Recent content by Michael Harrop

  1. Michael Harrop

    Healthcare system Incoming trump admin with RFK signals new start for FDA

    This video was a good reminder of another possible reason Congresspeople have done nothing about this -- personal investments in the stock market (the pharmaceutical industry). https://www.youtube.com/watch?v=BsrAZ0gnkPo
  2. Michael Harrop

    Oral microbiome - Streptococcus overgrowth (test results)

    It sounds like you didn't read the stickied post: https://forum.humanmicrobiome.info/threads/before-you-post-or-comment-here-please-review-the-testing-page-of-the.24/
  3. Michael Harrop

    STICKY Before you post or comment here, please review the Testing page of the wiki to understand what these tests can and cannot do, and what kind of feedback you can expect to receive. Marketing is not allowed.

    Related thread: FMT, donor-matching, screening for specific microbes, and pre-treatment/eradication. "Killing things off" vs suppression & ecosystem restoration.
  4. Michael Harrop

    FMT Fecal microbiota transplantation improves bile acid malabsorption in patients with inflammatory bowel disease: results of microbiota and metabolites from two cohort studies (Sept 2025)

    https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-04353-y I think n=106, but they're using the word "pairs" confusingly. I don't think they gave the 24 healthy controls FMT. Donors: Doesn't say how many donors were used. Results:
  5. Michael Harrop

    Antibiotics Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes (Aug 2025) "We find that antibiotic preconditioning reduces efficiency for uptake of CMT-specific strains. Antibiotics introduce uncontrolled variance in the resulting microbiome composition"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1632210/full Another piece of evidence opposing antibiotics prior to FMT.
  6. Michael Harrop

    FMT Obese teens given healthy gut bacteria show lasting drop in diabetes risk (Aug 2025, n=55) Long-term health outcomes in adolescents with obesity treated with faecal microbiota transplantation: 4-year follow-up

    https://medicalxpress.com/news/2025-08-obese-teens-healthy-gut-bacteria.html https://www.nature.com/articles/s41467-025-62752-4 New Zealand group. This is a follow-up to their "gut bugs" study...
  7. Michael Harrop

    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    By "can't", do you mean "shouldn't be"? There's info in this thread: https://forum.humanmicrobiome.info/threads/microbiota-therapeutics-program-mtp-at-the-university-of-minnesota-jun.1089/ - you can continue there since it's off-topic here.
  8. Michael Harrop

    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    I think this is a continued misunderstanding of the situation. There is already heavy regulation that the UMN stool bank complies with. The issue is that the person running the stool bank lacks the judgment and motivation to acquire safe and effective donors.
  9. Michael Harrop

    Study Mount Sinai study supports evidence that prenatal acetaminophen use may be linked to increased risk of autism and ADHD (Aug 2025, review) Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology

    Yes, ultimately, the problem is unhealthy people using their bodies to create other people. And the primary solution is FMT.
  10. Michael Harrop

    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    As I said, because they know about it and claim they want to make cures available and end chronic disease. The public doesn't need to be well-informed for the FDA, NIH, or HHS to do something about a relatively unknown treatment. There is nothing else that comes close to the power & potential of...
  11. Michael Harrop

    FMT Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial (Aug 2025, n=20)

    I'm always skeptical of adverse event tracking, but it doesn't appear they used former cancer patients as donors for this study. It appears that they used regular, healthy donors. In fact, this study provides support for the notion that you don't need to use other cancer patients as donors.
  12. Michael Harrop

    Causation Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study (Aug 2025) "Our study revealed a significant causal impact of five GM genera, 10 metabolites, two metabolite ratios, and 22 immune cells"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1620449/full
  13. Michael Harrop

    Study Chronic Exposure to Microplastics Induces Blood–Brain Barrier Impairment, Oxidative Stress, and Neuronal Damage in Rats (Jun 2025)

    https://link.springer.com/article/10.1007/s12035-025-05157-0 https://www.psypost.org/chronic-exposure-to-microplastics-impairs-blood-brain-barrier-and-damages-neurons/
  14. Michael Harrop

    FMT Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial (Aug 2025, n=19) "significant reduction in hepatic encephalopathy severity"

    https://www.mdpi.com/2077-0383/14/17/5981 Donors:
  15. Michael Harrop

    FMT Colonoscopic fecal microbiota transplantation for Mild-to-Moderate Parkinson’s Disease: A randomized controlled trial (Aug 2025, n=30) "alleviates motor and non-motor symptoms"

    https://www.sciencedirect.com/science/article/pii/S0889159125003216 Donor:
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