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  1. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Thanks @indigo34 for accompanying me to the Senate offices for a day! Hopefully two people will be twice as effective :) NIH: I confirmed that Building 1 is where the Office of the Director is. https://orf.od.nih.gov/AboutORF/BFM/Pages/01Beth.aspx I contacted ORS...
  2. Michael Harrop

    FMT Exercised gut microbiota improves vascular and metabolic abnormalities in sedentary diabetic mice through gut‒vascular connection (Jan 2025)

    https://www.sciencedirect.com/science/article/pii/S2095254625000043
  3. Michael Harrop

    FVT Bacterial and viral assemblages in ulcerative colitis patients following fecal microbiota and fecal filtrate transfer (Dec 2024, n=6)

    https://academic.oup.com/ismecommun/article/5/1/ycae167/7931473 Some interesting findings. A comparison of FVT & FMT.
  4. Michael Harrop

    Antibiotics Shorter, smarter, safer: Short-course antibiotics can revolutionize healthcare (Nov 2024, n=460) Cost-effectiveness of a short-course antibiotic treatment strategy for the treatment of ventilator-associated pneumonia: an economic analysis of the REGARD-VAP trial

    https://www.sciencedaily.com/releases/2025/01/250121130033.htm https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00327-9/fulltext People on reddit love to spread the harmful "You must finish the whole course" misinformation. https://humanmicrobiome.info/antibiotics/
  5. Michael Harrop

    Antibiotics Antibacterials are everywhere: for the sake of our microbiome, we need to control their use (Jan 2025) Microbiotoxicity: A call to arms for cross-sector protection of the human microbiome

    https://theconversation.com/antibacterials-are-everywhere-for-the-sake-of-our-microbiome-we-need-to-control-their-use-247723 https://www.sciencedirect.com/science/article/pii/S0163445325000027
  6. Michael Harrop

    Sharing My Autoimmune Recovery Journey + Solutions for your Gut Health (GAIP diet)

    I've essentially already tried GAIP. I tolerate flax and chia seeds very poorly. It seems plausible that this diet can help clear problematic components for some people. I read his "How not to die" book and liked it. I'm generally a fan of his, but his info on FMT is quite poor and contains...
  7. Michael Harrop

    FMT Microbiota transplantation reduces recurrence of brain disorder in patients with advanced liver disease (Jan 2025, n=60) Microbiota transplant for hepatic encephalopathy in cirrhosis: The THEMATIC trial

    https://www.legacynewspaper.com/study-microbiota-transplantation-reduces-recurrence-of-brain-disorder-in-patients-with-advanced-liver-disease/ https://www.journal-of-hepatology.eu/article/S0168-8278(25)00005-4/fulltext Their donors are awful, but researchers keep using them because of the...
  8. Michael Harrop

    Sharing My Autoimmune Recovery Journey + Solutions for your Gut Health (GAIP diet)

    That's extremely lucky. But your personal experience does not translate to everyone else. I have eaten plant-based diets, 100% raw vegan, 100% raw paleo, etc. If they're not present you can't feed them. Missing Microbes with Dr Martin Blaser (American Society for Microbiology, 2016)...
  9. Michael Harrop

    Sharing My Autoimmune Recovery Journey + Solutions for your Gut Health (GAIP diet)

    This doesn't appear to make sense. Your cure was a temporary elimination diet? Then when you added back the foods without doing anything else, you could tolerate them fine? I also eat based on an elimination diet. It's not a solution, it's a method to prevent the worst symptoms. It doesn't fix...
  10. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    I actually contacted Daisy Robinton when she was associated with Harvard. This was a decade ago I think, when I was contacting individuals to ask them to be a stool donor for me. She responded and initially seemed willing but then chickened out. I contacted her more recently after she moved to...
  11. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    This should not be relevant. Patients should be able to advocate for treatment access without having credentials/institutional affiliations. Especially when a ton of scientific evidence is presented. Additionally, there are major deficiencies with "credendials" and "institutions" [1][2][3]. The...
  12. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    I did say that to Senator Cassidy's office. I believe it's true too, which is one of the many reasons it seems bizarre that these politicians aren't jumping at the chance to champion this. Marco Rubio is focused on trying to become Secretary of State, but it wouldn't hurt to follow up with his...
  13. Michael Harrop

    FMT Methodology, efficacy and safety of fecal microbiota transplantation in treating inflammatory bowel disease (2020, review). Possible herpes zoster (shingles) transfer, and herpes also reported as adverse event in a placebo group

