Recent content by Michael Harrop

  1. Michael Harrop

    Article The Poop Broker. Michael Harrop started a booming underground market for human feces. But something smells off about his product. (May 2024)

    Yeah it was an odd article. There were so many other interesting things that could have been covered. For example, the journalist noticed a trend of most recipients ordering FMT due to being harmed by antibiotics. I mentioned to the journalist that there are lots of laypeople who exhibit hostile...
  2. Michael Harrop

    Article The Poop Broker. Michael Harrop started a booming underground market for human feces. But something smells off about his product. (May 2024)

    I was thinking about this in the context of the media always complaining that they're dying and can't afford to fund themselves. For the past two days there have been dozens of articles in my news feed covering the same trivial story about one person doing DIY FMT from their boyfriend. Somehow...
  3. Michael Harrop

    Article The Poop Broker. Michael Harrop started a booming underground market for human feces. But something smells off about his product. (May 2024)

    https://slate.com/life/2024/05/fecal-transplant-fmt-c-diff-microbiome-poop-black-market.html Kind of an odd article. Amusing, seemingly agenda-driven, occasionally deceptive, but not all bad. I'm curious what impact this article will have. Will it be better or worse than the "complete silence"...
  4. Michael Harrop

    Study A long-term ketogenic diet accumulates aged cells in normal tissues (May 2024, mice) Ketogenic diet induces p53-dependent cellular senescence in multiple organs

    https://medicalxpress.com/news/2024-05-term-ketogenic-diet-accumulates-aged.html https://www.science.org/doi/10.1126/sciadv.ado1463
  5. Michael Harrop

    Article UK governments announce ban on wet wipes containing plastic (Apr 2024) "Wet wipes containing plastic are polluting our waterways and causing microplastics to enter the environment". 95% of respondents agreed or strongly agreed.

    https://www.circularonline.co.uk/news/uk-governments-announce-ban-on-wet-wipes-containing-plastic/ Nice to see the public and government supportive and taking steps to reduce plastic waste. Petition your own government to do the same!
  6. Michael Harrop

    Microbioma Microbioma.org full history and review

    It appears that the Microbioma guys successfully abused Reddit's automated systems to get the /r/Microbioma subreddit erroneously banned for spam https://web.archive.org/web/20240518081007/https://old.reddit.com/r/Microbioma/. They may be successful in getting Reddit to hand the sub over to them...
  7. Michael Harrop

    Mucosal microbiota transplant, clearing the gut mucosa prior to FMT

    The OP covered a unique method that one study used for diabetes patients. The next comment covers the possibility of using NAC. A colon cleanse doesn't seem sufficient https://humanmicrobiome.info/fmt/#before-the-procedure.
  8. Michael Harrop

    Mucosal microbiota transplant, clearing the gut mucosa prior to FMT

    Related threads: Improve FMT effectiveness with mucus and biofilm dissolver? N-acetyl cysteine (NAC) FMT engraftment Strategies To Increase The Effectiveness Of FMT
  9. Michael Harrop

    Mucosal microbiota transplant, clearing the gut mucosa prior to FMT

    I posted about this a few years ago elsewhere and I'm copying all the info here for easy discussion. "While fecal microbiota is partially normalized by extended co-housing, mucosal communities associated with the proximal colon and terminal ileum remain stable and distinct". Comparison of...
  10. Michael Harrop

    Improve FMT effectiveness with mucus and biofilm dissolver? N-acetyl cysteine (NAC)

    I remember reading something on this topic but my memory is terrible right now and I can't remember exactly what it was. But this seems like something that should be tested in animal models first. I covered the possibility of a "mucosal microbiota transplant" in my FMT roadmap proposal. I...
  11. Michael Harrop

    FMT Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice (Apr 2024)

    There appears to be an impact on lifespan, but not that much research on it yet https://humanmicrobiome.info/aging/. Most of the research looks focused on healthspan.
  12. Michael Harrop

    Antibiotics Commonly used antibiotic brings more complications, death in the sickest patients (May 2024, n=7569) Mortality of Patients With Sepsis Administered Piperacillin-Tazobactam vs Cefepime

    https://www.eurekalert.org/news-releases/1044459 https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2818278
  13. Michael Harrop

    FMT Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice (Apr 2024)

    https://www.aginganddisease.org/EN/10.14336/AD.2024.0321
  14. Michael Harrop

    Doxycycline Advice

    https://humanmicrobiome.info/faq/ https://humanmicrobiome.info/probiotic-guide/ In my opinion (+ https://humanmicrobiome.info/antibiotics/), nothing but FMT will reverse that damage.
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