For anyone who has done FMT, did you have worsening symptoms in the few days after? Outcomes 

Prodigyev

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Nov 29, 2025
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I did my fist FMT a few days ago. I think I’m experience more brain fog today…is this a bad sign? Maybe my biome is shifting a bit? Maybe I’m coping?
 
In my experience, some donors can trigger an initial day-or-so of worsening symptoms before seeing subsequent improvements. With bad donors, they can worsen symptoms and cause new ones, and the symptoms don't go away.

It can be difficult to immediately determine which is which. Adequate learning & donor selection beforehand are key.

More info: https://www.humanmicrobes.org/fmt-clinician-guidance
 
Nope. My sleep pattern changed immediately because my donor was from Europe, but it took about 3 days calm down and then was much improved, better deep sleep and REM sleep. I don't remember anything bad like bloating or gas or pain, just that my Bristol stool quality changed from constipated to three to four.
 
In my experience, some donors can trigger an initial day-or-so of worsening symptoms before seeing subsequent improvements. With bad donors, they can worsen symptoms and cause new ones, and the symptoms don't go away.

It can be difficult to immediately determine which is which. Adequate learning & donor selection beforehand are key.

More info: https://www.humanmicrobes.org/fmt-clinician-guidance
Thank you. I read online people with severe issues, and people who have antibiotic resistant bacteria might need multiple FMT’s before they see improvement. I’m going to do more.
 
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