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  1. Michael Harrop

    How I got off imodium/loperamide. Identify the root cause and the appropriate tool to solve it (FMT, Cholestyramine).

    The OP was correct. The collapse was probably not due to stopping the one imodium, but rather, olive oil, and perhaps other similar dietary ingredients. This is also because the FMT donor I was using is weak for restoring bile acid metabolism. Imodium is a broad-spectrum tool, but not really...
  2. Michael Harrop

    The power of olive oil -- significant changes to gut microbiome, stool, and food tolerances

    I think the olive oil intolerance is due to the acids, because the intolerance gets worse when I'm lacking the microbes needed for bile acid metabolism (BAM), and the symptoms are very similar to eating fat without Cholestyramine when my BAM is poor.
  3. Michael Harrop

    Sources Sourcing FMT. Where to get it?

    There is some related info in this thread: Comparing commercial FMT providers And in the wiki: Where to get FMT
  4. Michael Harrop

    Sources Comparing commercial FMT providers

    You shouldn't be engaging in FMT while still ignorant on such important things. It's covered: In the wiki: https://humanmicrobiome.info/fmt/ https://humanmicrobiome.info/where-to-get-fmt/ In this thread: Continued letters and complaints to the FDA, NIH, and HHS (Jan 2025, FMT) | Human...
  5. Michael Harrop

    Sources Gezonde Darmflora stool donors have diseases as proven by their blood tests?? Wtf??

    This is meaningless nonsense. Please don't post that kind of garbage on this forum. It's also off-topic for this thread.
  6. Michael Harrop

    FMT Replacing microbiota makes aging intestines young again (Jan 2026) Microbiota from young mice restore the function of aged ISCs

    https://www.eurekalert.org/news-releases/1113710 https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(25)00392-3
  7. Michael Harrop

    Oral Microbes living in our mouths could hold the key to obesity prevention (Jan 2026, n=628) Integrative multi-omics analysis reveals oral microbiome-metabolome signatures of obesity

    https://medicalxpress.com/news/2026-01-microbes-mouths-key-obesity.html https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01591-8 This appears to be correlation only. So it doesn't conflict with prior evidence indicating the gut microbiome is the crux that influences the oral microbiome...
  8. Michael Harrop

    Other Exhaled Breath Carries Disease-associated Bacteria from Gut (Jan 2026, n=41) The gut microbiota shapes the human and murine breath volatilome

    https://respiratory-therapy.com/disorders-diseases/infectious-diseases/other-infections/exhaled-breath-carries-disease-associated-bacteria-from-gut/ https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00544-3
  9. Michael Harrop

    Procedure DIY FMT Beginner's Questions

    Because they're regurgitating things they've read that sound plausible.
  10. Michael Harrop

    Procedure DIY FMT Beginner's Questions

    I typically use 10 lbs of dry ice in case there's a delay.
  11. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Bryan Johnson, I presume. It's been discussed in other threads. It appears his interest is in selling his own stool.
  12. Michael Harrop

    Sources I am considering going to IPPM clinic to do an FMT. Would you do it?

    There are no good sources of FMT because people are too lazy to take necessary action to remedy the situation.
  13. Michael Harrop

    Video The false promises of Bryan Johnson and Functional Medicine | The Bryan Johnson "Hit Piece". Surprising revelations in the New York Times put Johnson's integrity into question | Scott Carney

    Someone shared this article with me: https://zoe.com/learn/the-man-who-wants-to-live-forever-bryan-johnson. It shows that Bryan Johnson's main interest in FMT is in selling his own poop, or a supplement made from it.
  14. Michael Harrop

    Outcomes For anyone who has done FMT, did you have worsening symptoms in the few days after?

    In my experience, some donors can trigger an initial day-or-so of worsening symptoms before seeing subsequent improvements. With bad donors, they can worsen symptoms and cause new ones, and the symptoms don't go away. It can be difficult to immediately determine which is which. Adequate...
  15. Michael Harrop

    Sources Gezonde Darmflora stool donors have diseases as proven by their blood tests?? Wtf??

    Gezonde Darmflora is already covered in the wiki as a known poor source, so I'm not sure why you seem to have been counting on them. https://humanmicrobiome.info/where-to-get-fmt/ I haven't looked at their tests, but those kinds of blood tests can show current or prior infection. So be sure you...
  16. Michael Harrop

    FMT Washed microbiota transplantation relieves atopic dermatitis via gut–skin microbiome rebalancing (Jan 2026, n=23)

    https://www.hmpgloballearningnetwork.com/site/thederm/news/washed-microbiota-transplantation-improves-disease-severity-and-microbial https://link.springer.com/article/10.1186/s12866-026-04717-1
  17. Michael Harrop

    Other Why FMT specifically? Why focus on the colon microbiota, wouldn't it be better to transplant microbes from every part of the body that they are found in?

