I've done a small amount of research and found out that the human body has separate microbiota in the stomach, small intestine and lungs as well as the colon. My question is why focus on the colon microbiota, wouldn't it be better to transplant microbes from every part of the body that they are found in? Is it possible to safely transplant microbes from those parts? and how would that work? I'm also wondering if anyone has figured out an effective way to clear the microbiome prior to FMT?
Why FMT specifically? Why focus on the colon microbiota, wouldn't it be better to transplant microbes from every part of the body that they are found in? Other
- Thread starter ThadeusW
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ButterflyShoeMill42
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I just did a colonoscopy and inserted into my colon. If there's a better way. I don't know how to do it. Even if I am not 100%,I am close to it and doing very well. I assume my donors sample had bacteria from the entire digestive to tract and that my body would use what it could.
Aim for NaN
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Not all species can survive every environment.
Michael Harrop
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Poop contains microbes from the entire digestive tract, including oral microbes.
There are different percentages of microbes at different body sites due to the different environments. [1]
When you transplant stool into another body site, the percentages of microbes will change due to the environmental influences.
The gut microbiome regulates other body sites' microbiomes. [1]
Poop is easy to collect and transplant, and seems to be a diverse & rich sample. The difficulty of collecting & transplanting microbes from each body site is much greater than FMT, and there's little evidence to suggest it's needed.
There are different percentages of microbes at different body sites due to the different environments. [1]
When you transplant stool into another body site, the percentages of microbes will change due to the environmental influences.
The gut microbiome regulates other body sites' microbiomes. [1]
Poop is easy to collect and transplant, and seems to be a diverse & rich sample. The difficulty of collecting & transplanting microbes from each body site is much greater than FMT, and there's little evidence to suggest it's needed.
This is a separate topic covered here: https://forum.humanmicrobiome.info/forums/fecal-microbiota-transplant-fmt/?prefix_id=64