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  1. Michael Harrop

    Diet Gluten sensitivity linked to gut–brain interaction, not gluten itself (Oct 2025, review) Non-coeliac gluten sensitivity

    https://medicalxpress.com/news/2025-10-gluten-sensitivity-linked-gutbrain-interaction.html https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01533-8/abstract
  2. Michael Harrop

    FMT The Super-Donor Phenomenon in Fecal Microbiota Transplantation (Jan 2019, review)

    https://www.frontiersin.org/articles/10.3389/fcimb.2019.00002/full An important paper to have submitted here. Unfortunately, the authors of this review didn't bother to attempt to find a super-donor for their FMT trial...
  3. Michael Harrop

    FMT Fecal Transplant From The Rock Causes Mysterious Side Effects in Man (Oct 2025)

    https://the-peel.com/article/1723/ This doesn't seem to be a real story. See their "about" page: https://the-peel.com/about/ Their bluesky says "on the mission to deliver news before it happens".
  4. Michael Harrop

    FMT Scientists develop a way to track donor bacteria after fecal microbiota transplants (Oct 2025) Long-read metagenomics for strain tracking after faecal microbiota transplant

    https://medicalxpress.com/news/2025-10-scientists-track-donor-bacteria-fecal.html https://www.nature.com/articles/s41564-025-02164-8
  5. Michael Harrop

    FMT Shaping the future of probiotics, live biotherapeutic products, and fecal microbiota transplantation: 30 scientific recommendations from the CHINAGUT Conference (Oct 2025)

    https://onlinelibrary.wiley.com/doi/10.1002/imt2.70083 This is incredibly depressing. Not a single mention of donor quality, and they're promoting the failed & inadequate stool bank model.
  6. Michael Harrop

    FVT Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial (Sep 2025, n=138) "supporting the crucial role of live microbes in mediating clinical efficacy"

    https://www.thelancet.com/journals/langas/article/PIIS2468-1253%2825%2900190-6/abstract A previous study indicated that a sterile fecal filtrate was effective for C. diff. https://humanmicrobiome.info/fmt/#sterile-fecal-filtrate This study says otherwise.
  7. Michael Harrop

    Article Protein Powders and Shakes Contain High Levels of Lead. Consumer Reports investigation (Oct 2025)

    https://www.consumerreports.org/lead/protein-powders-and-shakes-contain-high-levels-of-lead-a4206364640/
  8. Michael Harrop

    Video RFK Jr. hosts roundtable on long COVID (Sep 18, 2025)

    https://www.hhs.gov/press-room/hhs-secretary-kennedy-long-covid-roundtables-action.html https://www.youtube.com/watch?v=NzGbNCAzkcI This video makes this administration seem like a big fucking scam. All the big players in this video know about the gut microbiome and FMT, including Senator...
  9. Michael Harrop

    FMT Assessing healthcare workers as potential stool donors for faecal microbiota transplantation: a cross-sectional study of antimicrobial-resistant gut bacteria and enteropathogenic microorganisms (Sep 2025, n=106) "supports the inclusion of HCWs as potential stool donors for FMT"

    https://www.journalofhospitalinfection.com/article/S0195-6701(25)00277-4/abstract Previous guidelines have recommended against using healthcare workers as donors. This study indicates otherwise.
  10. Michael Harrop

    Study Obesity during pregnancy doubles autism risk and increases ADHD risk by up to 57% (Sep 2024, n=3.6m mother-child pairs) Associations between maternal preconception and pregnancy adiposity and neuropsychiatric and behavioral outcomes in the offspring: A systematic review and meta-analysis

    https://www.unisa.edu.au/media-centre/Releases/2024/obesity-in-mums-doubles-the-risk-of-autism-in-babies/ https://www.sciencedirect.com/science/article/pii/S0165178124004347 Relevant due to the recent RFK/Trump announcement blaming Tylenol. Rhonda Patrick alerted me to this.
  11. Michael Harrop

    FMT Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-ENEMA FMT Trial) (Sep 2025, n=45) "Higher clinical response and quality of life in both FMT groups than placebo"

    https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1648944/full Standard/poor donor quality.
  12. Michael Harrop

    Article Trump admin links Tylenol/acetaminophen use in pregnancy to increased risk of autism despite mixed studies (Sep 2025)

    https://apnews.com/article/tylenol-cause-autism-trump-kennedy-0847ee76eedecbd5e9baa6888b567d66 https://www.pbs.org/newshour/politics/trump-administration-suggests-acetaminophen-during-pregnancy-causes-autism-experts-say-a-link-between-the-two-is-unproven This was their "big September...
  13. Michael Harrop