    Poop contains microbes from the entire digestive tract, including oral microbes. There are different percentages of microbes at different body sites due to the different environments. [1] When you transplant stool into another body site, the percentages of microbes will change due to the...
  18. Michael Harrop

    General health Using AI chatbots for medical advice

    AI chatbots may seem useful, but they are not reliable at all. They are prediction engines that predict the words most likely to come next, based on the data they've been fed (which is often very flawed). They often "hallucinate" or make things up.
  19. Michael Harrop

    FMT A man with auto-brewery syndrome gets relief from faecal transplant (Jan 2026, n=22) Gut microbial ethanol metabolism contributes to auto-brewery syndrome in an observational cohort

    https://www.newscientist.com/article/2510789-man-whose-gut-made-its-own-alcohol-gets-relief-from-faecal-transplant/ https://www.nature.com/articles/s41564-025-02225-y
  20. Michael Harrop

    Other The secret to human intelligence? It might be in our gut. Your gut microbes may have helped build the human brain—and could still be shaping how it works today (Jan 2026) Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment

    https://www.sciencedaily.com/releases/2026/01/260105165806.htm https://scitechdaily.com/your-gut-microbes-may-be-quietly-transforming-how-your-brain-works/ https://www.pnas.org/doi/10.1073/pnas.2426232122
  21. Michael Harrop

    Other Vaginal and gut microbiome dysbiosis linked to endometriosis (Dec 2025, n=22) Comprehensive Analysis of Vaginal and Gut Microbiome Alterations in Endometriosis Patients

    https://www.contemporaryobgyn.net/view/vaginal-and-gut-microbiome-dysbiosis-linked-to-endometriosis https://www.dovepress.com/comprehensive-analysis-of-vaginal-and-gut-microbiome-alterations-in-en-peer-reviewed-fulltext-article-IJWH I've contacted lots of women with endometriosis about this...
  22. Michael Harrop

    Causation A molecule produced by gut bacteria can trigger atherosclerosis (Jul 2025, n=400) Imidazole propionate is a driver and therapeutic target in atherosclerosis

    https://www.gutmicrobiotaforhealth.com/scientists-discover-that-a-gut-microbiota-molecule-causes-atherosclerosis/ https://www.nature.com/articles/s41586-025-09263-w
  23. Michael Harrop

    How does regular valtrex use impact microbiome?

    For that kind of thing, you can search pubmed or google scholar for "[drug name] microbiome". Valtrex is an antiviral, so not something I'd be especially concerned about when it comes to the microbiome.
  24. Michael Harrop

    What's wrong with my gut?

    Virtually everything you're inquiring about is covered in the wiki. FMT is the primary solution. You can use a site like https://examine.com/ to look up evidence for supplements & conditions. This is unlikely to be a solution due to donor quality problems...
  25. Michael Harrop

    Other Pesticides and other common chemical pollutants are toxic to our ‘good’ gut bacteria (Nov 2025) Industrial and agricultural chemicals exhibit antimicrobial activity against human gut bacteria in vitro

    https://www.cam.ac.uk/research/news/pesticides-and-other-common-chemical-pollutants-are-toxic-to-our-good-gut-bacteria https://www.nature.com/articles/s41564-025-02182-6
  26. Michael Harrop

    What's wrong with my gut?

    Did you review the FAQ? https://humanmicrobiome.info/faq/
  27. Michael Harrop

    Article Highly cited paper, backed by Monsanto and used as evidence that the herbicide Roundup is safe, is retracted by journal for serious ethical concerns (Dec 2025) Safety Evaluation and Risk Assessment of the Herbicide Roundup and Its Active Ingredient, Glyphosate, for Humans

    https://www.science.org/content/article/journal-retracts-weed-killer-study-backed-monsanto-citing-serious-ethical-concerns https://www.nytimes.com/2026/01/02/climate/glyphosate-roundup-retracted-study.html https://www.sciencedirect.com/science/article/pii/S0273230099913715
  28. Michael Harrop

    Modulate the microbiome with raw human/cow milk as alternative to FMT?

    Unfortunately, most people don't seem to see the value in documenting their experiments in a systematic manner that can be found & searched by other people. They just leave random comments here and there.
  29. Michael Harrop

    Donors Amish as stool donors for FMT

    In my experience, nearly everyone is horrible at judging stool quality, even after training them to identify the best stools, and it being in their interest to do so. I've only come across one other person besides me who seems to be capable of it. So it's either take the photos to show me...
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