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  1. Michael Harrop

    Other Why FMT specifically? Why focus on the colon microbiota, wouldn't it be better to transplant microbes from every part of the body that they are found in?

    That seems to largely be the case, but I don't think the research is conclusive.
  2. Michael Harrop

    Other Why FMT specifically? Why focus on the colon microbiota, wouldn't it be better to transplant microbes from every part of the body that they are found in?

    Poop contains microbes from the entire digestive tract, including oral microbes. There are different percentages of microbes at different body sites due to the different environments. [1] When you transplant stool into another body site, the percentages of microbes will change due to the...
  3. Michael Harrop

    What's wrong with my gut?

    AI chatbots may seem useful, but they are not reliable at all. They are prediction engines that predict the words most likely to come next, based on the data they've been fed (which is often very flawed). They often "hallucinate" or make things up.
  4. Michael Harrop

    FMT A man with auto-brewery syndrome gets relief from faecal transplant (Jan 2026, n=22) Gut microbial ethanol metabolism contributes to auto-brewery syndrome in an observational cohort

    https://www.newscientist.com/article/2510789-man-whose-gut-made-its-own-alcohol-gets-relief-from-faecal-transplant/ https://www.nature.com/articles/s41564-025-02225-y
  5. Michael Harrop

    Other The secret to human intelligence? It might be in our gut. Your gut microbes may have helped build the human brain—and could still be shaping how it works today (Jan 2026) Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment

    https://www.sciencedaily.com/releases/2026/01/260105165806.htm https://scitechdaily.com/your-gut-microbes-may-be-quietly-transforming-how-your-brain-works/ https://www.pnas.org/doi/10.1073/pnas.2426232122
  6. Michael Harrop

    Other Vaginal and gut microbiome dysbiosis linked to endometriosis (Dec 2025, n=22) Comprehensive Analysis of Vaginal and Gut Microbiome Alterations in Endometriosis Patients

    https://www.contemporaryobgyn.net/view/vaginal-and-gut-microbiome-dysbiosis-linked-to-endometriosis https://www.dovepress.com/comprehensive-analysis-of-vaginal-and-gut-microbiome-alterations-in-en-peer-reviewed-fulltext-article-IJWH I've contacted lots of women with endometriosis about this...
  7. Michael Harrop

    Causation A molecule produced by gut bacteria can trigger atherosclerosis (Jul 2025, n=400) Imidazole propionate is a driver and therapeutic target in atherosclerosis

    https://www.gutmicrobiotaforhealth.com/scientists-discover-that-a-gut-microbiota-molecule-causes-atherosclerosis/ https://www.nature.com/articles/s41586-025-09263-w
  8. Michael Harrop

    How does regular valtrex use impact microbiome?

    For that kind of thing, you can search pubmed or google scholar for "[drug name] microbiome". Valtrex is an antiviral, so not something I'd be especially concerned about when it comes to the microbiome.
  9. Michael Harrop

    What's wrong with my gut?

    Virtually everything you're inquiring about is covered in the wiki. FMT is the primary solution. You can use a site like https://examine.com/ to look up evidence for supplements & conditions. This is unlikely to be a solution due to donor quality problems...
  10. Michael Harrop

    Other Pesticides and other common chemical pollutants are toxic to our ‘good’ gut bacteria (Nov 2025) Industrial and agricultural chemicals exhibit antimicrobial activity against human gut bacteria in vitro

    https://www.cam.ac.uk/research/news/pesticides-and-other-common-chemical-pollutants-are-toxic-to-our-good-gut-bacteria https://www.nature.com/articles/s41564-025-02182-6
  11. Michael Harrop

    What's wrong with my gut?

    Did you review the FAQ? https://humanmicrobiome.info/faq/
  12. Michael Harrop

    Article Highly cited paper, backed by Monsanto and used as evidence that the herbicide Roundup is safe, is retracted by journal for serious ethical concerns (Dec 2025) Safety Evaluation and Risk Assessment of the Herbicide Roundup and Its Active Ingredient, Glyphosate, for Humans

    https://www.science.org/content/article/journal-retracts-weed-killer-study-backed-monsanto-citing-serious-ethical-concerns https://www.nytimes.com/2026/01/02/climate/glyphosate-roundup-retracted-study.html https://www.sciencedirect.com/science/article/pii/S0273230099913715
  13. Michael Harrop

    Modulate the microbiome with raw human/cow milk as alternative to FMT?

