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  1. Michael Harrop

    FMT The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study (Jun 2025, n=172). Partial remission 55%, complete remission 32% for resistance training group, and 67% partial, 45% complete for FMT+resistance group

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06557-5
  2. Michael Harrop

    FMT Fulminant Clostridioides difficile Infection Following Fecal Microbiota Spores Compared to Fecal Microbiota Transplant (May 2025, n=130) Patients receiving VOUST's fecal microbiota spores live-brpk were more likely to develop severe disease, called fulminant C. diff infection

    https://www.newswise.com/articles/new-treatment-for-c-diff-infection-may-be-less-effective-than-traditional-therapy-study-finds/ https://www.cghjournal.org/article/S1542-3565(25)00420-3/abstract Closed access.
  3. Michael Harrop

    FMT Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results (Jun 2025, n=4) "FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up"

    https://www.sciencedirect.com/science/article/pii/S2255534X25000647
  4. Michael Harrop

    Probiotics Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial (Jun 2025, n=190) "incidence of POCD in the probiotic group was significantly lower than in the control group"

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06584-2
  5. Michael Harrop

    Study Polystyrene nanoplastics disrupt the intestinal microenvironment by altering bacteria-host interactions through extracellular vesicle-delivered microRNAs (Jun 2025, mice)

    https://www.nature.com/articles/s41467-025-59884-y
  6. Michael Harrop

    Causation Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study (Jun 2025)

    https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03789-x
  7. Michael Harrop

    FMT Fecal transplants: Study is a 'wake-up call' for the field as researchers identify unintended consequences. (Jun 2025, mice) Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects

    https://www.dw.com/en/fecal-transplants-study-is-a-wake-up-call-for-the-field/a-72817699 https://www.the-independent.com/news/health/fecal-transplants-consequences-research-us-b2765279.html...
  8. Michael Harrop

    FMT Public knowledge, awareness and perception of gut microbiome and faecal microbiota transplantation in Singapore: a survey study (Jun 2025, n=1831) "33% had heard of the gut microbiome, 92% had consumed probiotics, 85% had not heard of FMT, 72% would consider FMT to treat C. diff"

    https://journals.lww.com/smj/fulltext/9900/public_knowledge,_awareness_and_perception_of_gut.196.aspx
  9. Michael Harrop

    Article Kennedy Says ‘Charlatans’ Are No Reason to Block Unproven Stem Cell Treatments. The U.S. health secretary said people should have access to experimental therapies including unregulated uses of stem cells. But some methods have resulted in blindness, tumors and other injuries. (Jun 2025)

    https://www.nytimes.com/2025/06/05/health/kennedy-stem-cells-experimental-treatments.html
  10. Michael Harrop

    Antibiotics Human antibiotics are polluting Earth's rivers, helping bacteria develop the resistance they need to then kill humans (Apr 2025) Antibiotics in the global river system arising from human consumption

    https://www.earth.com/news/earth-rivers-are-highly-saturated-with-human-antibiotics-helping-bacteria-develop-resistance/ https://academic.oup.com/pnasnexus/article/4/4/pgaf096/8113371
  11. Michael Harrop

    Oral Causal association between oral microbiota and oral cancer: a mendelian randomization study (Jun 2025) "Our findings suggest that Prevotella and Veillonella were causally linked to OC"

    https://www.nature.com/articles/s41598-025-05553-5
  12. Michael Harrop

    FMT Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice (Jun 2025) "human-derived microbiota was less effective in clearing C. difficile compared to a mouse-derived microbiota"

    https://journals.asm.org/doi/10.1128/mbio.01108-25
  13. Michael Harrop

    Article Over the last several decades, the FDA has allowed pharma companies to sell hundreds of drugs to patients without adequate evidence that they work and, in many cases, with clear signs that they pose a risk of serious harm (Jun 2025)

    https://jacobin.com/2025/06/fda-approval-drugs-effectiveness-risk/
  14. Michael Harrop

    FMT Donor composition and fiber promote strain engraftment in a randomized controlled trial of fecal microbiota transplant for ulcerative colitis (Jun 2025, n=27) "the effect depends on the specific donor microbiota and not on patient fiber use"

    https://www.cell.com/med/abstract/S2666-6340(25)00134-5
  15. Michael Harrop

    FMT Donor-derived microbial engraftment and gut microbiota shifts associated with weight loss following fecal microbiota transplantation (Jun 2025, n=23) "52% achieved weight loss of more than 5% from baseline. Average weight loss of 8kg/18lbs"

    https://journals.asm.org/doi/10.1128/aem.00120-25 Chinese study. 52% achieved weight loss of more than 5% from baseline. Average weight loss of 8kg (18 lbs). Nonresponders lost 3kg. Contrary to some other studies, they found engraftment to correlate with success. Donors: But they couldn't...
  16. Michael Harrop

