Search results for query: *

Forum search Google search

  1. Michael Harrop

    Antibiotics Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors (May 2025)

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1589704/full A really interesting and well-done study of all the different ways antibiotics negatively impact the gut microbiome, beyond basic measurements like diversity and composition.
  2. Michael Harrop

    FMT Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis (May 2025, n=96) FMT from humans to mice confirmed the cognitive benefits were microbiota-dependent

    https://gut.bmj.com/content/early/2025/05/07/gutjnl-2025-335353
  3. Michael Harrop

    Causation Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice—An unbiased functional study (Feb 2025)

    https://medicalxpress.com/news/2025-05-twin-bacteria-small-intestine-play.html https://www.pnas.org/doi/10.1073/pnas.2419689122
  4. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Looks like another win for us: Trump Withdraws Surgeon General Nomination and Announces New Choice. The president said on social media that he would nominate Dr. Casey Means, confirming that he had withdrawn the nomination of Dr. Janette Nesheiwat, his first pick, a former Fox News contributor...
  5. Michael Harrop

    Causation Certain bacteria in breast tumour environments may fuel cancer spread (Feb 2025, mice) Identification of intratumoral bacteria that enhance breast tumor metastasis

    https://www.med.ubc.ca/news/certain-bacteria-in-breast-tumour-environments-may-fuel-cancer-spread/ https://journals.asm.org/doi/full/10.1128/mbio.03595-24
  6. Michael Harrop

    Article Consumer Reports warns of lead in popular gluten substitute. Cassava Flour, Chips, Bread, and More (May 2025)

    https://www.oregonlive.com/retail/2025/05/consumer-reports-warns-of-lead-in-popular-gluten-substitute.html https://www.consumerreports.org/health/food-contaminants/cassava-flour-chips-bread-more-contain-high-levels-of-lead-a7817220954/ Petition: Get toxic lead out of cassava products...
  7. Michael Harrop

    Probiotics Developing a probiotic cocktail that may help ward off dementia (Jan 2025) Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail. "Underlying mechanisms may differ depending on sex"

    https://medicalxpress.com/news/2025-05-probiotic-cocktail-ward-dementia.html https://www.nature.com/articles/s41598-024-84780-8
  8. Michael Harrop

    Early development In utero human intestine contains maternally derived bacterial metabolites (May 2025, n=21)

    https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02110-0
  9. Michael Harrop

    Study Heart disease deaths worldwide linked to chemical widely used in plastics (Apr 2025) Phthalate exposure from plastics and cardiovascular disease: global estimates of attributable mortality and years life lost

    https://medicalxpress.com/news/2025-04-heart-disease-deaths-worldwide-linked.html https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00174-4/fulltext
  10. Michael Harrop

    Article New NIH office to reduce use of animals in research, shuts down final beagle lab. Agency plans to promote alternative methods and address “bias” toward animal studies in grant review (Apr 2025)

    https://www.science.org/content/article/new-nih-office-reduce-use-animals-research https://www.shorenewsnetwork.com/2025/05/05/nih-shuts-down-final-beagle-lab-ending-decades-of-painful-dog-experiments/ I have mixed feelings about that. The gut microbiome is a major factor in why animal...
  11. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Dr Bhattacharya is already mentioning the gut microbiome as a potential cause of autism on Fox News. This is great news for us. https://www.youtube.com/watch?v=Ydp3XXTqUMM At 3:00 he also says "things that happen during pregnancy", which I think is correct. I think it's mostly due to poor...
  12. Michael Harrop

    Diet Diet outperforms microbial transplant to drive microbiome recovery in mice (April 2025)

    I'm going to reiterate that I think further argumentation is not useful until we can actually read the study. I disagree. Your intentions are irrelevant. The study's conclusions are the topic of discussion. Of course it does. You're missing the "host-native microbes that have been evolving...
  13. Michael Harrop

    Diet Diet outperforms microbial transplant to drive microbiome recovery in mice (April 2025)

    That's irrelevant. Their central claim is that simply feeding mice "regular chow" reconstitutes their microbiome after antibiotics. I don't agree. And it's not a "hint", it's an extremely bold claim. You're playing down their claims & conclusions, but other people will not. I think further...
  14. Michael Harrop

