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    Diet Gluten sensitivity linked to gut–brain interaction, not gluten itself (Oct 2025, review) Non-coeliac gluten sensitivity

    Interesting study. Anecdotal but I'm dealing with an issue right now where I tried to introduce more carbs to my diet and am now having some serious gut issues. I was tested for celiac disease about a year ago and was negative. Hope you're doing good Michael and thanks for always posting new...
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    Donors Does stool donor sex and age matter? Are there differences in receiving fecal transplants (FMT) from male vs. female donors? And different age groups and enterotypes? Donor matching

    I don't have a super strong opinion on whether or not it matters if you get FMT from a man or woman, just thought I'd mention that there's anecdotal stuff out there and that if I were looking for a personal donor I'd probably factor it in. In theory, the gut biome does modulate hormones, so its...
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    Donors Does stool donor sex and age matter? Are there differences in receiving fecal transplants (FMT) from male vs. female donors? And different age groups and enterotypes? Donor matching

    Yeah there's a few studies but this (anecdotal) first hand account is interesting. I'd still get a FMT from a woman if she met all other criteria. I just noticed that the author of this post is going by a male name and mentioned he was considering a female donor (no judgement here!) and I...
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    Donors Does stool donor sex and age matter? Are there differences in receiving fecal transplants (FMT) from male vs. female donors? And different age groups and enterotypes? Donor matching

    I'd also add the potential for hormonal disturbance that can happen when transplanting from female to male or male to female. I know there's conflicting research on this but in my own hunt for FMT transplant donors, this is something I would seriously consider as a potential variable of concern.
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    Enhancing fmt reduced to less than 1% as effective as it used to be after i started taking high amounts of inulin daily years ago (reason likely being severely damaging my gut mucus layer)

    I had a roommate once for a year or so who was bipolar and had manic episodes. Obviously this is just anecdotal, but it wasn't until he started working out with me and drinking constant high fiber smoothies did he start to become manic. For some reason it always stuck out to me that when he...
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    Enhancing fmt reduced to less than 1% as effective as it used to be after i started taking high amounts of inulin daily years ago (reason likely being severely damaging my gut mucus layer)

    This is an interesting thread so thought I'd add my experience with inulin. I started taking it as a component of some nut bars I was eating and at first it worked GREAT, my stools totally regulated for a couple weeks, but then they went right back to loose and unpredictable so I stopped. I...
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    Severe Microbiome Dysbiosis – Seeking Feedback and Practitioner/Research Referral

    I've tried akkermansia a few times, and one of those times I got the mixture where they also have Clostridium butyricum (and others), and that one I felt like actually helped pretty quickly. I want to say it was "glucose control." My experience with the akkermansia alone actually seemed at first...
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    Severe Microbiome Dysbiosis – Seeking Feedback and Practitioner/Research Referral

    There's a company that makes akkermansia now if you're looking to supplement that. I drink a TON of kefir, like, a TON, and that's helped me a lot. I believe the company that makes akkermansia also makes a few other SCFA bacteria strains in supplement form. I've had mixed results with them, but...
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    Article Trump admin links Tylenol/acetaminophen use in pregnancy to increased risk of autism despite mixed studies (Sep 2025)

    In Utero Exposure to Caffeine and Acetaminophen, the Gut Microbiome, and Neurodevelopmental Outcomes: A Prospective Birth Cohort Study Pregnant individuals are exposed to acetaminophen and caffeine, but it is unknown how these exposures interact with the developing gut microbiome. We aimed to...
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    Other Non-antibiotic medications leave lasting mark on gut microbiome, even years after use (Sep 2025) A hidden confounder for microbiome studies: medications used years before sample collection

    I've wondered about this for a long time since my rescue meds for epilepsy are heavy benzos and I've noticed my gut seems better the day after I take them. That's not to suggest they're good long term or a real solution, but I suspected maybe they were doing something along these lines. More...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Why does everyone on here hate RFK Jr.? While I'm pissed they haven't addressed FMT yet, I'm glad they're finally bringing a lot of medical corruption into the mainstream for everyone to see. Consider that the vast majority of the US now understands just how corrupt big pharma actually is, and...
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    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    I think we're using different language to approximate the same meaning. They shouldn't be using bad donors and bad samples. Who is the person running the bad bank right now? edit: shouldn't
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    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    As I've mentioned in other comments, if they open them up they have to be regulated, didn't mean to mislead with my comment by leaving that out. Edit: Really looking forward to your FMT videos! I've done some on Rumble about epilepsy and the one I did on why the Amish have higher rates of...
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    Article Priorities for a New FDA | Martin Makary, Vinay Prasad (Jun 2025)

