Is there any chance double layered crapsules don't open at all and pass through whole? Procedure

[john silver]

hello. I don't consider myself to be knowledgeable much about the intestines and microbiome, I've a friend who has gut inflammation and many other symptoms thought to be resulting from severe microbiome dysbiosis, like severe dryness, sleep issues, and bad quality stool, etcetra, anyway, I know it's better to ask a doctor about this but I wanted to ask here first, for them, before they can take crapsules, so, their stomach is 10/10, nothing wrong there, but because of the severe dysbiosis, could the double layered vegan crapsules somehow not dissolve in the small and/or large intestines and get outta the system without getting any of the good bacteria? how much do they dissolve by the stomach's acid and how much by the intestines enzymes (or any other mechanism by the intestine)? I'm sure the dysbiosis greatly affects things, but idk to what extent, just assume the intestines are in the worst shape ever and answer accordingly if you've the relevant knowledge. in the case that yes, the crapsules could get out of the system untouched, would taking digestive enzymes help them dissove in the intestines? or would it actually harm the bacteria instead?

 

[Michael Harrop]

It depends on what exact capsules are used. With Human Microbes, we use vegan delayed-release capsules. Gelatin capsules are also common and occasionally used. You can do tests yourself by placing them in various liquids. They expand, soften, and break down within 1 hour usually. No acids or enzymes are needed, just water. So I think it's extremely unlikely that these could make it through the small intestine without breaking down and releasing their contents. Typically, you need special coatings to do that.

 

[john silver]

very helpful answer, thanks for your support