Stool donor with family history of colon cancer Donors

[andyandy]

Hello Everyone,

I'm new to the forum and to FMT, this will be my first attempt. Looking to do it DIY with poop donation from trusted friends/community.

One of my best donors meets all criteria, except some scant lifetime antibiotic use and anxiety that isn't "clinical", and she has a family history of colon cancer: one uncle affected with onset after 40. My donor is 28, so my thought is that it's less of a concern than if they were a bit older.

Can anyone link me to any literature about FMT and colon cancer risk? The question I would like answered is: what is the basis for concern, is it that one might actually transplant cancerous cells, or is it that one would transplant a biome that supports the development of cancer?

Also, literature or educated remarks on the general relevance of family history to donor selection are welcome as well.

Thanks for reading,
Andy

 

[Michael Harrop]

meets all criteria

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What criteria?

Can anyone link me to any literature about FMT and colon cancer risk?

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https://humanmicrobiome.info/cancer/

You can see there is plenty of basis for concern that you may "transplant a biome that supports the development of cancer".

Also, literature or educated remarks on the general relevance of family history to donor selection are welcome as well.

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It's largely unknown. FMT is all about risk vs reward, and family history is an added risk.

 

[EpilepsyFMTcure]

I'd also add the potential for hormonal disturbance that can happen when transplanting from female to male or male to female. I know there's conflicting research on this but in my own hunt for FMT transplant donors, this is something I would seriously consider as a potential variable of concern.