    I think the problem here is that all the possible ways of making this popular or well known are gatekept by institutions that have money invested in big pharma (mutual funds and stuff), and so would suffer financially from cures coming out. Everyone knows how crony capitalism works and then acts...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Again, this isn't relevant to this thread and I don't mean to sound rude, but the shots were ineffective and unsafe. Corporate media, corrupt govt, and big pharma were not trustworthy. That being said, I'm also very upset that nobody in the current administration isn't bringing up FMT at all. It...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    The covid vaccines cause heart damage and have been pulled from the recommended vaccine schedule. (Not all vaccines are bad). We're far past "both sides have valid points" on this specific subject. Edit: please just reread my previous comment about bad faith actors.
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    Study Breakthrough as two FDA-approved drugs (letrozole and irinotecan) are found to reverse Alzheimer’s — including restoring memory (Jul 2025, mice) Cell-type-directed network-correcting combination therapy for Alzheimer’s disease

    https://nypost.com/2025/07/27/health/breakthrough-as-two-fda-approved-drugs-are-found-to-reverse-alzheimers-including-restoring-memory/ https://www.cell.com/cell/fulltext/S0092-8674(25)00737-8 "In what one researcher called a “mock clinical trial,” they then mined 1.4 million patients’ medical...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Let us know a time and a date and I'm in! It's worth trying! As a side note, I would highly recommend avoiding Bill Gates foundation. They lost credibility with their covid vaccine tyranny push. Anyone who isn't liberally biased is going to associate FMT with "experimental dangerous medicine...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    There's a nugget here worth exploring: If we picked a specific day and a specific time, we could maybe tweet at someone like RFK Jr, and ALL OF US (pre-coordinate the time) respond to the pro-FMT post, pumping it up. Tons of viral stuff start that way, a small and specific community giving the...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Thanks for the corrections, I'll do more research! Bummer they're using such bad donors man that's not safe.
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Yeah so what I mean is that the FDA won't allow studies to be done on FMT for off label use, because... they banned FMT for off label use. They're essentially saying you can't do this treatment until more studies are done, and then BLOCKING any more studies from being done. A large amount of the...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    Are they not approving FMT comments in the scienceforum website? Kinda reminds me of reddit if so. I always thought it was hilarious on reddit that one of the top moderators of all time was maxwellhill who stopped posting and moderating the day Ghislane Maxwell got arrested. Never liked...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    True, but it IS their job to ALLOW the studies to be done, which they currently refuse to do. Yeah this variability is what makes having more than case studies good, but what frustrates me beyond sense is that they are gatekeeping any studies being done on this. The FDA in 2024 shut down all...
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    Blog The FDA and FMT regulation, part 2. (Jul 2024, HumanMicrobes.org) I met with the FDA. Here's what I shared with them, and their response.

    I've been accused of the same thing, viewing it as a holy grail, but I think the problem lies with how doctors and scientists view case studies. Before modernist "science," things were VERY different. Here's an example: If a man says "I built this contraption and I can use it to fly!" and you...
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    The power of olive oil -- significant changes to gut microbiome, stool, and food tolerances

    Very interesting. I've tried keto diet twice now (I have epilepsy and 70% of people with epilepsy can be functionally cured by adhering to keto). My second time doing keto was roughly a month ago and for the first week felt AMAZING. Literally all the inflammation in my body went away and I could...
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    Article F.D.A. to Use A.I. in Drug Approvals to ‘Radically Increase Efficiency’. With a Trump-driven reduction of nearly 2,000 employees, agency officials view artificial intelligence as a way to speed drugs to the market. (Jun 2025)

    It will return other studies (animal models) depending on how I phrase the question. But I like your thinking and I'm going to try many variants of questions from now on to see what range of results I get. I do think a lot of models restrict saying anything is a "cure" specifically because of...
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    Has anyone else tried Keto Diet or similar to modify their gut biome?

