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  1. Michael Harrop

    Other Scientists identify bacterial glycogen as a gut trigger behind ALS and dementia (Jan 2026) C9orf72 in myeloid cells prevents an inflammatory response to microbial glycogen

    https://www.sciencedaily.com/releases/2026/04/260408225944.htm https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01678-X
  2. Michael Harrop

    FVT Fecal virome transplantation attenuates arthritis in mice by remodeling gut ecology, systemic tryptophan metabolism, and innate immune responses (Apr 2026)

    https://www.nature.com/articles/s41522-026-00980-2
  3. Michael Harrop

    Other Bacteria are weaving forever chemicals directly into their cell membranes (Mar 2026) Bacteria covalently incorporate polyfluoroalkyl carboxylates into membrane lipids

    https://phys.org/news/2026-04-bacteria-chemicals-cell-membranes.html https://www.nature.com/articles/s41564-026-02301-x
  4. Michael Harrop

    Article EPA, HHS Announce Historic Actions to Protect Americans from Microplastics and Safeguard Drinking Water. ARPA-H launches groundbreaking, $144 million program to combat microplastics in the human body (Apr 2026)

    https://www.epa.gov/newsreleases/epa-hhs-announce-historic-actions-protect-americans-microplastics-and-safeguard https://www.hhs.gov/press-room/arpa-h-launches-groundbreaking-144-million-program-combat-toxic-microplastics-human-body.html...
  5. Michael Harrop

    Diet Stools suggest why Papua New Guineans on low-protein diet are muscular. Excreta-related research at the University of Tokyo (Apr 2026)

    https://www.u-tokyo.ac.jp/focus/en/features/z1304_00300.html
  6. Michael Harrop

    Vagina Vaginal microbiota transplantation for treatment of vaginal dysbiosis without the use of antibiotics: a double-blind, randomised controlled trial in women with vaginal dysbiosis (Mar 2026, n=49) "VMT without antibiotics did not significantly improve microbiome conversion in this trial"

    https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00222-8/fulltext
  7. Michael Harrop

    Study Breakdown products from 'eco-friendly' plastics impede fetal development in mice (Mar 2026) Oligomeric lactic acid nanoplastics induce intrauterine growth restriction in mice by disrupting GATA2-mediated placental vascular development

    https://medicalxpress.com/news/2026-03-breakdown-products-eco-friendly-plastics.html https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003676
  8. Michael Harrop

    FMT Faecal microbiota transplant for chronic norovirus infection: a case report of donor microbiota engraftment without clinical success (Mar 2026)

    https://academic.oup.com/gastro/article/doi/10.1093/gastro/goag015/8512970
  9. Michael Harrop

    FMT Her son needed a fecal transplant for a fearsome C. diff infection. Getting one required a tortuous journey. Stricter FDA stool bank rules made the treatment harder to find (Mar 2026)

    https://www.statnews.com/2026/03/23/c-diff-fda-drug-approval-access-paradox-fecal-transplants/
  10. Michael Harrop

    FMT Faecal Microbiota Transplantation Improves Outcomes in Depression (Mar 2026, n=46) A study on the efficacy and safety of fecal microbiota transplantation as an adjunctive therapy for treating depressive episodes

    https://www.emjreviews.com/neurology/news/faecal-microbiota-transplantation-improves-outcomes-in-depression/ https://www.nature.com/articles/s41598-026-41801-y
  11. Michael Harrop

    Other Popularity and acceptance of FMT. Who is to blame for why FMT will never be available? Ignorance, laziness, and apathy of the general public? How to motivate people to take action?

    This is completely erroneous. Chronic disease and poor health already afflict the vast majority of the population. They can't try FMT because safe and effective donors are not available, and will never be because people are too ignorant and lazy to do anything to make them so. They're not...
  12. Michael Harrop

    FMT Gut microbiota modulation via repeated donor fecal transplantation improves motor and gastrointestinal symptoms in drug-naïve Parkinson’s disease: a randomized phase 2 trial (Mar 2026, n=72)

    https://www.nature.com/articles/s41392-026-02604-9
  13. Michael Harrop

    10-year-old Emma puts severe Ulcerative Colitis in remission with DIY FMT from her mom (2013)

    https://www.youtube.com/watch?v=E-5-QOjTkEs A second video with a little more info: https://www.youtube.com/watch?v=xLIndT7fuGo It references this blog, but most of the saves are unavailable https://web.archive.org/web/20130113144423/http://thepowerofpoo.blogspot.com/ Donor: Mother. The...
  14. Michael Harrop

