will be put elsewhere, as is the norm.

Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms (2023)

Long Covid ‘brain fog’ may be due to leaky blood-brain barrier (Feb 2024) Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment.

Metagenomic assessment of gut microbial communities and risk of severe COVID-19 (July 2023, n=127). "the gut microbiome differentiates individuals with a more severe disease course after infection with COVID-19"

A group of scientists suggest some cases of long Covid might be caused by remnants of the coronavirus lingering in the gut. (Oct 2023) Serotonin reduction in post-acute sequelae of viral infection.

"Two patients had COVID-19-related pneumonia, and FMT cured both from CDI and COVID-19" (Sep 2020)

Poop Transplants Have Been Linked to Improved COVID-19 in Two Patients in Poland (Jul 2021) Rapid resolution of COVID-19 after faecal microbiota transplantation.

Intestinal Flora as a Potential Strategy to Fight SARS-CoV-2 Infection (review, 2020)

Gut reaction: How the gut microbiome may influence the severity of COVID-19 (Jun 2020)

Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (Jan 2021, n=100)

Gut Microbes Could Predict How Seriously Ill a COVID-19 Patient Might Get. (2021, n=1657) Gut microbiota, inflammation, and molecular signatures of host response to infection.

Fecal microbiota transplantation for COVID-19; a potential emerging treatment strategy (Dec 2020)

Gut Microbiota in Covid-19: An unrecognised player? (review, 2020)

The gut microbiome: an under-recognised contributor to the COVID-19 pandemic? (review, 2020)

A healthy microbiome builds a strong immune system that could help defeat COVID-19 - The intestinal and oral microbiomes are robust predictors of covid-19 severity the main predictor of covid-19-related fatality (Jan 2021).

Human gut microbiota and its metabolites impact immune responses in COVID-19 and its complications (Sep 2022, N=224)


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