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  1. Michael Harrop

    Post Lyme Dysbiosis

    The evidence in the wiki strongly suggests that these conditions all stem from gut dysbiosis, and thus FMT is the solution. You'll have to read this and get involved: https://forum.humanmicrobiome.info/threads/the-fda-and-fmt-regulation-part-2-jul-2024-humanmicrobes-org-i-met-wit.520/post-1370...
  2. Michael Harrop

    Sources Questions about humanmicrobes.org donors

    That information is in the results-tracking spreadsheet on the Orders page.
  3. Michael Harrop

    Other Scientists identify bacterial glycogen as a gut trigger behind ALS and dementia (Jan 2026) C9orf72 in myeloid cells prevents an inflammatory response to microbial glycogen

    https://www.sciencedaily.com/releases/2026/04/260408225944.htm https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01678-X
  4. Michael Harrop

    FVT Fecal virome transplantation attenuates arthritis in mice by remodeling gut ecology, systemic tryptophan metabolism, and innate immune responses (Apr 2026)

    https://www.nature.com/articles/s41522-026-00980-2
  5. Michael Harrop

    Other Bacteria are weaving forever chemicals directly into their cell membranes (Mar 2026) Bacteria covalently incorporate polyfluoroalkyl carboxylates into membrane lipids

    https://phys.org/news/2026-04-bacteria-chemicals-cell-membranes.html https://www.nature.com/articles/s41564-026-02301-x
  6. Michael Harrop

    Sources Dr Paul Froomes in Melbourne, AU is treating bipolar, autism, and more with FMT

    He's covered in the wiki: https://humanmicrobiome.info/where-to-get-fmt/#dr-paul-froomes-au I don't think there's anything "great" about that. One simplistic, verbal report from the doctor treating the patient (hearsay from a biased source) is next to meaningless. In fact, it's a red flag that...
  7. Michael Harrop

    Article EPA, HHS Announce Historic Actions to Protect Americans from Microplastics and Safeguard Drinking Water. ARPA-H launches groundbreaking, $144 million program to combat microplastics in the human body (Apr 2026)

    https://www.epa.gov/newsreleases/epa-hhs-announce-historic-actions-protect-americans-microplastics-and-safeguard https://www.hhs.gov/press-room/arpa-h-launches-groundbreaking-144-million-program-combat-toxic-microplastics-human-body.html...
  8. Michael Harrop

    Diet Stools suggest why Papua New Guineans on low-protein diet are muscular. Excreta-related research at the University of Tokyo (Apr 2026)

    https://www.u-tokyo.ac.jp/focus/en/features/z1304_00300.html
  9. Michael Harrop

    We used FMT for recurrent cholangitis in bile duct cancer – strong response but new abdominal pain and gas

    Gas comes from changes/instability. If you eat something your gut can't handle, or which causes a significant shift in your microbiome, that causes gas. It can get painful when it's significant enough. I don't think that's a useful/valid notion. See: FMT donor matching and selection, screening...
  10. Michael Harrop

    Vagina Vaginal microbiota transplantation for treatment of vaginal dysbiosis without the use of antibiotics: a double-blind, randomised controlled trial in women with vaginal dysbiosis (Mar 2026, n=49) "VMT without antibiotics did not significantly improve microbiome conversion in this trial"

    https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00222-8/fulltext
  11. Michael Harrop

    Study Breakdown products from 'eco-friendly' plastics impede fetal development in mice (Mar 2026) Oligomeric lactic acid nanoplastics induce intrauterine growth restriction in mice by disrupting GATA2-mediated placental vascular development

    https://medicalxpress.com/news/2026-03-breakdown-products-eco-friendly-plastics.html https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003676
  12. Michael Harrop

    Donors Donor quality and stool type hypothesis for FMT (Fecal Microbiota Transplant)

    Another component of this hypothesis is that it seems like the colon does not want to be covered in poop; it wants to be covered in mucus. Being smeared with poop interferes with the mucus barrier & functions it performs. So if you can pick up a piece of poop and only get mucus on your hand...
  13. Michael Harrop

    FMT Faecal microbiota transplant for chronic norovirus infection: a case report of donor microbiota engraftment without clinical success (Mar 2026)

    https://academic.oup.com/gastro/article/doi/10.1093/gastro/goag015/8512970
  14. Michael Harrop

    FMT Her son needed a fecal transplant for a fearsome C. diff infection. Getting one required a tortuous journey. Stricter FDA stool bank rules made the treatment harder to find (Mar 2026)

    https://www.statnews.com/2026/03/23/c-diff-fda-drug-approval-access-paradox-fecal-transplants/
  15. Michael Harrop

    Other Popularity and acceptance of FMT. Who is to blame for why FMT will never be available? Ignorance, laziness, and apathy of the general public? How to motivate people to take action?