    Aging Scientists Tried to Age Young Ovaries with Old Microbes but Accidentally Made Them More Fertile (Mar 2026) Estropausal gut microbiota transplant improves measures of ovarian function in adult mice

    https://www.zmescience.com/ecology/animals-ecology/young-ovaries-old-microbes/ https://www.nature.com/articles/s43587-026-01069-3
  15. Michael Harrop

    Rod Clair does successful FMT from his wife for diverticular disease, IBS, severe gastritis, chronic fatigue, and more (Dec 2021, fecal microbiota transplant)

    https://www.youtube.com/watch?v=pN1VV_zauDU Her stool quality looks pretty good. He takes one small dose every 1-7 days. It seems that he still has some brain fog and weight gain.
  16. Michael Harrop

    Causation Memory loss is fuelled by gut microbes in ageing mice (Mar 2026) Intestinal interoceptive dysfunction drives age-associated cognitive decline

    https://www.nature.com/articles/d41586-026-00768-6 https://www.nature.com/articles/s41586-026-10191-6
  17. Michael Harrop

    Antibiotics A single course of antibiotics can leave a lasting mark on the gut microbiome (Mar 2026) Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals

    https://www.scientificamerican.com/article/a-single-course-of-antibiotics-may-reshape-the-gut-microbiome-for-years/ https://www.nature.com/articles/s41591-026-04284-y
  18. Michael Harrop

    Causation Specific gut bacteria species linked to muscle strength (Mar 2026) Roseburia inulinivorans increases muscle strength

    https://medicalxpress.com/news/2026-03-specific-gut-bacteria-species-linked.html https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336980
  19. Michael Harrop

    FMT Why some gut microbes persist after fecal transplants (Feb 2026) Temporal dynamics of gut biosynthetic gene clusters link persistent colonization and engraftment in fecal microbiota transplantation

    https://medicalxpress.com/news/2026-03-stay-stray-gut-microbes-persist.html https://www.tandfonline.com/doi/full/10.1080/19490976.2026.2634469
  20. Michael Harrop

    Phages A virus hiding inside bacteria may help explain colorectal cancer (Feb 2026, n=877) Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis

    https://theconversation.com/a-virus-hiding-inside-bacteria-may-help-explain-colorectal-cancer-276695 https://www.nature.com/articles/s43856-026-01403-1
  21. Michael Harrop

    Other Sleep disruption damages gut's self-repair ability via stress signals from brain (Feb 2026) Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

    https://news.uci.edu/2026/02/05/sleep-disruption-damages-guts-self-repair-ability-via-stress-signals-from-brain/ https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(26)00025-1
  22. Michael Harrop

    Other Hidden biological signals in the gut point to Alzheimer’s as a whole-body disorder (Jan 2026) Gut proteome and microbiome alterations: Analysis of transverse colon samples from pathologically confirmed Alzheimer's disease patients

    https://news.asu.edu/20260116-science-and-technology-roots-alzheimers-disease-extend-beyond-brain https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.71021Abstract
  23. Michael Harrop

    Testing Gut health index measures microbial interactions to track disease (Feb 2026) Imbalance in gut microbial interactions as a marker of health and disease

    https://medicalxpress.com/news/2026-02-gut-health-index-microbial-interactions.html https://www.eurekalert.org/news-releases/1117082 https://www.npr.org/2026/02/27/nx-s1-5724876/scientists-find-a-new-clue-to-help-them-identify-a-healthy-gut-microbiome...
  24. Michael Harrop

    Antibiotics Antibiotic-induced gut microbiome remodeling reduces neuroinflammation in traumatic brain injury (Feb 2026, mice)

    https://neurosciencenews.com/microbiome-tbi-brain-neuroinflammation-30201/ https://www.eurekalert.org/news-releases/1117939 https://www.nature.com/articles/s42003-026-09737-1
  25. Michael Harrop

    Testing Same Poop, Different Results: At-Home Gut Health Tests Are Wildly Inconsistent (Feb 2026) Evaluating the analytical performance of direct-to-consumer gut microbiome testing services

    https://gizmodo.com/same-poop-different-results-at-home-gut-health-tests-are-wildly-inconsistent-study-finds-2000726793 https://www.scientificamerican.com/article/at-home-microbiome-tests-reveal-dramatically-different-results/...
  26. Michael Harrop

    Genetics New Study Links Gut Makeup to Celiac Disease Pathogenesis (Feb 2026, n=12,652) The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition

    https://www.medcentral.com/gastroenterology/new-study-links-gut-makeup-to-celiac-disease-pathogenesis https://www.nature.com/articles/s41588-026-02502-4
  27. Michael Harrop

    Discussion How should we handle preprints?