    Article New vaccine to treat 15 types of cancer now available on NHS. New jab, nivolumab, will treat skin, bladder and oesophagus cancer, with 1,200 patients a month receiving it (May 2025)

    https://www.independent.co.uk/news/health/cancer-vaccine-treatment-nhs-england-b2742432.html
  15. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    I didn't ambush Sanders. I waited outside his office along with a dozen other journalists. His staff knew we were there. This is very normal in those office buildings. I politely asked him a very reasonable question and then mentioned something that would help all the people he claims to care...
  16. Michael Harrop

    Sharing my daughter's experience with FMT for bipolar disorder

    It doesn't belong in Kate's thread, so here's a new thread: Discussion of Jane Dudley's website as a source of reputable information on the microbiome and FMT
  17. Michael Harrop

    Discussion of Jane Dudley's website as a source of reputable information on the microbiome and FMT

    If one reviews the link I shared, it should be quite obvious. Compare the Where to get FMT page with her "FMT Clinics" document. A specific example is her heavy reliance on hearsay, which is heavily contradicted by the public evidence. I see she cites my wiki and capsule-making video in one of...
  18. Michael Harrop

    Diet Diet outperforms microbial transplant to drive microbiome recovery in mice (April 2025)

    The large body of evidence indicates that antibiotics do permanent damage. They kill off the host-native microbes that have been evolving alongside us for millions of years and get passed down generationally. Presumably, they are feeding the mice regular chow in most experiments that don't...
  19. Michael Harrop

    Fungi Fungus from the human gut slows liver disease in mice (Apr 2025) Fusarium foetens, A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis

    https://www.nature.com/articles/d41586-025-01360-0 https://www.science.org/doi/10.1126/science.adp5540
  20. Michael Harrop

    Seeking to heal my broken gut, help and expertise requested!

    Did you review the wiki? https://humanmicrobiome.info/fmt/
  21. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine (Apr 2025, n=18)

    The Emory IRB? Eh, I'm not too sure about that. I expect they would take some time to review and discuss it internally, and I doubt they'd directly update me with their conclusions. But it's like asking the police to police themselves. Your link is one of the most common uses of Pubpeer...
  22. Michael Harrop

    Diet Diet outperforms microbial transplant to drive microbiome recovery in mice (April 2025)

    Some very bold claims locked behind a paywall. There is a large body of evidence contradicting their claims (https://humanmicrobiome.info/antibiotics/). Until this is made open-access, it should be ignored by the general public. One example is that mice naturally eat each other's poop, so we'd...
  23. Michael Harrop

    Sharing my daughter's experience with FMT for bipolar disorder

    I checked some of the links on that page, and I would say that should not be "go-to" information to give to people, especially not by itself without any disclaimer. It's missing some very important information & warnings, and is overall going to give people a very poor understanding of the...
  24. Michael Harrop

    Discussion of Jane Dudley's website as a source of reputable information on the microbiome and FMT

    I checked some of the links on that page, and I would say that should not be "go-to" information to give to people, especially not by itself without any disclaimer. It's missing some very important information & warnings, and is overall going to give people a very poor understanding of the...
  25. Michael Harrop

    My FMT Journey: From rock bottom gut health to possible healing (34M)

    There's not much to go on, but it sounds like it could be a bad donor. If I get bad side effects after eating something good is it die-off? A Herxheimer reaction? Keto flu? | Microbiome FAQ https://www.humanmicrobes.org/fmt-clinician-guidance
  26. Michael Harrop

    FMT Fecal microbiota transplantation cured epilepsy in a case with Crohn’s disease: The first report (2017)

    Your first question indicates a lack of understanding of the current situation, and implies that you haven't read this: https://forum.humanmicrobiome.info/threads/my-detailed-experiences-lessons-from-13-different-fmt-donors-jun-2018.53/ After you do, you will learn that this is largely an...
  27. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine (Apr 2025, n=18)

    Well, I got a nice surprise today. I received a response from the Emory IRB. Better than silence, but I don't see this as a solution either. I've merely passed the info on to one of hundreds of IRBs. I think this kind of unethical trial needs much more public attention. I think more effective...
  28. Michael Harrop

