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  1. Michael Harrop

    Testing We may finally know what a healthy gut microbiome looks like (Dec 2025, n=34,694) Gut micro-organisms associated with health, nutrition and dietary interventions

    https://www.newscientist.com/article/2508109-we-may-finally-know-what-a-healthy-gut-microbiome-looks-like/ https://www.nature.com/articles/s41586-025-09854-7 Ended with a big caveat there.
  2. Michael Harrop

    FMT Obesity-induced gut microbiota transplantation promotes the occurrence and development of hepatocellular carcinoma (Dec 2025, mice)

    https://www.tandfonline.com/doi/full/10.1080/20565623.2025.2599729
  3. Michael Harrop

    Study Do microplastics play a role in the pathogenesis of neurodegenerative diseases? Shared pathophysiological pathways for Alzheimer’s and Parkinson’s disease (review, Nov 2025)

    https://www.uts.edu.au/news/2025/12/five-ways-microplastics-may-harm-your-brain https://link.springer.com/article/10.1007/s11010-025-05428-3
  4. Michael Harrop

    Study Alarming surge in memory problems among young adults (Sep 2025, n=4.5 million) Rising Cognitive Disability as a Public Health Concern Among US Adults Trends From the Behavioral Risk Factor Surveillance System, 2013–2023

    https://www.sciencedaily.com/releases/2025/11/251102011158.htm https://www.neurology.org/doi/10.1212/WNL.0000000000214226
  5. Michael Harrop

    Study Hormone-disrupting chemicals from plastics shown to promote a chronic inflammatory skin condition (Nov 2025, n=20) Plastic associated endocrine disruptors reduce Nicastrin protein and potentiate inflammation in hidradenitis suppurativa skin disease

    https://medicalxpress.com/news/2025-12-hormone-disrupting-chemicals-plastics-shown.html https://www.nature.com/articles/s41467-025-65789-7
  6. Michael Harrop

    Article FDA Issues Warning About Imported Cookware That May Leach Lead: August 2025

    https://www.fda.gov/food/alerts-advisories-safety-information/fda-issues-warning-about-imported-cookware-may-leach-lead-august-2025 They have a table listing all the items, where they were sold, and photos of them. It looks like most of them are imported from India.
  7. Michael Harrop

    Article The ‘Worst Test in Medicine’ is Driving America’s High C-Section Rate. Round-the-clock fetal monitoring leads to unnecessary C-sections, but it’s used in nearly every birth because of business and legal concerns (Nov 2025) A Grave Condition, Placenta accreta, Caused by C-Sections Is now on the Rise

    https://www.nytimes.com/2025/11/06/health/electronic-fetal-monitoring-c-sections.html It’s accompanied by this article: A Grave Condition Caused by C-Sections Is on the Rise. Placenta accreta is a life-threatening condition in which the placenta attaches to scar tissue left by a C-section. It...
  8. Michael Harrop

    FMT The challenges and opportunities in the expanding horizons of microbiota transplant therapies (Nov 2025, editorial)

    https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2559032 This is significant because it's written by Dr. Alexander Khoruts, who runs the main/only stool bank in the US. I wrote to him some months ago about his previous supposed objections to the FDA regulating FMT as a drug, and the...
  9. Michael Harrop

    Article FDA Drug Unit Chief Resigns, and Is Sued by Drug Company. The official, Dr. George Tidmarsh, has become embroiled in an ethical dispute and is now the target of a lawsuit over his actions involving certain drugs tied to a business associate. (Nov 2025)

    https://www.nytimes.com/2025/11/02/health/fda-drug-unit-chief.html
  10. Michael Harrop

    Vagina Awareness of the Vaginal Microbiome and Willingness to Undergo Vaginal Microbiota Transplant (Oct 2025, n=210) "More than 50% were willing or very willing"

    https://www.jognn.org/article/S0884-2175(25)00271-0/abstract The percent of "willing" in this study is generally around 60%.
  11. Michael Harrop

    Diet Gluten sensitivity linked to gut–brain interaction, not gluten itself (Oct 2025, review) Non-coeliac gluten sensitivity

    https://medicalxpress.com/news/2025-10-gluten-sensitivity-linked-gutbrain-interaction.html https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01533-8/abstract
  12. Michael Harrop

    FMT The Super-Donor Phenomenon in Fecal Microbiota Transplantation (Jan 2019, review)

    https://www.frontiersin.org/articles/10.3389/fcimb.2019.00002/full An important paper to have submitted here. Unfortunately, the authors of this review didn't bother to attempt to find a super-donor for their FMT trial...
  13. Michael Harrop

    FMT Fecal Transplant From The Rock Causes Mysterious Side Effects in Man (Oct 2025)

    https://the-peel.com/article/1723/ This doesn't seem to be a real story. See their "about" page: https://the-peel.com/about/ Their bluesky says "on the mission to deliver news before it happens".
  14. Michael Harrop