    I think it's a bad idea to post preprints for the following reasons: There is more coverage and discussion when they're published. So it's better to just wait till then. They sometimes change the title when it's published, and searching titles is generally how we find previous...
  28. Michael Harrop

    Article Three Olympic Athletes Were Just Disqualified for a Novel Reason: PFAS. Their skis and snowboards tested positive for “forever chemicals,” slippery-but-dangerous chemicals now banned in the Games. (Feb 2026)

    https://www.nytimes.com/2026/02/15/climate/olympics-ski-snowboard-wax-pfas-forever-chemicals.html That's very surprising, but nice to see the Olympics is trying to eliminate PFAS.
  29. Michael Harrop

    Study Health Advice From A.I. Chatbots Is Frequently Wrong. In part due to how users are asking their questions (Feb 2026, n=1,298) Reliability of LLMs as medical assistants for the general public: a randomized preregistered study

    https://www.nytimes.com/2026/02/09/well/chatgpt-health-advice.html https://www.nature.com/articles/s41591-025-04074-y
  30. Michael Harrop

    Testing A group of unculturable bacteria (CAG-170) have been found in higher numbers in the gut microbiomes of healthy people (Feb 2026) Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a candidate signature of health

    https://medicalxpress.com/news/2026-02-overlooked-group-gut-bacteria-key.html https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(26)00038-7
  31. Michael Harrop

    Study Microplastic pollution induces algae blooms in experimental ponds but bioplastics are less harmful (Jan 2026)

    https://today.ucsd.edu/story/plastic-pollution-promotes-hazardous-water-conditions-new-study-finds https://www.nature.com/articles/s44458-025-00014-6
  32. Michael Harrop

    Study More than one-third of cancer cases are preventable, massive study finds (Feb 2026) Global and regional cancer burden attributable to modifiable risk factors to inform prevention

    https://www.nature.com/articles/d41586-026-00333-1 https://www.nature.com/articles/s41591-026-04219-7 By "infections", they're referring to HPV https://www.nature.com/articles/d41586-026-00128-4
  33. Michael Harrop

    Other Gut Bacteria Can Inject Proteins Into Human Cells (Jan 2026) Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation

    https://scitechdaily.com/scientists-discover-gut-bacteria-can-inject-proteins-into-human-cells/ https://www.nature.com/articles/s41564-025-02241-y
  34. Michael Harrop

    Article A crisis emerges across the US as ‘forever chemicals’ quietly contaminate drinking water wells (Feb 2026, PFAS)

    https://apnews.com/article/pfas-wells-contamination-forever-chemicals-water-b132294aca85d569926dbf47c0d02355
  35. Michael Harrop

    Other Scientists discover protein that could heal leaky gut and ease depression (Sep 2025, rats) An Intravenous Injection of Reelin Rescues Endogenous Reelin Expression and Epithelial Cell Apoptosis in the Small Intestine Following Chronic Stress

    https://www.sciencedaily.com/releases/2026/02/260201231240.htm https://journals.sagepub.com/doi/10.1177/24705470251381456
  36. Michael Harrop

    Article RFK Jr. Was Raw Milk’s Biggest Fan. Now He Won’t Return Industry Calls. Mark McAfee owns America’s largest raw milk dairy. He thought he’d be advising the Trump administration. What happened? (Jan 2026)

    https://www.motherjones.com/politics/2026/01/rfk-jr-raw-milk/
  37. Michael Harrop

    FMT Fecal transplant capsules show promising results in clinical trials for multiple types of cancer (Jan 2026, n=20) Fecal microbiota transplantation plus immunotherapy in metastatic renal cell carcinoma: the phase 1 PERFORM trial

    https://medicalxpress.com/news/2026-01-fecal-transplant-capsules-results-clinical.html https://www.nature.com/articles/s41591-025-04183-8 The article also covers this study: Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2...
  38. Michael Harrop

    FMT Evaluation of the efficacy of inactivated fecal transplants against Clostridioides difficile: an in vitro study (Jan 2026) "Inhibition of CD growth was observed exclusively in samples containing live bacteria"

    https://link.springer.com/article/10.1007/s11274-025-04767-z Another study showing live bacteria are required for therapeutic effect.
  39. Michael Harrop

    FMT Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial (Jan 2026, n=40) "results suggest that the elimination of deleterious taxa is required for FMT-mediated therapeutic benefit"

    https://www.nature.com/articles/s41591-025-04186-5
  40. Michael Harrop

    FMT Mechanistic insights into FMT for the treatment of ulcerative colitis: analysis of the STOP-Colitis trial (Jan 2026, n=30) "Colonic FMT was superior to nasogastric delivery - 75% clinical response vs 25%"

    https://academic.oup.com/ecco-jcc/advance-article/doi/10.1093/ecco-jcc/jjag006/8441229 Not much info on the donors, so it seems to be the standard/poor criteria.
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