    This one mentions herpes zoster (shingles): The Safety of Fecal Microbiota Transplantation for Crohn’s Disease: Findings from A Long-Term Study (2018) https://link.springer.com/article/10.1007/s12325-018-0800-3 They screened for herpes simplex virus: I don't see herpes mentioned in the...
  14. Michael Harrop

    FMT Methodology, efficacy and safety of fecal microbiota transplantation in treating inflammatory bowel disease (2020, review). Possible herpes zoster (shingles) transfer, and herpes also reported as adverse event in a placebo group

    It's not part of the standard screening criteria. https://humanmicrobiome.info/fmt/#screening I don't see how. I think you're right. Their table is very hard to read on small screens (mine currently). It does appear that all reports for herpes are under "placebo". I'll change the thread title.
  15. Michael Harrop

    FMT Methodology, efficacy and safety of fecal microbiota transplantation in treating inflammatory bowel disease (2020, review). Possible herpes zoster (shingles) transfer, and herpes also reported as adverse event in a placebo group

    https://www.sciencedirect.com/science/article/pii/S2590097820300252 You can search the page for "herpes". It's in Section 5, Short-term and long-term safety of FMT in IBD. It apparently occurred in multiple studies. It's listed under "placebo". NSAE = Non-serious adverse events.
  16. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    What SFBayFMT5 said is correct, but SFBayFMT5 misunderstood what bizzoc was asking, and thus the statement "this concept is correct" is false.
  17. Michael Harrop

    Procedure Re crapsules, what are the optimal conditions to consume them?

    Virtually every case. That's one of their main functions.
  18. Michael Harrop

    Study Study Links High Fluoride Exposure to Lower I.Q. in Children (Jan 2025) Fluoride Exposure and Children’s IQ Scores. A Systematic Review and Meta-Analysis

    https://www.nytimes.com/2025/01/08/health/fluoride-children-iq.html https://jamanetwork.com/journals/jamapediatrics/fullarticle/2828425
  19. Michael Harrop

    Procedure Re crapsules, what are the optimal conditions to consume them?

    Yes, but it's much more than that. There's also the mucus layer and the immune system. There are many components of the gut microbiome that hinder colonization. No such thing. The closest thing is "germ-free mice". Antibiotics have not worked for this purpose in humans...
  20. Michael Harrop

    FMT Fecal transplant shows promise for diabetic gastroenteropathy (Dec 2024, n=20) Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trial

    https://www.eurekalert.org/news-releases/1069871 https://medicalxpress.com/news/2025-01-fecal-transplant-diabetic-gastroenteropathy-treatment.html https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00579-0/fulltext
  21. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Bernie Sanders, MAHA I saw this "Make America Healthy Again" video by Bernie Sanders shortly before going to the Senate building. It frustrated me that he's constantly talking about taking on the pharmaceutical industry, lowering prescription drug prices, etc., while ignoring the fact that a...
  22. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    This will absolutely not reverse or remove harms from FMT. "Herbal" may also not be any less harmful: https://humanmicrobiome.info/antibiotics/#general You need to review the Testing page of the wiki. What you're doing is erroneous. That's not correct. This is why diet is extremely limited...
  23. Michael Harrop

    Other Fecal samples and rectal swabs adequately reflect the human colonic luminal microbiota (Oct 2024, n=10)

    I agree. I have not checked the other studies for that piece of info.
  24. Michael Harrop

    Procedure Is there any chance double layered crapsules don't open at all and pass through whole?

    It depends on what exact capsules are used. With Human Microbes, we use vegan delayed-release capsules. Gelatin capsules are also common and occasionally used. You can do tests yourself by placing them in various liquids. They expand, soften, and break down within 1 hour usually. No acids or...
  25. Michael Harrop

    Human Microbes HumanMicrobes.org, Donor NY-KS-1998. Treating CFS, IBS, mild Alzheimers. Large improvements to skin, stool quality, IBS. Mild to moderate improvements to fatigue, sleep, sex drive. Time to focus on Step #3 (2024)

    I don't recall seeing any study using helminths to destroy the mucosa. I doubt they would "destroy it", but perhaps they could contribute to replacing it. I haven't tried them myself since they seem to be far less studied & promising than FMT. I'm certainly open to the possibility. I don't doubt...
  26. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    Not necessarily. Breastfeeding is not the only, nor a complete, method of transfer from mother to child, and the mother would need to have the strains herself. Plausibly. But it's highly speculative. Those are genera and species, not strains.
  27. Michael Harrop