    FMT Fecal microbiota transplantation cured epilepsy in a case with Crohn’s disease: The first report (2017)

    Thank you for sharing! I'll add this to the wiki. I don't think this is an option at all. There are no good sources abroad. Someone even tried going to the Hadza for FMT and their results were not good. I think these are the only real options...
  29. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    I have spoken to dozens of Congresspeople at this point. I was planning on listing each individually, like before, but I don't think that would be useful right now. For the members of the Senate Health Committee, not a single staff member passed on the information or mentioned anything about it...
  30. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    RFK statement: https://www.youtube.com/watch?v=w9D-9lNV5JY I've listened to "experts" in the news ridicule and criticize his statement, but in this case, most of them were quite ignorant themselves, and RFK has the opportunity to demonstrate them to be such if the conclusion of this effort...
  31. Michael Harrop

    FMT Early-life FMT induced profound, long-lasting effects on adipose tissue function and systemic glucose homeostasis (2025) Effects of Children's Microbiota on Adipose and Intestinal Development in Sex-Matched Mice Persist into Adulthood Following a Single Fecal Microbiota Transplantation

    https://www.sciencedirect.com/science/article/pii/S221287782500064X
  32. Michael Harrop

    Sharing my daughter's experience with FMT for bipolar disorder

    Thank you for sharing! It would be helpful if you could question her for as much of this information as possible!
  33. Michael Harrop

    FMT The gut microbiota promotes pain in fibromyalgia (Apr 2025, n=14) FMT from FM patients to mice, and from healthy human donors to FM patients

    https://www.cell.com/neuron/fulltext/S0896-6273(25)00252-1
  34. Michael Harrop

    Enhancing Mucosal microbiota transplant, clearing the gut mucosa prior to FMT

    1. The difference between the microbiome of the mucosa vs feces. 2. Clearing the mucosa. From the OP: Yes, I'm sure biofilms are an important part of it. https://forum.humanmicrobiome.info/tags/biofilm/. It would be great if we could solve this by taking a biofilm disolver for a week prior to...
  35. Michael Harrop

    Article Lawsuit could challenge trust in Ozempic and other popular weight loss drugs (Jun 2024, Wegovy, Rybelsus, semaglutide) [Collection of info]

    Lawsuit alleges Maryland man with diabetes became blind after taking Ozempic. The lawsuit accuses drug manufacturer Novo Nordisk of failing to warn patients of the possible association between the popular drug and an eye condition called NAION. (Apr 2025)...
  36. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine (Apr 2025, n=18)

    I've moderated large groups for 10+ years. Pubpeer's moderation is horrendous. It's bad enough for me to want to urge people to boycott their website, despite it being a hugely important project. I strongly disagree with your characterization of the citation I shared. It's ridiculous to expect...
  37. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine (Apr 2025, n=18)

    Here's the full quote: I think that's exactly what I did; present the facts. I don't think I made allegations of misconduct. Yes I did. The link I included specifically backs up my claims with dozens of primary citations. I don't agree with that characterization. I linked directly to a list...
  38. Michael Harrop

    Virome Common Virus May Improve Skin Cancer Treatment Outcomes (Apr 2025, n=341) CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade

    https://www.cancer.ox.ac.uk/news/new-study-finds-common-virus-may-improve-skin-cancer-treatment-outcomes https://www.nature.com/articles/s41591-025-03647-1
  39. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine (Apr 2025, n=18)

    Wow, Pubpeer is apparently still absolute garbage. They remove comments completely arbitrarily. This is the comment they removed: If you ask them why, they simply point you to their commenting guidelines, which my comment very obviously does not violate.
  40. Michael Harrop

    Enhancing Mucosal microbiota transplant, clearing the gut mucosa prior to FMT

    Oh my, you're going down the path of SFBayFMT5 (adding useless, erroneous noise via uninformed opinions, poor reading comprehension, and not taking into account previous discussion/information). I'll save my breath for them then. But you're already wrong since FMT researchers already thought it...
Back
Top