    I'm making $0 off FMT. I illegally made minimum wage off FMT for 2 years. More nonsense. There are real solutions; you're proposing fantastical notions instead.
  16. Michael Harrop

    Other Popularity and acceptance of FMT. Who is to blame for why FMT will never be available? Ignorance, laziness, and apathy of the general public? How to motivate people to take action?

    There are plenty of healthy people in the US. Both ideal donors I found were in the US. That is due to your own ignorance and poor judgment. Stool & blood tests are not a valid method of determining donor safety or efficacy, and that's been discussed & documented extensively on this forum and...
  17. Michael Harrop

    FMT Faecal Microbiota Transplantation Improves Outcomes in Depression (Mar 2026, n=46) A study on the efficacy and safety of fecal microbiota transplantation as an adjunctive therapy for treating depressive episodes

    https://www.emjreviews.com/neurology/news/faecal-microbiota-transplantation-improves-outcomes-in-depression/ https://www.nature.com/articles/s41598-026-41801-y
  18. Michael Harrop

    Other What is the public perception of FMT? How much does it matter? Has it been blocking progress?

    I don't agree because I don't observe this. There are some degree holders who spread misinformation (about many things, not only FMT and the microbiome), but they are relatively small fish in the grand scheme of things. That's a problem specific to reddit and /r/microbiome in particular...
  19. Michael Harrop

    Other Popularity and acceptance of FMT. Who is to blame for why FMT will never be available? Ignorance, laziness, and apathy of the general public? How to motivate people to take action?

    That was not a hostile or harsh tone. There are plenty of people who are severely impacted in those areas of life by their health. They still do nothing. I noted in other threads that I've contacted such groups (IE: CFS - chronic fatigue syndrome) and even went to an event in DC and spoke to...
  20. Michael Harrop

    Other Popularity and acceptance of FMT. Who is to blame for why FMT will never be available? Ignorance, laziness, and apathy of the general public? How to motivate people to take action?

    This is completely erroneous. Chronic disease and poor health already afflict the vast majority of the population. They can't try FMT because safe and effective donors are not available, and will never be because people are too ignorant and lazy to do anything to make them so. They're not...
  21. Michael Harrop

    FMT Gut microbiota modulation via repeated donor fecal transplantation improves motor and gastrointestinal symptoms in drug-naïve Parkinson’s disease: a randomized phase 2 trial (Mar 2026, n=72)

    https://www.nature.com/articles/s41392-026-02604-9
  22. Michael Harrop

    10-year-old Emma puts severe Ulcerative Colitis in remission with DIY FMT from her mom (2013)

    https://www.youtube.com/watch?v=E-5-QOjTkEs A second video with a little more info: https://www.youtube.com/watch?v=xLIndT7fuGo It references this blog, but most of the saves are unavailable https://web.archive.org/web/20130113144423/http://thepowerofpoo.blogspot.com/ Donor: Mother. The...
  23. Michael Harrop

    Aging Scientists Tried to Age Young Ovaries with Old Microbes but Accidentally Made Them More Fertile (Mar 2026) Estropausal gut microbiota transplant improves measures of ovarian function in adult mice

    https://www.zmescience.com/ecology/animals-ecology/young-ovaries-old-microbes/ https://www.nature.com/articles/s43587-026-01069-3
  24. Michael Harrop

    Rod Clair does successful FMT from his wife for diverticular disease, IBS, severe gastritis, chronic fatigue, and more (Dec 2021, fecal microbiota transplant)

    https://www.youtube.com/watch?v=pN1VV_zauDU Her stool quality looks pretty good. He takes one small dose every 1-7 days. It seems that he still has some brain fog and weight gain.
  25. Michael Harrop

    Causation Memory loss is fuelled by gut microbes in ageing mice (Mar 2026) Intestinal interoceptive dysfunction drives age-associated cognitive decline

    https://www.nature.com/articles/d41586-026-00768-6 https://www.nature.com/articles/s41586-026-10191-6
  26. Michael Harrop

    Antibiotics A single course of antibiotics can leave a lasting mark on the gut microbiome (Mar 2026) Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals

    https://www.scientificamerican.com/article/a-single-course-of-antibiotics-may-reshape-the-gut-microbiome-for-years/ https://www.nature.com/articles/s41591-026-04284-y
  27. Michael Harrop