    Recovery plan for 9yo following antibiotics for Lyme

    That may result in mild improvements, but FMT is the only thing that comes close to being a complete microbiome restoration method. The FAQ page of the wiki covers this: https://humanmicrobiome.info/faq/
  28. Michael Harrop

    Blog Is a million dollars enough for your poop? Highly effective stool donors will now be paid 1 million dollars for their poop. And offering a half-a-million-dollar reward for anyone who recruits one. (Jul 2024, HumanMicrobes.org)

    Ah. I was thinking it might be useful to contact him (https://www.linkedin.com/in/jordanmichaelfuller/) but then I saw their health project is just selling supplements (https://fullerhealth.com/). She's been getting updates.
  29. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    I wouldn't be so sure. Studies have shown both benefits and detriments from aFMT. If it's correct that the dark type 3 stools he wants to ingest are "good" and have a higher percentage of "desirable" microbes, aFMT with those stools could help increase the number of those microbes along the...
  30. Michael Harrop

    Donors Smelly donor stool

    My stool generally changes to be more like the donor's. Interesting! Looking forward to your full reports. There are way too many other possible factors to conclude that. Even for some of the observations you've made, they could be due to variations from one stool to another, from the same...
  31. Michael Harrop

    Donors FMT - good Idea for my circumstance? Plus list of donor possibilities

    Yes, I think I started out with a good ability to select donors (as I discussed in the Intro). The main problem has always been donor availability. I haven't been able to find a donor that matches the two most effective ones I tried early on. But Donor 8 was similar, as was Donor 11 (FL-RS). And...
  32. Michael Harrop

    Procedure Re crapsules, what are the optimal conditions to consume them?

    This is covered here: https://www.humanmicrobes.org/ordering-faq https://humanmicrobiome.info/fmt/ Much of it is experimental. In my experience, a huge dose like that is much less effective than small doses spread out for a long period. I think it has to do with colonization resistance.
  33. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    That's not a health symptom, so I'd ignore it. You can experiment to see if you notice any health symptoms associated with those stool changes. If you don't notice any then it's most likely not worth worrying about. It's probably more accurate to see it as missing microbes (a deficiency)...
  34. Michael Harrop

    Blog Is a million dollars enough for your poop? Highly effective stool donors will now be paid 1 million dollars for their poop. And offering a half-a-million-dollar reward for anyone who recruits one. (Jul 2024, HumanMicrobes.org)

    Yes, one of the many people who should be supporting a project like this. I think she briefly contacted me to inquire about ordering. She should be aware of everything going on, and she's even married to a seemingly very healthy NFL player, so she already has inroads for recruiting there, yet...
  35. Michael Harrop

    Autologous Autologous type-3 FMT (dark brown), Floraphage

    All of this is highly experimental. If you have no symptoms, the risks may not be worth any possible benefit.
  36. Michael Harrop

    Has anyone tried making the yogurt with l. Reuteri using Dr. William Davis' method and found relief and healing?

    That's a 2-hour video; you should give a better reference. Here is some info: https://humanmicrobiome.info/probiotic-guide/#some-additional-citationsinfo Can I cultivate store bought probiotic in Kefir? Attempting to extend/boost probiotics with home ferments
  37. Michael Harrop

    Blog Is a million dollars enough for your poop? Highly effective stool donors will now be paid 1 million dollars for their poop. And offering a half-a-million-dollar reward for anyone who recruits one. (Jul 2024, HumanMicrobes.org)

    I don't think that conflicts with my position. And it doesn't appear that they tested "micro-FMT or probiotic-sized doses"? Ah. I could be wrong but I don't think that precise level of age-matching is required. This for sure. https://humanmicrobiome.info/testing/
  38. Michael Harrop

    Blog Is a million dollars enough for your poop? Highly effective stool donors will now be paid 1 million dollars for their poop. And offering a half-a-million-dollar reward for anyone who recruits one. (Jul 2024, HumanMicrobes.org)

    I've had mothers apply for their 1-2 year old babies, and many of them have solid stools. I think these 1-2-year-olds could be stool donors for anyone, including newborns. In fact, before they fell through, my #1 donor (humanmicrobes.org early on) was a 1-2-year-old with a good stool type. For...
  39. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Wow! Yes I am! Currently, I've completed everything I can think of, and I'm pondering what to do next. Someone shared email addresses to contact RFK's team, so I emailed them. I also contacted all the members of the MAHA caucus. I think the RFK angle is complete until he gets approved to the...
  40. Michael Harrop

    Donors Smelly donor stool

    Let us know how it goes! /forums/fmt-personal-donor-experiences/
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