    Thank you very much for this heads up. I've read about it enough to see many red flags. Also thanks for the SIBO info because I had a suspicion it was one of those "we're making a set of symptoms into a disease to sell medicine" situation. The part I found the most interesting is that you are...
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    Has anyone else tried Keto Diet or similar to modify their gut biome?

    I've tried keto diet twice now to help with my epilepsy with mixed results both times. The first time I didn't eat enough fat and made my gut significantly worse for a couple weeks, and during that period made my epilepsy worse as well. That was roughly two years ago. Since then I had a gut...
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    Article F.D.A. to Use A.I. in Drug Approvals to ‘Radically Increase Efficiency’. With a Trump-driven reduction of nearly 2,000 employees, agency officials view artificial intelligence as a way to speed drugs to the market. (Jun 2025)

    Whoever programs the AI, as well as however the prompting is phrased, will determine the output to a large extent. This could probably get its own entire thread but for the sake of simplicity I think the vaccine misinformation censorship was a really good example of a well-meaning idea going off...
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    Article F.D.A. to Use A.I. in Drug Approvals to ‘Radically Increase Efficiency’. With a Trump-driven reduction of nearly 2,000 employees, agency officials view artificial intelligence as a way to speed drugs to the market. (Jun 2025)

    I'll check this out, sounds interesting. Something I've come across a lot in studying how the gut biome effects the body/chronic illness is IL-6 (interleukin 6). My understanding is that some strains of bacteria stimulate this cytokine in the body which leads to things like IBS, arthritis, and...
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    Article Finch wins US jury trial against Ferring over fecal-transplant patents (Aug 2024, Rebyota)

    I couldn't find any info on the content of either company's "FMT." I forget which company it was but one of them has a "donor" page where you can apply, but they don't go into specifics ANYWHERE which drives me nuts because obviously I think it should all be open source, including the stool...
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    Article F.D.A. to Use A.I. in Drug Approvals to ‘Radically Increase Efficiency’. With a Trump-driven reduction of nearly 2,000 employees, agency officials view artificial intelligence as a way to speed drugs to the market. (Jun 2025)

    F.D.A. to Use A.I. in Drug Approvals to ‘Radically Increase Efficiency’ With a Trump-driven reduction of nearly 2,000 employees, agency officials view artificial intelligence as a way to speed drugs to the market...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Good post and yes I know about the pitfalls of a mentality where antibiotics become the go-to treatment. It's interesting you mention the mucosa since the main strain I've been trying to fight off is Klebsiella P. It can survive off just the mucosa which is why for 70% of people with epilepsy...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Those who allowed regulatory capture of the FDA are guilty and should be prosecuted. The companies that captured the FDA should be prosecuted as well. The future is bright and we will have cures. Everyone standing in the way will be exposed. Have some optimism! Optimism obviously doesn't mean...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    I suspect the MOMENT they start talking about gut bacteria (FOR REAL, and not just "eat healthy for your gut bugs", they start talking about Klebsiella causing Epilepsy, Desulfovibrio causing Parkinsons, big pharma stocks are absolutely going to tank and go to ZERO, maybe even criminal referrals...
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    FMT Preliminary Results From a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients With Mild-to-Moderate Crohn's Disease (Jun 2025, n=34) Terminated early due to futility.

    Isn't Canada the country that suggests medical assisted suicide to people with mental health problems?
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    FMT Preliminary Results From a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients With Mild-to-Moderate Crohn's Disease (Jun 2025, n=34) Terminated early due to futility.

    Huh, do we know who funded the study?
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    Discussion Feel free to provide feedback for a new logo

    This is pretty cool, I think I like the light head with the blue body.
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Haha NICE! Dude this is recent, which means maybe it'll take a few days to get some responses. Unless I'm misunderstanding the timing since these seem to be archived. You can always frame this as a strategic weakness of the US military/civil defense: if China drops Klebsiella p into our water...
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    Healthcare system Incoming trump admin with RFK signals new start for FDA

    Has anyone considered selling this to the military as a way to reduce PTSD, tinnitus, vertigo? There's studies showing it works for those things, and the military might have an interest. Anything domestic runs up against big pharma, buuuut there's always exceptions. The tinnitus thing is...
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