Recent content by SFBayFMT5

It would be interesting to study the membrane properties of the bacteria that have >5% of their membrane lipids fluorinated due to culture in PFAS, e.g. in terms of ion leak, functioning of electron transport chain proteins, etc. Although they state that the concentration of PFAS they used did...

Have any of you heard of this guy and his story? https://www.nytimes.com/2017/02/04/business/his-doctors-were-stumped-then-he-took-over.html This guy is leading a drug repurposing initiative for rare diseases, after having discovered a treatment for his own rare disease. He managed to get...

I agree that the mucus-associated bacteria are probably more important than the luminal bacteria (which make up the majority of the poop) to transfer--especially since they're both more able to exchange metabolites directly with the host and have more access to oxygen from the gut wall to be...

I love the statement that the one pregnancy that occurred was "unrelated to treatment" :-) I'm not sure how well-established it is in fact that all women with a more diverse vaginal microbiome are at risk for reproductive complications. It is well-known that the diversity is correlated with...

For most people in the medical field, the risk/benefit analysis looks very different than from the POV of a desperate patient, or even a dispassionate scientist studying the microbiome in an abstract and/or theoretical manner. Their entire worldview is unfortunately clouded by thoughts of...

As far as I know, what first happened (at least in modern times) is doctors trying FMT for their patients in what were effectively informal clinical trials, when those patients had something like C. diff where there was no known cure that worked for the patients. At the time, since so few people...

You don't specify who "these companies" are, but I'm guessing you mean just general companies that are successful doing business in the US. I don't think you can compare FMT marketing to selling of something like computer games, AI, "life hack" gadgets, vacation rentals, or anything like that...

That's the first time I've seen mention of placing a GI catheter to allow repeated FMTs through a colonoscopy-like route. Clearly, having repeat colonoscopies seven days in a row each month for three months would never be allowed, and I guess for whatever reason they did NOT want to use capsules...

I think this is exactly it. And even people who are possibly worse in terms of objective sickness (if you can even measure that) are often sick in more visible and empathizable, "socially acceptable" ways, and see less of a gap between their current ability level and where they could be at if...

It's great that it worked so quickly for her. She's also lucky that doctors were already willing to help this family out and recommend FMT back in 2014. It's also a shame that someone her age was so sick already.

It's interesting here that increased serotonin is part of the pathology. This possibly has some relevance to people whose gut gets worse on SSRIs. My descent into the worst gut problems I've ever had started after being on 5-HTP for a little over 2 years. It was much worse even than where I...

From 00:35:20 in Casey Means' hearing: "The science is showing us, through amazing work in systems biology and network biology, that the physiologic causes of the vast majority of diseases... are connected by shared physiology and shared root causes." Then from 00:45:20: Dr. Jay Bhattacharya...

This seems like a very weak study, identifying a single bacterium that correlates with celiac disease and no attempt to follow it up to determine causality.

That IS sketchy. You may be wondering why I'm saying that now, given that I didn't consider it fishy when I learned he had neglected to inform me that one recipient had had a negative response to one donor. The difference is if it is a pattern. I take it for granted that for every provider of...

Thanks! I assumed that since I explained the background of the research and summarized the methods that including the abstract wasn't necessary. Now I know, I will paste the abstract in a quote if and when that research gets published in a regular journal.