Recent content by Michael Harrop

  1. Michael Harrop

    Other Early-Life Exposure to Certain Bacteria May Contribute to the Rising Incidence of Impact Early-Onset Colorectal Cancer (Apr 2025) Geographic and age variations in mutational processes in colorectal cancer

    https://www.infectiousdiseaseadvisor.com/news/early-life-exposure-to-certain-bacteria-may-impact-early-onset-colorectal-cancer-incidence/ https://www.nature.com/articles/s41586-025-09025-8
  2. Michael Harrop

    Article Your gut microbes might encourage criminal behavior. Is “My microbes made me do it” a valid legal defense? (May 2025)

    https://www.technologyreview.com/2025/05/09/1116211/gut-microbes-criminal-behavior/ I certainly agree. Which is one reason I think society will be quite utopian once we fix our biological defects.
  3. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Casey Means MD — Newsletter #35: My health wishlist for the next Administration https://www.caseymeans.com/learn/newsletter-35 The vast majority of it seems great. No mention of the microbiome or antibiotics though.
  4. Michael Harrop

    Other Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome (May 2025, mice) "The results suggest that targeting the gut microbiota may offer a strategy for preventing preeclampsia"

    https://www.nature.com/articles/s41467-025-58533-8
  5. Michael Harrop

    Study Biodegradable microplastics in mice gut trigger metabolic reprogramming, shedding light on safety concerns (May 2025) Incorporation of polylactic acid microplastics into the carbon cycle as a carbon source to remodel the endogenous metabolism of the gut

    https://medicalxpress.com/news/2025-05-biodegradable-microplastics-mice-gut-trigger.html https://www.pnas.org/doi/10.1073/pnas.2417104122 More bad news for bioplastics :(
  6. Michael Harrop

    Antibiotics Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors (May 2025)

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1589704/full A really interesting and well-done study of all the different ways antibiotics negatively impact the gut microbiome, beyond basic measurements like diversity and composition.
  7. Michael Harrop

    FMT Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis (May 2025, n=96) FMT from humans to mice confirmed the cognitive benefits were microbiota-dependent

    https://gut.bmj.com/content/early/2025/05/07/gutjnl-2025-335353
  8. Michael Harrop

    Causation Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice—An unbiased functional study (Feb 2025)

    https://medicalxpress.com/news/2025-05-twin-bacteria-small-intestine-play.html https://www.pnas.org/doi/10.1073/pnas.2419689122
  9. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Looks like another win for us: Trump Withdraws Surgeon General Nomination and Announces New Choice. The president said on social media that he would nominate Dr. Casey Means, confirming that he had withdrawn the nomination of Dr. Janette Nesheiwat, his first pick, a former Fox News contributor...
  10. Michael Harrop

    Causation Certain bacteria in breast tumour environments may fuel cancer spread (Feb 2025, mice) Identification of intratumoral bacteria that enhance breast tumor metastasis

    https://www.med.ubc.ca/news/certain-bacteria-in-breast-tumour-environments-may-fuel-cancer-spread/ https://journals.asm.org/doi/full/10.1128/mbio.03595-24
  11. Michael Harrop

    Article Consumer Reports warns of lead in popular gluten substitute. Cassava Flour, Chips, Bread, and More (May 2025)

    https://www.oregonlive.com/retail/2025/05/consumer-reports-warns-of-lead-in-popular-gluten-substitute.html https://www.consumerreports.org/health/food-contaminants/cassava-flour-chips-bread-more-contain-high-levels-of-lead-a7817220954/ Petition: Get toxic lead out of cassava products...
  12. Michael Harrop

    Probiotics Developing a probiotic cocktail that may help ward off dementia (Jan 2025) Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail. "Underlying mechanisms may differ depending on sex"

    https://medicalxpress.com/news/2025-05-probiotic-cocktail-ward-dementia.html https://www.nature.com/articles/s41598-024-84780-8
  13. Michael Harrop

    Early development In utero human intestine contains maternally derived bacterial metabolites (May 2025, n=21)

    https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02110-0
  14. Michael Harrop

    Study Heart disease deaths worldwide linked to chemical widely used in plastics (Apr 2025) Phthalate exposure from plastics and cardiovascular disease: global estimates of attributable mortality and years life lost

    https://medicalxpress.com/news/2025-04-heart-disease-deaths-worldwide-linked.html https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00174-4/fulltext
  15. Michael Harrop

    Article New NIH office to reduce use of animals in research, shuts down final beagle lab. Agency plans to promote alternative methods and address “bias” toward animal studies in grant review (Apr 2025)

    https://www.science.org/content/article/new-nih-office-reduce-use-animals-research https://www.shorenewsnetwork.com/2025/05/05/nih-shuts-down-final-beagle-lab-ending-decades-of-painful-dog-experiments/ I have mixed feelings about that. The gut microbiome is a major factor in why animal...
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