    Video PFAS: How This Corporation Secretly Poisoned Our Food, Water, and Blood | More Perfect Union, Jun 2025

    The video covers the known harms and history of PFAS, and then covers this Trump administration's regulatory capture that will prevent anything from being done. Very depressing. https://www.youtube.com/watch?v=Y0lsLnXX4U8
  17. Michael Harrop

    Fungi Gut fungi in very-low-birthweight infants modulate oxygen-induced lung damage (Jan 2025) The fungal microbiota modulate neonatal oxygen-induced lung injury

    https://www.eurekalert.org/news-releases/1086041 https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02032-x
  18. Michael Harrop

    Origins The human milk microbiome is minimally associated with breastfeeding practices (Jun 2025, n=56)

    https://www.nature.com/articles/s41598-025-03907-7
  19. Michael Harrop

    Study Millions of US children have parents with substance use disorder, and the consequences are staggering (May 2025) US Children Living With a Parent With Substance Use Disorder

    https://theconversation.com/millions-of-us-children-have-parents-with-substance-use-disorder-and-the-consequences-are-staggering-new-research-256979 https://jamanetwork.com/journals/jamapediatrics/article-abstract/2833575
  20. Michael Harrop

    FMT Fecal microbiota transplant is associated with resolution of recurrent urinary tract infection (May 2025) "Of 11 patients who had rUTI in the two years preceding FMT, no patient had rUTI over the 2-year follow-up period after FMT"

    https://www.goldjournal.net/article/S0090-4295(25)00515-1/fulltext
  21. Michael Harrop

    Article Toxic pesticide (glyphosate) levels found in tampons 40 times higher than legal limit for water (May 2025)

    https://www.theguardian.com/environment/2025/may/28/toxic-pesticide-levels-found-in-tampons-40-times-higher-than-legal-limit-for-water https://www.pan-uk.org/period-products/ First heavy metals, now pesticides.
  22. Michael Harrop

    Early development Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment (May 2025, mice) "finding suggests that the host early in life has mechanisms to select microbes appropriate for age"

    https://www.nature.com/articles/s41598-025-03661-w Given that dysbiosis generally increases with age, to me, it sounds more like the mucosa gets worse at resisting problematic microbes as age increases.
  23. Michael Harrop

    Oral Swapping spit with your spouse may spread anxiety and depression (Apr 2025, 536 couples) Oral Microbiota Transmission Partially Mediates Depression and Anxiety in Newlywed Couples

    https://newatlas.com/mental-health/oral-microbiome-spouse-anxiety-and-depression/ https://www.xiahepublishing.com/2472-0712/ERHM-2025-00013
  24. Michael Harrop

    FMT Bidirectional modulation of Alzheimer’s disease via gut microbiota: rescue by fecal transplantation from healthy donors and aggravation by colitis-associated dysbiosis (May 2025) "neuroinflammation occurred independently of gut barrier disruption, implicating circulating microbial metabolites"

    https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1593854/full
  25. Michael Harrop

    Article White House releases RFK Jr.-led report on chronic disease (May 2025) The MAHA Report, Make Our Children Healthy Again Assessment

    https://www.whitehouse.gov/maha/ https://www.hhs.gov/press-room/maha-commission-childhood-chronic-disease-root-causes.html The 70-page report: https://www.whitehouse.gov/wp-content/uploads/2025/05/WH-The-MAHA-Report-Assessment.pdf Articles...
  26. Michael Harrop

    Study Industry study sponsorship and conflicts of interest on the effect of unprocessed red meat on cardiovascular disease risk: a systematic review of clinical trials (May 2025) "Most studies without conflicts of interest suggested an unfavorable effect"

    https://www.sciencedirect.com/science/article/abs/pii/S0002916525001261
  27. Michael Harrop

    FMT Therapeutic efficacy of fecal microbiota transplantation in severe food intolerance: a case report (May 2025, 7-year-old autistic child)

    https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1594022/full They have pictures of the patient's stool as it progresses https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1594022/full#F1. This is the first time I can recall seeing that. I...
  28. Michael Harrop

