Post-FMT weight gain after DF6 from Gezonde Darmflora Gezonde Darmflora 

Founded by Marco Kleijn, Netherlands

minkstollen

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I got capsule FMT from DF6 at https://gezonde-darmflora.nl/

I was trying to cure a decades-long battle with methane dominant SIBO and only checked that the bacteria I have overgrown were not present and that diversity was decent...I did not check F/B ratio.

Unfortunately, even if this was the real donor, donors' BMIs can be upwards of 29. My own weight at the time of FMT was 105. I am 5'8 and an avid runner. One year later and I am 130. I track calories and have changed nothing except for potentially walking and biking even more than before due to a move to a city.

My only guess other than some ineffable metabolic change to match the donor is that the F/B ratio inverted. I once had a low F/B ratio and now my fermicutes are dominating my microbiome.

I am wondering 1. if anyone else received from this donor and if so, if they have experienced the same and 2. from any donor, if anyone has identified a way to reverse post-FMT unexplained weight gain?

Please include all of the following information to make your report as useful as possible. Reports missing this info may be removed.
  • Conditions being treated? SIBO constipation type
  • Starting health (1-10)? 3
  • Ending health (1-10)? 3
  • What detriments did you experience? weight gain, worsened constipation
  • What benefits did you experience? estrogen increased (I was on HRT before)
  • Have you used other donors? How does this donor compare? NA
  • Number of FMTs over length of time? 1
  • Routes: upper, lower, both? upper
  • Fresh or Frozen? Antifreeze? frozen
  • Your stool characteristics before and after? worse
  • Your diet before, during, and after? exactly the same. whole foods, lower carb, 1400 calories
  • Supplements & medications you are/were taking?
 
FMT Clinics
  1. I included all required info
I only checked that the bacteria I have overgrown were not present and that diversity was decent...I did not check F/B ratio.

My only guess other than some ineffable metabolic change to match the donor is that the F/B ratio inverted. I once had a low F/B ratio and now my fermicutes are dominating my microbiome.
That's not a valid approach. Review the wiki: https://humanmicrobiome.info/testing/

if anyone has identified a way to reverse post-FMT unexplained weight gain?
FMT from a better donor is practically the only option. This is why the wiki urges extreme caution and warns about this particular source as well: https://humanmicrobiome.info/where-to-get-fmt/
 
What do you mean by approach? I am not proposing anything; I am asking if anyone knows a solution. I am wary of another FMT.
I am aware of this now. I was not at the time--I was desperate because I needed treatment for something else and they were unable to treat me with SIBO/IBS in the picture.
 
What do you mean by approach? I am not proposing anything; I am asking if anyone knows a solution. I am wary of another FMT.
I am aware of this now. I was not at the time--I was desperate because I needed treatment for something else and they were unable to treat me with SIBO/IBS in the picture.
Once you do FMT from a harmful donor, there is no other “definitive” solution but to try to find a better donor that can correct the damage. In your position, your options are:

  1. Find a higher-quality donor on your own. Considering you went for GD, it’s highly unlikely you personally know someone like that. But considering your athletic background, maybe you can try screening a friend. Refer to the wiki https://humanmicrobiome.info/fmt/#screening on resources to do this.
  2. Risk it by trying another GD donor.
  3. Manage the negative effects through the lesser interventions like diet, supplements, antibiotics, probiotics, medications.
 
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