    FMT Repeated faecal microbiota transplantation for individuals with type 1 diabetes and gastroenteropathy (Sep 2025, n=17) "Participant satisfaction was high, with 86% reporting considerable benefits"

    https://link.springer.com/article/10.1007/s00125-025-06544-x
  14. Michael Harrop

    FMT Gut microbiota characteristics and therapeutic effects of fecal microbiota transplantation in children with autism spectrum disorder in central China: a combined cross-sectional and prospective study (Sep 2025, n=25) "significant improvements to core ASD symptoms and GI comorbidities"

    https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1648471/full I don't see how many donors were used. It's good that they age-matched.
  15. Michael Harrop

    Other Non-antibiotic medications leave lasting mark on gut microbiome, even years after use (Sep 2025) A hidden confounder for microbiome studies: medications used years before sample collection

    https://medicalxpress.com/news/2025-09-medications-gut-microbiome-years.html https://journals.asm.org/doi/10.1128/msystems.00541-25
  16. Michael Harrop

    Article Trump admin releases long awaited MAHA roadmap. The new strategy stops short of surprise regulations and leaves pesticides alone (Sep 2025) The Make Our Children Healthy Again Strategy Report

    https://www.whitehouse.gov/maha/ https://www.whitehouse.gov/wp-content/uploads/2025/09/The-MAHA-Strategy-WH.pdf https://www.usda.gov/about-usda/news/press-releases/2025/09/09/maha-commission-unveils-sweeping-strategy-make-our-children-healthy-again...
  17. Michael Harrop

    Causation Gut microbial production of imidazole propionate drives Parkinson’s pathologies (Sep 2025)

    https://www.nature.com/articles/s41467-025-63473-4
  18. Michael Harrop

    FMT Fecal Microbiota Transplantation by Rectal Enema Improves Short-Term Insulin Resistance in Metabolic Syndrome: A Pilot Randomized Controlled Trial (May 2025, n=18)

    https://www.jomes.org/journal/view.html?doi=10.7570/jomes25014
  19. Michael Harrop

    Early development Establishment of the early gut microbiota in vaginally delivered infants: the influence of maternal gut microbiota outweighs vaginal microbiota (Aug 2025, 26 mother-infant pairs)

    https://journals.asm.org/doi/10.1128/spectrum.01775-25
  20. Michael Harrop

    Article Studies deliver new blow to cancer microbiome literature—and offer a way forward. Two analyses of microbial DNA in tumor samples aim to put controversy-riddled field back on track (Sep 2025, Micronoma)

    https://www.science.org/content/article/studies-deliver-new-blow-cancer-microbiome-literature-and-offer-way-forward I'm posting this because Rob Knight is a major figure in the microbiome world. Martin J. Blaser, M.D. was on their scientific advisory board...
  21. Michael Harrop

    FMT Fecal microbiota transplantation improves bile acid malabsorption in patients with inflammatory bowel disease: results of microbiota and metabolites from two cohort studies (Sept 2025)

    https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-04353-y I think n=106, but they're using the word "pairs" confusingly. I don't think they gave the 24 healthy controls FMT. Donors: Doesn't say how many donors were used. Results:
  22. Michael Harrop

    Antibiotics Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes (Aug 2025) "We find that antibiotic preconditioning reduces efficiency for uptake of CMT-specific strains. Antibiotics introduce uncontrolled variance in the resulting microbiome composition"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1632210/full Another piece of evidence opposing antibiotics prior to FMT.
  23. Michael Harrop

    FMT Obese teens given healthy gut bacteria show lasting drop in diabetes risk (Aug 2025, n=55) Long-term health outcomes in adolescents with obesity treated with faecal microbiota transplantation: 4-year follow-up

    https://medicalxpress.com/news/2025-08-obese-teens-healthy-gut-bacteria.html https://www.nature.com/articles/s41467-025-62752-4 New Zealand group. This is a follow-up to their "gut bugs" study...
  24. Michael Harrop

    Causation Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study (Aug 2025) "Our study revealed a significant causal impact of five GM genera, 10 metabolites, two metabolite ratios, and 22 immune cells"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1620449/full
  25. Michael Harrop

    Study Chronic Exposure to Microplastics Induces Blood–Brain Barrier Impairment, Oxidative Stress, and Neuronal Damage in Rats (Jun 2025)

    https://link.springer.com/article/10.1007/s12035-025-05157-0 https://www.psypost.org/chronic-exposure-to-microplastics-impairs-blood-brain-barrier-and-damages-neurons/
  26. Michael Harrop

    FMT Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial (Aug 2025, n=19) "significant reduction in hepatic encephalopathy severity"

    https://www.mdpi.com/2077-0383/14/17/5981 Donors:
  27. Michael Harrop

    FMT Colonoscopic fecal microbiota transplantation for Mild-to-Moderate Parkinson’s Disease: A randomized controlled trial (Aug 2025, n=30) "alleviates motor and non-motor symptoms"

    https://www.sciencedirect.com/science/article/pii/S0889159125003216 Donor:
  28. Michael Harrop

