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  1. Michael Harrop

    Genetics New Study Links Gut Makeup to Celiac Disease Pathogenesis (Feb 2026, n=12,652) The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition

    https://www.medcentral.com/gastroenterology/new-study-links-gut-makeup-to-celiac-disease-pathogenesis https://www.nature.com/articles/s41588-026-02502-4
  2. Michael Harrop

    Discussion How should we handle preprints?

    I think it's a bad idea to post preprints for the following reasons: There is more coverage and discussion when they're published. So it's better to just wait till then. They sometimes change the title when it's published, and searching titles is generally how we find previous...
  3. Michael Harrop

    Article Three Olympic Athletes Were Just Disqualified for a Novel Reason: PFAS. Their skis and snowboards tested positive for “forever chemicals,” slippery-but-dangerous chemicals now banned in the Games. (Feb 2026)

    https://www.nytimes.com/2026/02/15/climate/olympics-ski-snowboard-wax-pfas-forever-chemicals.html That's very surprising, but nice to see the Olympics is trying to eliminate PFAS.
  4. Michael Harrop

    Study Health Advice From A.I. Chatbots Is Frequently Wrong. In part due to how users are asking their questions (Feb 2026, n=1,298) Reliability of LLMs as medical assistants for the general public: a randomized preregistered study

    https://www.nytimes.com/2026/02/09/well/chatgpt-health-advice.html https://www.nature.com/articles/s41591-025-04074-y
  5. Michael Harrop

    Other A group of unculturable bacteria (CAG-170) have been found in higher numbers in the gut microbiomes of healthy people (Feb 2026) Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a candidate signature of health

    https://medicalxpress.com/news/2026-02-overlooked-group-gut-bacteria-key.html https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(26)00038-7
  6. Michael Harrop

    Study Microplastic pollution induces algae blooms in experimental ponds but bioplastics are less harmful (Jan 2026)

    https://today.ucsd.edu/story/plastic-pollution-promotes-hazardous-water-conditions-new-study-finds https://www.nature.com/articles/s44458-025-00014-6
  7. Michael Harrop

    Study More than one-third of cancer cases are preventable, massive study finds (Feb 2026) Global and regional cancer burden attributable to modifiable risk factors to inform prevention

    https://www.nature.com/articles/d41586-026-00333-1 https://www.nature.com/articles/s41591-026-04219-7 By "infections", they're referring to HPV https://www.nature.com/articles/d41586-026-00128-4
  8. Michael Harrop

    Other Gut Bacteria Can Inject Proteins Into Human Cells (Jan 2026) Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation

    https://scitechdaily.com/scientists-discover-gut-bacteria-can-inject-proteins-into-human-cells/ https://www.nature.com/articles/s41564-025-02241-y
  9. Michael Harrop

    Article A crisis emerges across the US as ‘forever chemicals’ quietly contaminate drinking water wells (Feb 2026, PFAS)

    https://apnews.com/article/pfas-wells-contamination-forever-chemicals-water-b132294aca85d569926dbf47c0d02355
  10. Michael Harrop

    Other Scientists discover protein that could heal leaky gut and ease depression (Sep 2025, rats) An Intravenous Injection of Reelin Rescues Endogenous Reelin Expression and Epithelial Cell Apoptosis in the Small Intestine Following Chronic Stress

    https://www.sciencedaily.com/releases/2026/02/260201231240.htm https://journals.sagepub.com/doi/10.1177/24705470251381456
  11. Michael Harrop

    Article RFK Jr. Was Raw Milk’s Biggest Fan. Now He Won’t Return Industry Calls. Mark McAfee owns America’s largest raw milk dairy. He thought he’d be advising the Trump administration. What happened? (Jan 2026)

    https://www.motherjones.com/politics/2026/01/rfk-jr-raw-milk/
  12. Michael Harrop

    FMT Fecal transplant capsules show promising results in clinical trials for multiple types of cancer (Jan 2026, n=20) Fecal microbiota transplantation plus immunotherapy in metastatic renal cell carcinoma: the phase 1 PERFORM trial

    https://medicalxpress.com/news/2026-01-fecal-transplant-capsules-results-clinical.html https://www.nature.com/articles/s41591-025-04183-8 The article also covers this study: Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2...
  13. Michael Harrop

    FMT Evaluation of the efficacy of inactivated fecal transplants against Clostridioides difficile: an in vitro study (Jan 2026) "Inhibition of CD growth was observed exclusively in samples containing live bacteria"

    https://link.springer.com/article/10.1007/s11274-025-04767-z Another study showing live bacteria are required for therapeutic effect.
  14. Michael Harrop