    FMT Investigating fecal microbiota transplants from individuals with anorexia nervosa in antibiotic-treated mice using a cross-over study design (May 2025) "AN-GM may contribute to altered food intake and appetite regulation, which can be ameliorated with FMT from a non-eating disordered donor"

    https://jeatdisord.biomedcentral.com/articles/10.1186/s40337-025-01276-0
  29. Michael Harrop

    FMT Fecal microbiota transplantation alleviates immunosuppressant-associated diarrhea and recurrent urinary tract infection in kidney transplant recipients: a retrospective analysis (May 2025, n=18)

    https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-025-00705-4
  30. Michael Harrop

    Other Almost all babies who contract HPV perinatally eliminate it within the first six months of life (May 2025, n=422) Human Papillomavirus Persistence, Recurrence, and Incidence in Early Childhood

    https://nouvelles.umontreal.ca/en/article/2025/05/14/hpv-babies-free-themselves-of-the-virus-naturally/ https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiaf213/8129394
  31. Michael Harrop

    Antibiotics Metabolic and immune consequences of antibiotic related microbiome alterations during first-line tuberculosis treatment in Bamako, Mali (May 2025, n=30) "Numerous changes in bacterial taxa abundances and inflammation-linked metabolites did not reverse at Month-15"

    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1561459/full
  32. Michael Harrop

    Article Ziploc hit with class-action lawsuit for allegedly misleading claims that the bags are "suitable" or "safe" to use in the freezer and microwave, despite placing people at elevated risk of exposure to microplastics (May 2025)

    https://www.yahoo.com/news/ziploc-hit-class-action-lawsuit-003500387.html With HumanMicrobes.org, I was having donors use compostable bags due to this concern. The compostable ones break easily though.
  33. Michael Harrop

    Other Potent molecule targets chlamydia bacteria while sparing beneficial microbes (Apr 2025) A multi-strategy antimicrobial discovery approach reveals new ways to treat Chlamydia

    https://phys.org/news/2025-05-potent-molecule-chlamydia-bacteria-beneficial.html https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003123 I look forward to the day when I can have sex with everyone I meet without worrying about STIs.
  34. Michael Harrop

    Study Proximity to Golf Courses and Risk of Parkinson Disease (May 2025) "These findings suggest that pesticides applied to golf courses may play a role in the incidence PD for nearby residents"

    https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2833716
  35. Michael Harrop

    Other Early-Life Exposure to Certain Bacteria May Contribute to the Rising Incidence of Impact Early-Onset Colorectal Cancer (Apr 2025) Geographic and age variations in mutational processes in colorectal cancer

    https://www.infectiousdiseaseadvisor.com/news/early-life-exposure-to-certain-bacteria-may-impact-early-onset-colorectal-cancer-incidence/ https://www.nature.com/articles/s41586-025-09025-8
  36. Michael Harrop

    Article Your gut microbes might encourage criminal behavior. Is “My microbes made me do it” a valid legal defense? (May 2025)

    https://www.technologyreview.com/2025/05/09/1116211/gut-microbes-criminal-behavior/ I certainly agree. Which is one reason I think society will be quite utopian once we fix our biological defects.
  37. Michael Harrop

    Other Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome (May 2025, mice) "The results suggest that targeting the gut microbiota may offer a strategy for preventing preeclampsia"

    https://www.nature.com/articles/s41467-025-58533-8
  38. Michael Harrop

    Study Biodegradable microplastics in mice gut trigger metabolic reprogramming, shedding light on safety concerns (May 2025) Incorporation of polylactic acid microplastics into the carbon cycle as a carbon source to remodel the endogenous metabolism of the gut

    https://medicalxpress.com/news/2025-05-biodegradable-microplastics-mice-gut-trigger.html https://www.pnas.org/doi/10.1073/pnas.2417104122 More bad news for bioplastics :(
  39. Michael Harrop

    Antibiotics Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors (May 2025)

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1589704/full A really interesting and well-done study of all the different ways antibiotics negatively impact the gut microbiome, beyond basic measurements like diversity and composition. The report also reveals the...
  40. Michael Harrop

    FMT Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis (May 2025, n=96) FMT from humans to mice confirmed the cognitive benefits were microbiota-dependent

    https://gut.bmj.com/content/early/2025/05/07/gutjnl-2025-335353
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