Michael Harrop
Active member
I saw news about "Chairman Bernie Sanders Releases Long COVID Moonshot Legislative Proposal", and I wanted to make a post listing the research I've seen on this.
From what I see in their proposal, they're allocating 1 billion dollars into general research. I find this very frustrating given that FMT (fecal microbiota transplants) is almost certainly a currently-existing treatment/cure, yet it will continue to be ignored and all the focus and funding will be put elsewhere, as is the norm.
Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms (2023) https://www.tandfonline.com/doi/full/10.1080/19490976.2023.2249146
Long Covid ‘brain fog’ may be due to leaky blood-brain barrier (Feb 2024) Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment.
Metagenomic assessment of gut microbial communities and risk of severe COVID-19 (July 2023, n=127). "the gut microbiome differentiates individuals with a more severe disease course after infection with COVID-19"
A group of scientists suggest some cases of long Covid might be caused by remnants of the coronavirus lingering in the gut. (Oct 2023) Serotonin reduction in post-acute sequelae of viral infection.
"Two patients had COVID-19-related pneumonia, and FMT cured both from CDI and COVID-19" (Sep 2020) https://www.dldjournalonline.com/article/S1590-8658(20)30474-6/fulltext
Poop Transplants Have Been Linked to Improved COVID-19 in Two Patients in Poland (Jul 2021) https://www.sciencealert.com/two-people-in-poland-had-poo-transplants-and-somehow-their-covid-symptoms-got-better Rapid resolution of COVID-19 after faecal microbiota transplantation.
Intestinal Flora as a Potential Strategy to Fight SARS-CoV-2 Infection (review, 2020) https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.01388/full
Gut reaction: How the gut microbiome may influence the severity of COVID-19 (Jun 2020) https://theconversation.com/gut-reaction-how-the-gut-microbiome-may-influence-the-severity-of-covid-19-139094
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (Jan 2021, n=100) https://www.eurekalert.org/news-releases/866884
Gut Microbes Could Predict How Seriously Ill a COVID-19 Patient Might Get. (2021, n=1657) https://www.newsweek.com/gut-microbes-could-predict-how-seriously-ill-covid-19-patient-might-get-preliminary-study-suggests-1500568. Gut microbiota, inflammation, and molecular signatures of host response to infection.
Fecal microbiota transplantation for COVID-19; a potential emerging treatment strategy (Dec 2020) https://www.sciencedirect.com/science/article/pii/S0306987720333673
Gut Microbiota in Covid-19: An unrecognised player? (review, 2020) https://www.frontiersin.org/articles/10.3389/fcimb.2020.576551/full
The gut microbiome: an under-recognised contributor to the COVID-19 pandemic? (review, 2020) https://journals.sagepub.com/doi/10.1177/1756284820974914
A healthy microbiome builds a strong immune system that could help defeat COVID-19 https://theconversation.com/a-healthy-microbiome-builds-a-strong-immune-system-that-could-help-defeat-covid-19-145668 - The intestinal and oral microbiomes are robust predictors of covid-19 severity the main predictor of covid-19-related fatality (Jan 2021).
Human gut microbiota and its metabolites impact immune responses in COVID-19 and its complications (Sep 2022, N=224) https://www.sciencedirect.com/science/article/pii/S0016508522010812
More: https://microbiomedigest.com/2021/06/21/microbiome-and-covid19-some-research-highlights/
Also relevant:
From what I see in their proposal, they're allocating 1 billion dollars into general research. I find this very frustrating given that FMT (fecal microbiota transplants) is almost certainly a currently-existing treatment/cure, yet it will continue to be ignored and all the focus and funding will be put elsewhere, as is the norm.
Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms (2023) https://www.tandfonline.com/doi/full/10.1080/19490976.2023.2249146
Long Covid ‘brain fog’ may be due to leaky blood-brain barrier (Feb 2024) Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment.
Metagenomic assessment of gut microbial communities and risk of severe COVID-19 (July 2023, n=127). "the gut microbiome differentiates individuals with a more severe disease course after infection with COVID-19"
A group of scientists suggest some cases of long Covid might be caused by remnants of the coronavirus lingering in the gut. (Oct 2023) Serotonin reduction in post-acute sequelae of viral infection.
"Two patients had COVID-19-related pneumonia, and FMT cured both from CDI and COVID-19" (Sep 2020) https://www.dldjournalonline.com/article/S1590-8658(20)30474-6/fulltext
Poop Transplants Have Been Linked to Improved COVID-19 in Two Patients in Poland (Jul 2021) https://www.sciencealert.com/two-people-in-poland-had-poo-transplants-and-somehow-their-covid-symptoms-got-better Rapid resolution of COVID-19 after faecal microbiota transplantation.
Intestinal Flora as a Potential Strategy to Fight SARS-CoV-2 Infection (review, 2020) https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.01388/full
Gut reaction: How the gut microbiome may influence the severity of COVID-19 (Jun 2020) https://theconversation.com/gut-reaction-how-the-gut-microbiome-may-influence-the-severity-of-covid-19-139094
Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (Jan 2021, n=100) https://www.eurekalert.org/news-releases/866884
Gut Microbes Could Predict How Seriously Ill a COVID-19 Patient Might Get. (2021, n=1657) https://www.newsweek.com/gut-microbes-could-predict-how-seriously-ill-covid-19-patient-might-get-preliminary-study-suggests-1500568. Gut microbiota, inflammation, and molecular signatures of host response to infection.
Fecal microbiota transplantation for COVID-19; a potential emerging treatment strategy (Dec 2020) https://www.sciencedirect.com/science/article/pii/S0306987720333673
Gut Microbiota in Covid-19: An unrecognised player? (review, 2020) https://www.frontiersin.org/articles/10.3389/fcimb.2020.576551/full
The gut microbiome: an under-recognised contributor to the COVID-19 pandemic? (review, 2020) https://journals.sagepub.com/doi/10.1177/1756284820974914
A healthy microbiome builds a strong immune system that could help defeat COVID-19 https://theconversation.com/a-healthy-microbiome-builds-a-strong-immune-system-that-could-help-defeat-covid-19-145668 - The intestinal and oral microbiomes are robust predictors of covid-19 severity the main predictor of covid-19-related fatality (Jan 2021).
Human gut microbiota and its metabolites impact immune responses in COVID-19 and its complications (Sep 2022, N=224) https://www.sciencedirect.com/science/article/pii/S0016508522010812
More: https://microbiomedigest.com/2021/06/21/microbiome-and-covid19-some-research-highlights/
Also relevant: