FMT preparation beforehand? Colon cleanse, bowel prep, fasting. When dealing with an irregular donor. Procedure

[YepSerious]

I intend to conduct an FMT with my toddler's stool. I've been told I should have a totally empty colon, ideally doing something like a Miralax colonoscopy prep. Unfortunately, my toddler isn't regular. Sometimes he goes daily, sometimes once every three days. And the colonoscopy prep has some pretty precise timing.

I'm already underweight and have two young ones, so potentially fasting 2-3 days while I wait for him to poop isn't my first choice... Any ideas for other options? I could potentially give him some prunes (or Miralax) to help encourage a bowel movement (or would that disrupt the quality of his sample)? Or is there another method that might achieve similar results for me, but could happen faster? Advice welcome! Thanks very much for your time!

 

[Michael Harrop]

or would that disrupt the quality of his sample

Click to shrink...

Most likely, yes.

The wiki has a section on FMT prep: https://humanmicrobiome.info/fmt/#before-the-procedure

I've done countless FMTs from 13+ donors and I don't do any prep since I haven't found it to be needed or useful.

 

[YepSerious]

Interesting. I recently did a consultation with Davide Patti, a microbiome researcher in Barcelona (see an outdated video of his here). He said he's worked with 50+ people to do them, and, at least at present, this is what he believes to be necessary for greatest effect. But I suppose it will be much easier (and I won't have much to lose) if I don't do the prep...