Recent content by GutBrainAxis

Are there any bacteria mentioned in the below paragraph that might be available to purchase in the near future? How many of the bacteria mentioned might become popular probiotics? https://www.mdpi.com/2073-4409/12/13/1735 The adult gut microbiota is composed mainly of the phyla Firmicutes...

I definitely seem to react very strongly to garlic and/or oregano. I wonder if finding out what garlic and oregano do could yield a clue as to what the story is with my gut. I'm referring to supplements here; I'm not talking about eating the actual herbs.

This is interesting, right? https://royalsocietypublishing.org/doi/full/10.1098/rstb.2017.0286 Early life is a critical period for gut colonization [51], the establishment of the HPA axis, as well as neurodevelopment ([4] and references therein), and growing evidence suggests these systems...

1: I got a great reaction from taking garlic and oregano. There's no way to guess why those two things might be helping me, though, right? Those two things combat pathogenic bacteria, but they do various things. 2: Is it worth learning about "nitrogen metabolism"? What are the other major...

Is there any literature on the idea that taking too high a dose of probiotics could produce SIBO? I don't know what is supposed to cause SIBO or whether there are even any leading hypotheses about what causes it. Why isn't "Turicibacter sanguinis" available as a probiotic? Just curious...

I'd never heard of this product: https://pmc.ncbi.nlm.nih.gov/articles/PMC5138452/ From the presented overview of Symbioflor E. coli research, which to the knowledge of the author covers all available peer-reviewed literature on this product, it is obvious that the research conducted is...

Is it possible that any of the bacteria types included in this ( https://aor.ca/product/probiotic-3 ) product are actually unhelpful or even harmful? One tends to think that they wouldn't be selling X unless X were at least safe and hopefully effective too. From the above link, see this...

Is there any literature on the combination of antihistamines (H1, H2, and both H1 and H2) and probiotics? Is there a potential ambiguity whereby you think you have a gut-biota problem but actually you have an immune-system problem? For example, someone might take an anti-inflammatory drug (like...

I haven't been on this forum for a long time. See below some questions. 1: What are the odds that it will turn out that the gut biota are not as impactful as many thought? To what extent is there unwarranted "hype" around gut biota? See here, for example...

I wouldn't be surprised if addressing gut-biota problems fixed any psychiatric condition. Of course, a big question is whether there will be any clinical trials that will take a gut-biota treatment (in this case, for bipolar) from anecdote to something more than anecdote. Do you know any trials...

Doesn't seem like it's possible to buy an L-DOPA supplement. You can only get the one that isn't "earmarked" for production of DA and NE, right?

1: I took some 5-HTP last night and it made a huge (!!!) difference. I really hope that this quite miraculous improvement doesn't go away. 2: When was the last time you took some 5-HTP? Baffling to me why it stopped working for you; hope you can get the effect back. 3: What can one say about...

1: Do you guys know a lot about butyrate and butyrate supplementation? See this excellent paper: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.893567/full. The paper says interesting things about butyrate, including the following: 2: I took some butyrate pills...

1: I get a huge reaction from melatonin. That's why I'm interested in agomelatine, which apparently has a superior melatonin-receptor effect to melatonin's, though I can't remember what exactly the advantage is supposed to be. 2: Melatonin is a fascinating thing...see this paper here...

Thanks for the excellent points. I appreciate it. 1: If you don't mind me asking, what are your credentials? You seem to have professional knowledge. 2: What do you think about Pendulum's products? Some of their products seem to be redundant. I think that the "Metabolic Daily" one contains...