Recent content by SFBayFMT5

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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    It would be GREAT if more of the scientific community started talking about gut bacteria "for real" as you put it. But if the conclusions are what you are imagining (that specific species are "blamed" for diseases, as opposed to the lack of certain species causing diseases), then the cure that...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I have heard secondary reports of "Lactobacillus SIBO" where the only organism found in greater-than-normal numbers in the small intestine is a species of Lactobacillus (i.e. no significant elevation in any Enterobacteriaceae, Streptococcus, Bacteroides etc.) but never any literature. I...
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    FMT Microbiota Therapeutics Program (MTP) at the University of Minnesota (Jun 2025, UMN) Donor-centric administration of the stool donor program is vital to its feasibility and patient safety

    How would you know, since you only test your donors once? All Gezonde Darmflora donors except for DF6, their newest donor, have failed a stool test at one time or another, since they are tested monthly--however their overall probability of testing positive on any given test is low. Most months...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    I watched that video and I think I see what's going on. There's a lot of that in the science communication world. Basically, it's an alliance of science and a very "conservative" type of "alternative" health, where researchers come out and act as if they are starting "a revolution" when in fact...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    I think what we're running up against is a sort of "Catch 22" where most people don't try FMT because it's not readily available, and so then you don't have huge groups of people with success stories to tell who would sign petitions like this. Add to that the fact that even among those who DO...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    First the good: I REALLY appreciate the attempt to include a broader range of bacterial diversity (both genetic and functional) than the vast majority of other probiotics. We have one sugar fermenting lactic acid bacterium (Enterococcus), one "secondary fermenter" that utilizes the lactate...
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    FMT Fecal transplants: Study is a 'wake-up call' for the field as researchers identify unintended consequences. (Jun 2025, mice) Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects

    “There are microbes along the entire intestinal tract, and we just study predominately the last third of it (the colon),” DeLeon said. I've been saying this for years as well! That almost the entire research on the gut is focused on the large intestine, which in turn means largely on just two...
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    Early development In utero human intestine contains maternally derived bacterial metabolites (May 2025, n=21)

    From the very first sentence of the Methods section: "Placental and fetal samples were obtained from the University of Pittsburgh Biospecimen Core from electively terminated products of conception (14–23 weeks of gestation)" So indigo34 was correct--these were aborted fetuses.
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    Gezonde Darmflora Improvements to sleep, IBS, and weight from donor DF3 from Gezonde Darmflora

    Just so everyone here knows who might be thinking of trying her, DF3 is unfortunately no longer available How did you confirm a Lyme relapse? Did you have a recurrence of arthritis, a bull's eye rash, or some other specific Lyme symptom? In my experience, not only is it difficult to tell many...
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    FMT Fecal transplants: Study is a 'wake-up call' for the field as researchers identify unintended consequences. (Jun 2025, mice) Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects

    Recently posted by someone in another FMT group. https://www.cell.com/cell/abstract/S0092-8674(25)00564-1 "Fecal microbiota transplant (FMT) is an increasingly used intervention, but its suitability to restore regional gut microbiota, particularly in the small bowel (SB), must be questioned...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    MANY bacteria, including many probiotic strains, produce histamine. This is well studied--there are apparently probiotics that are supposed to contain low-histamine strains.
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Responded here: https://forum.humanmicrobiome.info/threads/thoughts-on-humanmicrobes-donor-problem.163/post-2528
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