FMT and COVID-19, vaccines. Any concerns about COVID vaccination affecting FMT quality? Does it matter if the donor is vaccinated?

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Hoping4AFix

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Have read through the wiki and the forum and this hasn't been touched on, although I'm sure you would have touched on it somewhere on Reddit (can't find anything through Google).
 
FMT donor quality?

There is general info about vaccines here https://humanmicrobiome.info/immune-system.

I don't recall any good evidence that COVID vaccines would be an issue for FMT donors. Someone shared some links via email but they were poor quality. I think one was a retracted paper from S. Hazan about bifido being reduced.
 
Michael Harrop said:
FMT donor quality?

There is general info about vaccines here https://humanmicrobiome.info/immune-system.

I don't recall any good evidence that COVID vaccines would be an issue for FMT donors. Someone shared some links via email but they were poor quality. I think one was a retracted paper from S. Hazan about bifido being reduced.
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Thanks, I had skipped that page - had no idea there was vaccine stuff on it!

Reviewing what I'd seen previously, it appears that the covid vaccine and infection of the virus itself both have the potential to affect the gut, so not isolated to the vaccine.

I developed some kind of IBD condition a week after having a Moderna shot, so had it in my head that it likely had some impact on the microbiome, but probably a different mechanism.

Disregard I guess.

Thanks.
 
Hoping4AFix said:
so had it in my head that it likely had some impact on the microbiome, but probably a different mechanism
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As you said, both vaccines and the viruses they're made to protect against have the ability to impact the gut microbiome.
 
I have a question if the donor was vaccinated for Covid is it gonna transfer in their poop . If I ingest the poop will I get the vaccine too?
 
Firstly, keep in mind that there's no live virus in the vaccine, depending on the vaccine it's either a protein from the virus or a RNA molecule encoding a protein of the virus, neither of which can replicate in the human body. So the most there ever will exist is in that person's arm immediately after the shot, then it slowly gets cleared from the body over time.

So while it's theoretically possible (though unlikely) that a few of those molecules make it through the bloodstream of the vaccine recipient and into his or her digestive secretions, bile, etc. and get excreted in the feces, the concentration will be FAR lower than it is in the injection site in the person's arm. Our mucous membranes are exposed to foreign proteins from all sorts of organisms all the time, having a few coronavirus proteins touch them is not any different (and if you've been on Earth since 2020, you likely have had single particles of this virus somewhere on your body at some time).

I wouldn't worry about it too much even if the person was vaccinated yesterday--and if the vaccination was months ago then it's as if it never happened. I mean for the purposes of "second hand vaccination" like you seem to be implying--a vaccinated person is less likely to have gotten sick with COVID recently, and being sick with COVID may well have an impact on the microbiome, so in THAT sense it could possibly make a real difference, indirectly.
 
The issue shouldn't be whether or not you'd get a second-hand vaccination, but whether or not the vaccine activated the immune system in such a way as to negatively impact the gut microbiome.
 
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