    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    https://jamanetwork.com/journals/jama/fullarticle/2835314 Subsections: Unleashing AI Healthier Food for Children Harnessing Big Data Financial Toxicity Sounds like more useless, distracting BS, and that they have no plans to do anything about FMT.
  29. Michael Harrop

    Study Mount Sinai study supports evidence that prenatal acetaminophen use may be linked to increased risk of autism and ADHD (Aug 2025, review) Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology

    https://www.eurekalert.org/news-releases/1094641 https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0
  30. Michael Harrop

    Study The Lancet Countdown on health and plastics (2025) "Plastics are a grave, growing, and under-recognised danger to human and planetary health"

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01447-3/abstract
  31. Michael Harrop

    FMT Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial (Aug 2025, n=20)

    https://jitc.bmj.com/content/13/8/e012659
  32. Michael Harrop

    FMT Consecutive fecal microbiota transplantation for metabolic dysfunction-associated steatotic liver disease: a randomized controlled trial (Aug 2025, n=20) "FMT did not significantly affect hepatic steatosis, glucose tolerance, liver biochemistry, or gut microbiota signatures"

    https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2541035#abstract Donors: More evidence that the stool bank model and the standard donor criteria are non-viable. Zero results for "symptoms" or "adverse events". So it doesn't appear that they were tracked at all. It's incredible...
  33. Michael Harrop

    Causation Newly discovered gut bacteria proteins influence hormones, metabolism and bone density (Jul 2025, mice) Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

    https://medicalxpress.com/news/2025-07-newly-gut-bacteria-proteins-hormones.html https://www.nature.com/articles/s41564-025-02064-x
  34. Michael Harrop

    Article Top FDA Official Resigns Under Pressure (Jul 2025) After turning down several new drugs and restricting use of another, Dr. Vinay Prasad drew the ire of the right-wing influencer Laura Loomer and others

    https://www.nytimes.com/2025/07/29/health/vinay-prasad-fda-resigns-loomer.html https://archive.ph/JEveK This is big, but I'm not sure if it's good or bad for FMT. Based on the article, he seems like the kind of person who would work to make FMT available, but then again, maybe not, and he...
  35. Michael Harrop

    Article FDA names former pharmaceutical company executive, Dr. George Tidmarsh, to oversee US drug program, CDER (2025)

    https://apnews.com/article/fda-drugs-trump-makary-george-tidmarsh-88471eab7dcaf1ab8cc4dd2491218120 No mention of scrutinizing the safety of antibiotics, even though Dr. Makary is well-informed on their harms and their contribution to the chronic disease crisis.
  36. Michael Harrop

    Study Patient Advocacy Organizations: Institutional Conflicts of Interest, Trust, and Trustworthiness (2013)

    https://pmc.ncbi.nlm.nih.gov/articles/PMC4107906/ I've spent the past 10 months living in my car in DC, visiting the Congressional offices most days. I've seen lots of Patient Advocacy Orgs (PAOs) here. A few Congresspeople recommended I contact PAOs. I was already contacting every PAO I came...
  37. Michael Harrop

    Aging Identification of gut microbiota causally associated with aging and longevity and mediation roles of the cerebrospinal fluid proteins: proteomic genetic evidence from Mendelian randomization (Jul 2025)

    https://link.springer.com/article/10.1007/s11357-025-01794-4
  38. Michael Harrop

    Other Previously undetectable biomarkers in gut microbiome may predict 'invisible' chronic fatigue syndrome, long COVID (Jul 2025, n=249) AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome

    https://medicalxpress.com/news/2025-07-previously-undetectable-biomarkers-gut-microbiome.html#google_vignette https://www.nature.com/articles/s41591-025-03788-3
  39. Michael Harrop

    Antibiotics Influence of perinatal antibiotic on neonatal gut microbiota: a prospective cohort study (Jul 2025, n=182) "perinatal antibiotic exposure is associated with significant changes in the neonatal gut microbiota, potentially increasing the pathogenic microbiota"

    https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-025-05907-y
  40. Michael Harrop

    Probiotics Probiotics Can Help or Hinder Gut Recovery After Antibiotic Treatment (Jul 2025, mice) Differential modulation of post-antibiotic colonization resistance to Clostridioides difficile by two probiotic Lactobacillus strains

    https://news.ncsu.edu/2025/07/probiotics-can-help-or-hinder-gut-recovery-after-antibiotic-treatment/ https://journals.asm.org/doi/10.1128/mbio.01468-25
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