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  1. G

    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I have really bad mental-health issues. The most important thing about my mental-health situation, I think, is how every single hour (it seems...I'm only being slightly hyperbolic) my consciousness changes to a new state. So there's extraordinary flux going on 24/7/365 in my consciousness. 1...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    What do you make of this paper? I have no doubt that my own circadian systems are messed up. Not sure how to get my circadian systems back on track...this papers seems to point toward the idea that you have to fix your gut-biota composition in order to fix your circadian systems...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Sorry for asking too many questions; I should see if I can get answers on Google before bugging you. This product ( https://www.jamiesonvitamins.com/products/probiotic-regular-strength-5-billion) seemed to help me enormously regarding my psychiatric issues. 1: What do you make of the five...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: What is your time frame in terms of when you think you might make major progress regarding your effort to secure really good samples of human feces? 2: I was just reading about the incredible things that this molecule ( https://en.wikipedia.org/wiki/Tryptamine ) does. Could one actually take...
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    Thoughts on Psyllium Husk (Metamucil) and Stool Quality

    Michael, what would you say regarding psyllium husk? Is it worth taking? I'm sure there must be lots of scientific papers looking into psyllium husk in terms of its benefits...papers that have large randomized samples.
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Sorry for leaving three comments; that was a lot of stuff to respond to. Did you see all the questions? Just checking that you saw them all and responded to what you wanted to address. I'm curious about this: Is it known why "dynamic equilibrium" emerges from dysbiosis? I think of it like...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Regarding the "attacks" that I mentioned, is it possible that I have extreme dysbiosis and that the extreme dysbiosis means that any new food causes a big negative reaction? Sometimes foods that I've eaten many times will cause my gut to go ballistic; maybe it's just the fact that my regular...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: I'm going through a weird situation. I woke up today feeling better than I've basically ever felt in my whole adult life. It seems like I got a "B-Complex" pill (it has all the B vitamins and some other stuff) to absorb properly in my duodenum or whatever. I also did take a vitamin D and an...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: I find it super depressing to think that we've done irreparable and permanent damage to our gut biota. I know I mentioned this before, but aren't hunter-gatherers who've never made contact with modern medicine able to provide samples that can allow us to (at least in principle) undo the...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I'm curious about something. You yourself don't have "dysbiosis", I assume, since you know so much about gut biota and therefore you must have achieved "eubiosis". So if you don't have "dysbiosis", how can it be that your gut biota are harming you enough that you're trying to find an optimal...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    The more I read on the tryptophan pathway, the more I'm like "This is an extremely plausible explanation for what's wrong with me". Did you see the below? One of the best things I've ever read about gut biota. https://journals.physiology.org/doi/full/10.1152/physrev.00018.2018
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Thanks! 1: Did you see my other comment there too? I posted two comments in a row; sorry about that. 2: What do you make of this ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855262/ )? It says: "the relative abundance of Bacteroidetes and Firmicutes, and the proportions of Bifidobacteria...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I experience so much variability in terms of my actual consciousness and in terms of my response to medications. My consciousness is always "in flux", so to speak. And my response to medications is completely chaotic. I think that you and I are (to some degree) in the same boat. I know that you...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    What do you make of the below that I posted? I don't know how much you know about psychiatry and psychiatric medications. But I wonder what you make of the gastrointestinal aspect of what I talk about below. Regarding the gut itself but also gut biota (!!!), do you think that there's a possible...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Would you say that the fecal-transplantation thing is getting more popular and getting more resources behind it? 2: If so, if I wait a couple years then is it likely that (here in Canada) I'll be able to get a fecal-transplantation treatment done more cheaply and also with higher-quality...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Regarding your own situation, what exact condition are you trying to cure? 2: What do you make of this? https://www.mdpi.com/2073-4425/14/7/1506
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I started taking vitamin D. Just 3000 IUs a day. My gut feels a lot better. My sleep is better too. A lot of things are better. It's super weird though because I have no idea how vitamin D is helping me. My brain is doing a LOT better in many ways. Do you know about the below stuff...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: So what should I do regarding my gut dysbiosis or whatever I have? I mean, I can go to a gut specialist but you're saying they might not treat me? Like if my suffering is related to gut biota then I'm screwed, you're saying? Or...? 2: Is this nonsense...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    FYI, I found this: https://www.sciencedirect.com/science/article/abs/pii/S0963996918308731 Kefir is a probiotic and fermented dairy product authentically produced from kefir grains. Kefir grain, as a natural starter culture, contains numerous lactic acid bacteria, acetic acid bacteria and...