    FMT Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial (Jan 2026, n=40) "results suggest that the elimination of deleterious taxa is required for FMT-mediated therapeutic benefit"

    https://www.nature.com/articles/s41591-025-04186-5
  15. Michael Harrop

    FMT Mechanistic insights into FMT for the treatment of ulcerative colitis: analysis of the STOP-Colitis trial (Jan 2026, n=30) "Colonic FMT was superior to nasogastric delivery - 75% clinical response vs 25%"

    https://academic.oup.com/ecco-jcc/advance-article/doi/10.1093/ecco-jcc/jjag006/8441229 Not much info on the donors, so it seems to be the standard/poor criteria.
  16. Michael Harrop

    Article A leading EU chemical safety institute ousted the director of its cancer research center after the director led a testing program into the safety of the pesticide glyphosate, sparking concerns about chemical industry influence into what has been an independent research institution (Jan 2026)

    https://www.thenewlede.org/2026/01/outrage-at-ramazinni-glyphosate/
  17. Michael Harrop

    FMT Replacing microbiota makes aging intestines young again (Jan 2026) Microbiota from young mice restore the function of aged ISCs

    https://www.eurekalert.org/news-releases/1113710 https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(25)00392-3
  18. Michael Harrop

    Review Environmental pollutants and the gut microbiota: mechanistic links from exposure to systemic disease (Jan 2026) "Increasing evidence reveals that the gut microbiota serves as a central mediator of pollutant-induced physiological dysfunctions"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2026.1737229/full
  19. Michael Harrop

    Oral Microbes living in our mouths could hold the key to obesity prevention (Jan 2026, n=628) Integrative multi-omics analysis reveals oral microbiome-metabolome signatures of obesity

    https://medicalxpress.com/news/2026-01-microbes-mouths-key-obesity.html https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01591-8 This appears to be correlation only. So it doesn't conflict with prior evidence indicating the gut microbiome is the crux that influences the oral microbiome...
  20. Michael Harrop

    Other Exhaled Breath Carries Disease-associated Bacteria from Gut (Jan 2026, n=41) The gut microbiota shapes the human and murine breath volatilome

    https://respiratory-therapy.com/disorders-diseases/infectious-diseases/other-infections/exhaled-breath-carries-disease-associated-bacteria-from-gut/ https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00544-3
  21. Michael Harrop

    Study Tiny RNA molecules in sperm have big impact on baby health. Findings provide strong evidence for epigenetic inheritance of paternal environmental effects (Oct 2025) Epididymal dynamics and preimplantation roles of a sperm-enriched 5′ fragment of tRNA-valine

    https://news.ucsc.edu/2026/01/tiny-rna-epigenetic-inheritance/ https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01137-4
  22. Michael Harrop

    FMT Washed microbiota transplantation relieves atopic dermatitis via gut–skin microbiome rebalancing (Jan 2026, n=23)

    https://www.hmpgloballearningnetwork.com/site/thederm/news/washed-microbiota-transplantation-improves-disease-severity-and-microbial https://link.springer.com/article/10.1186/s12866-026-04717-1
  23. Michael Harrop

    Antibiotics The aggressive use of antibiotics could fuel mood disorders and anxiety (Dec 2025, n=175) Consistent decline of acetylcholine in microbiota-gut-brain axis mediates antibiotic-induced anxiety via regulating hippocampus microglial activation

    https://medicalxpress.com/news/2026-01-aggressive-antibiotics-fuel-mood-disorders.html https://www.nature.com/articles/s41380-025-03431-0
  24. Michael Harrop

    Early development The maternal microbiome influence on pregnancy success: breeding comparison of germ-free and conventionalized mice (Jan 2026) "We observed unexpectedly high maternal and offspring mortality in GF animals. Maternal microbiota might influence offspring health far earlier than previously recognized"

    https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2609405
  25. Michael Harrop

    Article A bombshell’: doubt cast on discovery of microplastics throughout human body (Jan 2026) Some scientists say many detections are most likely error, with one high-profile study called a ‘joke’

    https://www.theguardian.com/environment/2026/jan/13/microplastics-human-body-doubt
  26. Michael Harrop

    FMT A man with auto-brewery syndrome gets relief from faecal transplant (Jan 2026, n=22) Gut microbial ethanol metabolism contributes to auto-brewery syndrome in an observational cohort

    https://www.newscientist.com/article/2510789-man-whose-gut-made-its-own-alcohol-gets-relief-from-faecal-transplant/ https://www.nature.com/articles/s41564-025-02225-y
  27. Michael Harrop

    Other The secret to human intelligence? It might be in our gut. Your gut microbes may have helped build the human brain—and could still be shaping how it works today (Jan 2026) Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment

    https://www.sciencedaily.com/releases/2026/01/260105165806.htm https://scitechdaily.com/your-gut-microbes-may-be-quietly-transforming-how-your-brain-works/ https://www.pnas.org/doi/10.1073/pnas.2426232122
  28. Michael Harrop

