Akkermansia & Faecalibacterium prausnitzii paired with HMO's. Critique this.

[Sift0593]

On the one hand, HMO's have good evidence:
https://www.mdpi.com/2227-9067/8/9/804

However, Akkermansia as a probiotic, isn't well studied AFAIK. A high gut population may be good, but it doesn't necessarily follow that we can directly put Akkermansia into the gut via a probiotic and get improvements:
https://doi.org/10.1080/10408398.2018.1517725
https://doi.org/10.1016/j.jff.2017.03.045

So when I saw this, I was skeptical:
https://layerorigin.com/blogs/blog-layer-origin-nutrition/are-you-ready-for-the-next-generation-probiotic-experience-introducing-our-all-new-akkermansia-product

But what are your thoughts?

 

[smallish]

I had non-detect Akkermansia on numerous gut reports from the past. I took Pendulum Akkermansia and used HMOs and a high-fiber diet and now have good levels. I have not tested again for several months so I do not know how good staying power will be and I've also had to discontinue a lot of resistant starch, HMOs, etc. due to other gut issues so that may be detrimental to the Akkermansia. My prausnitzii, however, remains low but I wasn't able to supplement that one. I had it as a commensal but it didn't seem to benefit from the HMOs.