    Causation Specific gut bacteria species linked to muscle strength (Mar 2026) Roseburia inulinivorans increases muscle strength

    https://medicalxpress.com/news/2026-03-specific-gut-bacteria-species-linked.html https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336980
  28. Michael Harrop

    FMT Why some gut microbes persist after fecal transplants (Feb 2026) Temporal dynamics of gut biosynthetic gene clusters link persistent colonization and engraftment in fecal microbiota transplantation

    https://medicalxpress.com/news/2026-03-stay-stray-gut-microbes-persist.html https://www.tandfonline.com/doi/full/10.1080/19490976.2026.2634469
  29. Michael Harrop

    Phages A virus hiding inside bacteria may help explain colorectal cancer (Feb 2026, n=877) Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis

    https://theconversation.com/a-virus-hiding-inside-bacteria-may-help-explain-colorectal-cancer-276695 https://www.nature.com/articles/s43856-026-01403-1
  30. Michael Harrop

    Article Top FDA Official Resigns Under Pressure (Jul 2025) After turning down several new drugs and restricting use of another, Dr. Vinay Prasad drew the ire of the right-wing influencer Laura Loomer and others

    He resigns again: https://www.nytimes.com/2026/03/06/health/fda-prasad-resigns.html
  31. Michael Harrop

    Other Sleep disruption damages gut's self-repair ability via stress signals from brain (Feb 2026) Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

    https://news.uci.edu/2026/02/05/sleep-disruption-damages-guts-self-repair-ability-via-stress-signals-from-brain/ https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(26)00025-1
  32. Michael Harrop

    Other Hidden biological signals in the gut point to Alzheimer’s as a whole-body disorder (Jan 2026) Gut proteome and microbiome alterations: Analysis of transverse colon samples from pathologically confirmed Alzheimer's disease patients

    https://news.asu.edu/20260116-science-and-technology-roots-alzheimers-disease-extend-beyond-brain https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.71021Abstract
  33. Michael Harrop

    Sources Getting lab test results for donors at FMT clinics

    List the clinics you contacted. You definitely shouldn't use any of them. Test results are a bare minimum, and are not adequate to determine safety & efficacy. So if they're not even willing to share that information, then they're definitely not willing to share the important things.
  34. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Casey Means Senate HELP hearing: https://www.help.senate.gov/hearings/nomination-of-casey-means-to-be-medical-director-in-the-regular-corps-of-the-public-health-service-and-surgeon-general-of-the-public-health-service At 50 minutes in, it's noted that she's making hundreds of thousands of...
  35. Michael Harrop

    Testing Gut health index measures microbial interactions to track disease (Feb 2026) Imbalance in gut microbial interactions as a marker of health and disease

    https://medicalxpress.com/news/2026-02-gut-health-index-microbial-interactions.html https://www.eurekalert.org/news-releases/1117082 https://www.npr.org/2026/02/27/nx-s1-5724876/scientists-find-a-new-clue-to-help-them-identify-a-healthy-gut-microbiome...
  36. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome remodeling reduces neuroinflammation in traumatic brain injury (Feb 2026, mice)

    https://neurosciencenews.com/microbiome-tbi-brain-neuroinflammation-30201/ https://www.eurekalert.org/news-releases/1117939 https://www.nature.com/articles/s42003-026-09737-1
  37. Michael Harrop

    Testing Same Poop, Different Results: At-Home Gut Health Tests Are Wildly Inconsistent (Feb 2026) Evaluating the analytical performance of direct-to-consumer gut microbiome testing services

    https://gizmodo.com/same-poop-different-results-at-home-gut-health-tests-are-wildly-inconsistent-study-finds-2000726793 https://www.scientificamerican.com/article/at-home-microbiome-tests-reveal-dramatically-different-results/...
  38. Michael Harrop

    Genetics New Study Links Gut Makeup to Celiac Disease Pathogenesis (Feb 2026, n=12,652) The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition

    https://www.medcentral.com/gastroenterology/new-study-links-gut-makeup-to-celiac-disease-pathogenesis https://www.nature.com/articles/s41588-026-02502-4
  39. Michael Harrop

    Sources Comparing commercial FMT providers

    It's hearsay. You should encourage those people to post their full, detailed experience here.
  40. Michael Harrop

    Discussion How should we handle preprints?

    I think it's a bad idea to post preprints for the following reasons: There is more coverage and discussion when they're published. So it's better to just wait till then. They sometimes change the title when it's published, and searching titles is generally how we find previous...
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