    Other Vaginal and gut microbiome dysbiosis linked to endometriosis (Dec 2025, n=22) Comprehensive Analysis of Vaginal and Gut Microbiome Alterations in Endometriosis Patients

    https://www.contemporaryobgyn.net/view/vaginal-and-gut-microbiome-dysbiosis-linked-to-endometriosis https://www.dovepress.com/comprehensive-analysis-of-vaginal-and-gut-microbiome-alterations-in-en-peer-reviewed-fulltext-article-IJWH I've contacted lots of women with endometriosis about this...
  29. Michael Harrop

    Causation A molecule produced by gut bacteria can trigger atherosclerosis (Jul 2025, n=400) Imidazole propionate is a driver and therapeutic target in atherosclerosis

    https://www.gutmicrobiotaforhealth.com/scientists-discover-that-a-gut-microbiota-molecule-causes-atherosclerosis/ https://www.nature.com/articles/s41586-025-09263-w
  30. Michael Harrop

    Other Pesticides and other common chemical pollutants are toxic to our ‘good’ gut bacteria (Nov 2025) Industrial and agricultural chemicals exhibit antimicrobial activity against human gut bacteria in vitro

    https://www.cam.ac.uk/research/news/pesticides-and-other-common-chemical-pollutants-are-toxic-to-our-good-gut-bacteria https://www.nature.com/articles/s41564-025-02182-6
  31. Michael Harrop

    Article Highly cited paper, backed by Monsanto and used as evidence that the herbicide Roundup is safe, is retracted by journal for serious ethical concerns (Dec 2025) Safety Evaluation and Risk Assessment of the Herbicide Roundup and Its Active Ingredient, Glyphosate, for Humans

    https://www.science.org/content/article/journal-retracts-weed-killer-study-backed-monsanto-citing-serious-ethical-concerns https://www.nytimes.com/2026/01/02/climate/glyphosate-roundup-retracted-study.html https://www.sciencedirect.com/science/article/pii/S0273230099913715
  32. Michael Harrop

    Study Fathers' microplastics exposure tied to their children's metabolic problems (Dec 2025) Paternal microplastic exposure alters sperm small non-coding RNAs and affects offspring metabolic health in mice

    https://medicalxpress.com/news/2025-12-fathers-microplastics-exposure-children-metabolic.html https://academic.oup.com/jes/advance-article/doi/10.1210/jendso/bvaf214/8383852
  33. Michael Harrop

    Diet A common food ingredient may shape a child’s health for life (Jul 2025, mice) Maternal emulsifier consumption alters the offspring early-life microbiota and goblet cell function leading to long-lasting diseases susceptibility. Carboxymethylcellulose and polysorbate-80

    https://www.sciencedaily.com/releases/2025/12/251225080732.htm https://www.nature.com/articles/s41467-025-62397-3
  34. Michael Harrop

    Oral Super donor assessment tool for oral microbiome transplantation (Dec 2025, n=93)

    https://link.springer.com/article/10.1186/s12866-025-04630-z Paywalled.
  35. Michael Harrop

    FMT Awareness and perception of fecal microbiota transplantation in Lebanon: a cross-sectional survey among the general population, healthcare workers, physicians, and patients (Dec 2025, n=725) 31% prior awareness, 60% positive perception. Awareness & perception highest among physicians.

    https://journals.sagepub.com/doi/10.1177/17562848251399034
  36. Michael Harrop

    FMT Efficacy of oral and rectal administration of human faecal microbiota transplant (FMT) in human microbiota-associated mouse models (Dec 2025)

    https://www.nature.com/articles/s41598-025-32072-0
  37. Michael Harrop

    FMT Recipients' native bacteria determine the outcome of FMT treatment in inflammatory bowel disease (Dec 2025, n=96) "remission rates were 82.4% for CD patients and 84.4% for UC patients"

    https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2600055 Those are unusually high remission rates.
  38. Michael Harrop

    Probiotics The Hype behind Probiotics (Dec 2025) Popular supplements with billions of “good” microbes really help only a few illnesses, research shows

    https://www.scientificamerican.com/article/the-hype-behind-expensive-probiotic-supplements/ Wow, misinformation: I wonder how much that was impacted by this:
  39. Michael Harrop

    FMT Case Report: Fecal microbiota transplantation via capsules ameliorated clinical outcomes in a patient with multiple sclerosis (Nov 2025)

    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1678759/full
  40. Michael Harrop

    Testing We may finally know what a healthy gut microbiome looks like (Dec 2025, n=34,694) Gut micro-organisms associated with health, nutrition and dietary interventions

    https://www.newscientist.com/article/2508109-we-may-finally-know-what-a-healthy-gut-microbiome-looks-like/ https://www.nature.com/articles/s41586-025-09854-7 Ended with a big caveat there.
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