    Unfortunately, most people don't seem to see the value in documenting their experiments in a systematic manner that can be found & searched by other people. They just leave random comments here and there.
  14. Michael Harrop

    Donors Amish as stool donors for FMT

    In my experience, nearly everyone is horrible at judging stool quality, even after training them to identify the best stools, and it being in their interest to do so. I've only come across one other person besides me who seems to be capable of it. So it's either take the photos to show me...
  15. Michael Harrop

    Donors Amish as stool donors for FMT

    The main issues for me would be that they live in secluded areas, so they're not easy to screen & use. And because of their health issues, and from what video coverage I've seen of them, they don't seem promising enough as donors for me to want to bother with them. However, if someone else...
  16. Michael Harrop

    Donors Using an obese healthy child as a stool donor for FMT?

    There is no such thing as an obese, healthy person. https://humanmicrobiome.info/obesity/
  17. Michael Harrop

    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Someone posted on the Effective Altruism forums about it, and directly contacted a group of athletes involved with EA. Nothing came of it. I've commented on the EA and LessWrong websites about it, and have had some really poor responses that made me averse to those websites. Eliezer Yudkowsky...
  18. Michael Harrop

    Donors Where to get a stool donor for FMT or how to find one?

    There's a summary here: https://forum.humanmicrobiome.info/threads/the-fda-and-fmt-regulation-part-2-jul-2024-humanmicrobes-org-i-met-wit.520/#post-1370 In the US, an IND is required. Physicians can do single-patient INDs. It is a worldwide project, but I've paused all sales because I was...
  19. Michael Harrop

    Video The false promises of Bryan Johnson and Functional Medicine | The Bryan Johnson "Hit Piece". Surprising revelations in the New York Times put Johnson's integrity into question | Scott Carney

    Yes, I agree. I think I emailed a doctor he was working with, but I didn't find a contact for him specifically. I also replied to a related tweet he posted. Feel free to write to him. For a "call to action" I generally share this summary of the situation...
  20. Michael Harrop

    Study Fathers' microplastics exposure tied to their children's metabolic problems (Dec 2025) Paternal microplastic exposure alters sperm small non-coding RNAs and affects offspring metabolic health in mice

    https://medicalxpress.com/news/2025-12-fathers-microplastics-exposure-children-metabolic.html https://academic.oup.com/jes/advance-article/doi/10.1210/jendso/bvaf214/8383852
  21. Michael Harrop

    Diet A common food ingredient may shape a child’s health for life (Jul 2025, mice) Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibility. Carboxymethylcellulose and polysorbate-80

    https://www.sciencedaily.com/releases/2025/12/251225080732.htm https://www.nature.com/articles/s41467-025-62397-3
  22. Michael Harrop

    Diet Diet outperforms microbial transplant to drive microbiome recovery in mice (April 2025)

    Not for me.
  23. Michael Harrop

    Oral Super donor assessment tool for oral microbiome transplantation (Dec 2025, n=93)

    https://link.springer.com/article/10.1186/s12866-025-04630-z Paywalled.
  24. Michael Harrop

    Video Is SIBO real? SIBO vs dysbiosis? Debunking the SIBO hypothesis | Small Intestinal Bacterial Overgrowth

    Definitely.
  25. Michael Harrop

    FMT Awareness and perception of fecal microbiota transplantation in Lebanon: a cross-sectional survey among the general population, healthcare workers, physicians, and patients (Dec 2025, n=725) 31% prior awareness, 60% positive perception. Awareness & perception highest among physicians.

    https://journals.sagepub.com/doi/10.1177/17562848251399034
  26. Michael Harrop

    Video Is SIBO real? SIBO vs dysbiosis? Debunking the SIBO hypothesis | Small Intestinal Bacterial Overgrowth

    Of course. https://humanmicrobiome.info/obesity/ If you review the OP, you can see that there is no way to have or determine dysbiosis solely in the small intestine and not the large intestine. This is nonsense, not backed by any science that I'm aware of. Bile acid metabolism is a more...
  27. Michael Harrop

    Why are bacteria more likely to colonize when doing FMT compared to taking regular probiotics?

