synthetic fmt

  1. Michael Harrop

    FMT A synthetic microbiome therapy suppresses C. diff infection without antibiotics (Mar 2025) A designed synthetic microbiota provides insight to community function in Clostridioides difficile resistance

    https://medicalxpress.com/news/2025-02-synthetic-microbiome-therapy-suppresses-bacterial.html https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(25)00055-1
  2. Michael Harrop

    FMT Safety and Efficacy of Fecal Microbiota, Live-jslm (REBYOTA®), for the Prevention of Recurrent Clostridioides difficile Infection in Participants With Inflammatory Bowel Disease in PUNCH CD3-OLS (Jan 2025, n=793) 4.2% serious adverse events, 79% success rate.

    https://academic.oup.com/ibdjournal/advance-article/doi/10.1093/ibd/izae291/7979239 Subgroup of this study: PUNCH CD3-OLS: a phase 3 prospective observational cohort study to evaluate the safety and efficacy of fecal microbiota, live-jslm (REBYOTA) in adults with recurrent Clostridioides...
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