    FMT Scientists develop a way to track donor bacteria after fecal microbiota transplants (Oct 2025) Long-read metagenomics for strain tracking after faecal microbiota transplant

    https://medicalxpress.com/news/2025-10-scientists-track-donor-bacteria-fecal.html https://www.nature.com/articles/s41564-025-02164-8
  15. Michael Harrop

    FMT Shaping the future of probiotics, live biotherapeutic products, and fecal microbiota transplantation: 30 scientific recommendations from the CHINAGUT Conference (Oct 2025)

    https://onlinelibrary.wiley.com/doi/10.1002/imt2.70083 This is incredibly depressing. Not a single mention of donor quality, and they're promoting the failed & inadequate stool bank model.
  16. Michael Harrop

    FVT Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial (Sep 2025, n=138) "supporting the crucial role of live microbes in mediating clinical efficacy"

    https://www.thelancet.com/journals/langas/article/PIIS2468-1253%2825%2900190-6/abstract A previous study indicated that a sterile fecal filtrate was effective for C. diff. https://humanmicrobiome.info/fmt/#sterile-fecal-filtrate This study says otherwise.
  17. Michael Harrop

    Article Protein Powders and Shakes Contain High Levels of Lead. Consumer Reports investigation (Oct 2025)

    https://www.consumerreports.org/lead/protein-powders-and-shakes-contain-high-levels-of-lead-a4206364640/
  18. Michael Harrop

    Video RFK Jr. hosts roundtable on long COVID (Sep 18, 2025)

    https://www.hhs.gov/press-room/hhs-secretary-kennedy-long-covid-roundtables-action.html https://www.youtube.com/watch?v=NzGbNCAzkcI This video makes this administration seem like a big fucking scam. All the big players in this video know about the gut microbiome and FMT, including Senator...
  19. Michael Harrop

    FMT Assessing healthcare workers as potential stool donors for faecal microbiota transplantation: a cross-sectional study of antimicrobial-resistant gut bacteria and enteropathogenic microorganisms (Sep 2025, n=106) "supports the inclusion of HCWs as potential stool donors for FMT"

    https://www.journalofhospitalinfection.com/article/S0195-6701(25)00277-4/abstract Previous guidelines have recommended against using healthcare workers as donors. This study indicates otherwise.
  20. Michael Harrop

    Study Obesity during pregnancy doubles autism risk and increases ADHD risk by up to 57% (Sep 2024, n=3.6m mother-child pairs) Associations between maternal preconception and pregnancy adiposity and neuropsychiatric and behavioral outcomes in the offspring: A systematic review and meta-analysis

    https://www.unisa.edu.au/media-centre/Releases/2024/obesity-in-mums-doubles-the-risk-of-autism-in-babies/ https://www.sciencedirect.com/science/article/pii/S0165178124004347 Relevant due to the recent RFK/Trump announcement blaming Tylenol. Rhonda Patrick alerted me to this.
  21. Michael Harrop

    FMT Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-ENEMA FMT Trial) (Sep 2025, n=45) "Higher clinical response and quality of life in both FMT groups than placebo"

    https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1648944/full Standard/poor donor quality.
  22. Michael Harrop

    Article Trump admin links Tylenol/acetaminophen use in pregnancy to increased risk of autism despite mixed studies (Sep 2025)

    https://apnews.com/article/tylenol-cause-autism-trump-kennedy-0847ee76eedecbd5e9baa6888b567d66 https://www.pbs.org/newshour/politics/trump-administration-suggests-acetaminophen-during-pregnancy-causes-autism-experts-say-a-link-between-the-two-is-unproven This was their "big September...
  23. Michael Harrop

    FMT Repeated faecal microbiota transplantation for individuals with type 1 diabetes and gastroenteropathy (Sep 2025, n=17) "Participant satisfaction was high, with 86% reporting considerable benefits"

    https://link.springer.com/article/10.1007/s00125-025-06544-x
  24. Michael Harrop

    FMT Gut microbiota characteristics and therapeutic effects of fecal microbiota transplantation in children with autism spectrum disorder in central China: a combined cross-sectional and prospective study (Sep 2025, n=25) "significant improvements to core ASD symptoms and GI comorbidities"

    https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1648471/full I don't see how many donors were used. It's good that they age-matched.
  25. Michael Harrop

    Other Non-antibiotic medications leave lasting mark on gut microbiome, even years after use (Sep 2025) A hidden confounder for microbiome studies: medications used years before sample collection

    https://medicalxpress.com/news/2025-09-medications-gut-microbiome-years.html https://journals.asm.org/doi/10.1128/msystems.00541-25
  26. Michael Harrop