    You'd have to use the prefix filter: https://forum.humanmicrobiome.info/forums/microbiome-studies-articles/?prefix_id=6, and look through the wiki.
  28. Michael Harrop

    FMT Efficacy of oral and rectal administration of human faecal microbiota transplant (FMT) in human microbiota-associated mouse models (Dec 2025)

    https://www.nature.com/articles/s41598-025-32072-0
  29. Michael Harrop

    Why are bacteria more likely to colonize when doing FMT compared to taking regular probiotics?

    Don't you have a science degree? You constantly say the most unscientific things, demonstrating a fundamental lack of understanding of how basic evidence works. Overwhelmingly, the evidence contradicts your claims: https://humanmicrobiome.info/where-to-get-fmt/ The sources that process their...
  30. Michael Harrop

    Enhancing Should I take biofilm buster before FMT?

    There's not a lot of research on it, but there's a previous discussion & experiment: Improve FMT effectiveness with mucus and biofilm dissolver? N-acetyl cysteine (NAC)
  31. Michael Harrop

    FMT Recipients' native bacteria determine the outcome of FMT treatment in inflammatory bowel disease (Dec 2025, n=96) "remission rates were 82.4% for CD patients and 84.4% for UC patients"

    https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2600055 Those are unusually high remission rates.
  32. Michael Harrop

    Probiotics The Hype behind Probiotics (Dec 2025) Popular supplements with billions of “good” microbes really help only a few illnesses, research shows

    https://www.scientificamerican.com/article/the-hype-behind-expensive-probiotic-supplements/ Wow, misinformation: I wonder how much that was impacted by this:
  33. Michael Harrop

    Why are bacteria more likely to colonize when doing FMT compared to taking regular probiotics?

    It's covered in the probiotic guide: https://humanmicrobiome.info/probiotic-guide/
  34. Michael Harrop

    FMT Case Report: Fecal microbiota transplantation via capsules ameliorated clinical outcomes in a patient with multiple sclerosis (Nov 2025)

    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1678759/full
  35. Michael Harrop

    Testing We may finally know what a healthy gut microbiome looks like (Dec 2025, n=34,694) Gut micro-organisms associated with health, nutrition and dietary interventions

    https://www.newscientist.com/article/2508109-we-may-finally-know-what-a-healthy-gut-microbiome-looks-like/ https://www.nature.com/articles/s41586-025-09854-7 Ended with a big caveat there.
  36. Michael Harrop

    FMT Obesity-induced gut microbiota transplantation promotes the occurrence and development of hepatocellular carcinoma (Dec 2025, mice)

    https://www.tandfonline.com/doi/full/10.1080/20565623.2025.2599729
  37. Michael Harrop

    Study Do microplastics play a role in the pathogenesis of neurodegenerative diseases? Shared pathophysiological pathways for Alzheimer’s and Parkinson’s disease (review, Nov 2025)

    https://www.uts.edu.au/news/2025/12/five-ways-microplastics-may-harm-your-brain https://link.springer.com/article/10.1007/s11010-025-05428-3
  38. Michael Harrop

    Study Alarming surge in memory problems among young adults (Sep 2025, n=4.5 million) Rising Cognitive Disability as a Public Health Concern Among US Adults Trends From the Behavioral Risk Factor Surveillance System, 2013–2023

    https://www.sciencedaily.com/releases/2025/11/251102011158.htm https://www.neurology.org/doi/10.1212/WNL.0000000000214226
  39. Michael Harrop

    Study Hormone-disrupting chemicals from plastics shown to promote a chronic inflammatory skin condition (Nov 2025, n=20) Plastic associated endocrine disruptors reduce Nicastrin protein and potentiate inflammation in hidradenitis suppurativa skin disease

    https://medicalxpress.com/news/2025-12-hormone-disrupting-chemicals-plastics-shown.html https://www.nature.com/articles/s41467-025-65789-7
  40. Michael Harrop

    Article FDA Issues Warning About Imported Cookware That May Leach Lead: August 2025

    https://www.fda.gov/food/alerts-advisories-safety-information/fda-issues-warning-about-imported-cookware-may-leach-lead-august-2025 They have a table listing all the items, where they were sold, and photos of them. It looks like most of them are imported from India.
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