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Sorry for all the posts; one final quick thing. One thing that is really spooky and disturbing to me is the idea that someone might have psychiatric issues their whole life, not think that they particularly have any gut issues, and be suffering from gut issues despite having no idea that...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Also, I don't get how it can be necessary to find "superstar" fecal material in order to get major results with fecal transplantation. I understand why there might be interest in finding the "best of the best" material, especially if it's possible to study and replicate it. But finding like...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Here's more stuff on iron: https://www.mdpi.com/1422-0067/22/7/3646 The multi-factorial mechanisms by which IBD-associated dysbiosis develops are not fully understood, and it is unclear whether this dysbiosis should be considered a cause or consequence of IBD. Luminal iron likely to...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: I hope to see some specialists regarding my gut. But I don't know what kind of tests they'll be able to do. If you see a gut specialist within the medical system then it's not like they're going to test your gut-biota composition, are they? 2: And I have no idea what they'll prescribe for...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    What do you think about the info in this ( https://www.mdpi.com/2072-6643/14/8/1567 ), including Table 1? Seems like useful info. Regarding the gut/brain axis (and the gut/body axis generally, I guess?), what is the best overall mega-review that just talks about all the different strains of...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Why would you say that having producers (in your gut) produce X is so much better than supplementing X? 2; I just took some magnesium; I was feeling extremely tired and awful but now I feel better. I wonder how many people are Mg-deficient. Take a look at this...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    I still keep coming back to the point that if you have some "super poop" then by analyzing it very closing you can obtain the knowledge of which biota are present and in what proportion. Once you have that knowledge, you can ultimately strive to duplicate that same situation in everyone's gut...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    What are the basic things that are known about what microbiota one wants to have in their gut? For example, what proportion of butyrate-producing biota should one have...is anything known about that? It seems like butyrate is very important...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Sorry to ask a basic question, but is there anywhere where you have like your top 10 favorite papers demonstrating the power of gut biota regarding human health? Like, if I want to really make the case (regarding gut biota and human health) then I would love to see the papers that you've...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: Is there any way to know how "ideal" the average person's gut-biota situation was back when we were hunter-gatherers? Is the expectation that what is "ideal" for the human body and brain was common or even dominant in the past? 2: If you look here (...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Any thoughts on the below, by the way? I urge you to read the paper all the way through. It's so interesting. And it has tons of fantastic sources too. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187765/ In this opinion article we would like to propose alternate views on selective serotonin...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    OK, just one final thing (Sorry: I may have said "final thing" before.) If rich people go to some private lab (I assume there are private labs that will do things for rich people) then what can that lab actually do (for the rich person) gut-biota wise? We have a bunch of literature. And we have...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Incidentally, if you don't mind my asking, how did you arrive at the view that gut-biota stuff was the key to fixing your own health?
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    OK, so is it likely (would you say?) that using "super poop" to upgrade other donors will lead to a situation where there is (ultimately) enough "super poop" for everyone on the planet?
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Thanks! Very final question now (I promise). If you can't "replicate" the "super poop" that you get from the ideal donor, then of what use is the "super poop"? I don't get it. Without replication, the "super poop" won't be able to help very many people, correct?
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Sorry to bring up something random. But I happen to have bipolar disorder and I had this weird situation where my gut like stopped moving. My gut was like ultra-constipated. I took some lithium just now and my gut like roared to life and I felt better within seconds. Within roughly 30 seconds...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Two final quick things. 1: Why think that there's one "ideal" composition? And furthermore, if everyone gets seeded with the ideal "recipe", will there be some downside or vulnerability if there's no diversity in human gut-biota composition? Not sure what the value of diversity is. 2: If you...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    1: I'm curious...would you ideally want to use a donor who's some kind of famous athlete or superstar athlete? Or would material from such a person be no better than getting material from someone who's like a completely unknown professional athlete who doesn't play in any famous sports league or...
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    Suppose that the gut/brain axis is as important (in psychiatry) as the peer-reviewed literature seems to indicate. Why then isn't fecal transplantation an extremely famous and celebrated psychiatric treatment?

    Thanks so much for the excellent response; I appreciate it. Once it's ensured that donors are truly free of issues, do the statistics then show a profound impact? This brings us back to the question that I was asking. If it works, why isn't it taking the psychiatric and medical worlds by...
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