On the one hand, HMO's have good evidence:
https://www.mdpi.com/2227-9067/8/9/804
However, Akkermansia as a probiotic, isn't well studied AFAIK. A high gut population may be good, but it doesn't necessarily follow that we can directly put Akkermansia into the gut via a probiotic and get...
Although it doesn't seem to work right now (1), maybe it's worth trying to make a backup if it's cheap.
I'd like to see the collection procedure and how to minimise oxygen exposure. I'd expect it to be better to freeze it at home ASAP than benefit from freezing at a lower temperature with more...
I really don't have enough experience with probiotics, other than to say that I found food and protocol to be far more useful. This is just my experience. But that was a while ago.
Building and improving has been a slow process taking months of trial and error, but consistently doing the things...
This search term led me to some interesting studies. I'd recommend a Google Scholar alert on it and using PDF AI questioning to speed up reading them. It led me to these:
Apparently mucin digestion is a more recent adaptation <~1000 year old. But this is only from 8 samples in the Mexico area...
I wouldn't be so quick to jump to thinking about FMT. Isn't it really hard to find a donar healthy enough to bring risk low enough?
If you have access to a good donar, then maybe skip what I'm about to write, because the following won't bring back extinct microbiota.
What work have you done...