    Article Trump admin releases long awaited MAHA roadmap. The new strategy stops short of surprise regulations and leaves pesticides alone (Sep 2025) The Make Our Children Healthy Again Strategy Report

    https://www.whitehouse.gov/maha/ https://www.whitehouse.gov/wp-content/uploads/2025/09/The-MAHA-Strategy-WH.pdf https://www.usda.gov/about-usda/news/press-releases/2025/09/09/maha-commission-unveils-sweeping-strategy-make-our-children-healthy-again...
  27. Michael Harrop

    Causation Gut microbial production of imidazole propionate drives Parkinson’s pathologies (Sep 2025)

    https://www.nature.com/articles/s41467-025-63473-4
  28. Michael Harrop

    FMT Fecal Microbiota Transplantation by Rectal Enema Improves Short-Term Insulin Resistance in Metabolic Syndrome: A Pilot Randomized Controlled Trial (May 2025, n=18)

    https://www.jomes.org/journal/view.html?doi=10.7570/jomes25014
  29. Michael Harrop

    Early development Establishment of the early gut microbiota in vaginally delivered infants: the influence of maternal gut microbiota outweighs vaginal microbiota (Aug 2025, 26 mother-infant pairs)

    https://journals.asm.org/doi/10.1128/spectrum.01775-25
  30. Michael Harrop

    Article Studies deliver new blow to cancer microbiome literature—and offer a way forward. Two analyses of microbial DNA in tumor samples aim to put controversy-riddled field back on track (Sep 2025, Micronoma)

    https://www.science.org/content/article/studies-deliver-new-blow-cancer-microbiome-literature-and-offer-way-forward I'm posting this because Rob Knight is a major figure in the microbiome world. Martin J. Blaser, M.D. was on their scientific advisory board...
  31. Michael Harrop

    FMT Fecal microbiota transplantation improves bile acid malabsorption in patients with inflammatory bowel disease: results of microbiota and metabolites from two cohort studies (Sept 2025)

    https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-04353-y I think n=106, but they're using the word "pairs" confusingly. I don't think they gave the 24 healthy controls FMT. Donors: Doesn't say how many donors were used. Results:
  32. Michael Harrop

    Antibiotics Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes (Aug 2025) "We find that antibiotic preconditioning reduces efficiency for uptake of CMT-specific strains. Antibiotics introduce uncontrolled variance in the resulting microbiome composition"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1632210/full Another piece of evidence opposing antibiotics prior to FMT.
  33. Michael Harrop

    FMT Obese teens given healthy gut bacteria show lasting drop in diabetes risk (Aug 2025, n=55) Long-term health outcomes in adolescents with obesity treated with faecal microbiota transplantation: 4-year follow-up

    https://medicalxpress.com/news/2025-08-obese-teens-healthy-gut-bacteria.html https://www.nature.com/articles/s41467-025-62752-4 New Zealand group. This is a follow-up to their "gut bugs" study...
  34. Michael Harrop

    Causation Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study (Aug 2025) "Our study revealed a significant causal impact of five GM genera, 10 metabolites, two metabolite ratios, and 22 immune cells"

    https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1620449/full
  35. Michael Harrop

    Study Chronic Exposure to Microplastics Induces Blood–Brain Barrier Impairment, Oxidative Stress, and Neuronal Damage in Rats (Jun 2025)

    https://link.springer.com/article/10.1007/s12035-025-05157-0 https://www.psypost.org/chronic-exposure-to-microplastics-impairs-blood-brain-barrier-and-damages-neurons/
  36. Michael Harrop

    FMT Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial (Aug 2025, n=19) "significant reduction in hepatic encephalopathy severity"

    https://www.mdpi.com/2077-0383/14/17/5981 Donors:
  37. Michael Harrop

    FMT Colonoscopic fecal microbiota transplantation for Mild-to-Moderate Parkinson’s Disease: A randomized controlled trial (Aug 2025, n=30) "alleviates motor and non-motor symptoms"

    https://www.sciencedirect.com/science/article/pii/S0889159125003216 Donor:
  38. Michael Harrop

    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    https://jamanetwork.com/journals/jama/fullarticle/2835314 Subsections: Unleashing AI Healthier Food for Children Harnessing Big Data Financial Toxicity Sounds like more useless, distracting BS, and that they have no plans to do anything about FMT.
  39. Michael Harrop

    Study Mount Sinai study supports evidence that prenatal acetaminophen use may be linked to increased risk of autism and ADHD (Aug 2025, review) Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology

    https://www.eurekalert.org/news-releases/1094641 https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0
  40. Michael Harrop

    Study The Lancet Countdown on health and plastics (2025) "Plastics are a grave, growing, and under-recognised danger to human and planetary health"

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01447-3/abstract
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