Recent content by indigo34

Aren't women in pain (which is partially mediated by the microbiome) more likely to take pain relievers? So couldn't the real association be, women who experience more pain are more likely to take Tylenol during pregnancy and it's more the desire for pain relief demonstrating the effect than the...

Can you provide a source on this? I've heard they are looking into other types of AI but my understanding was that the best and closest to AGI were all LLMs. I have not done much research in this area though. I've heard that the so-called "alignment problem" - AI being aligned to human...

It seems like you're conflating a lot of different things with this statement or perhaps I am misunderstanding you. It seems like you are calling me naive and a MAGA supporter. Is that correct? I'm definitely not part of "MAGA." I am located in the U.S. but I've never voted for Trump. My...

I've changed my opinion of Makary after hearing more of his interviews and reading more articles about what he's doing. He seems pro big-pharma when initally he was claiming to be skeptical.

Would it be worth trying to contact Finch? About improving the quality of their donors and getting their product approved for other conditions (i.e. IBS) From their website it seems like they are trying to patent FMT for C. diff, autism, IBD, Parkinson's, etc, and they have 70 patents related...

It's interesting that there was a trend toward reduced daily off time during the "induction phase" of about 1 FMT per week that disappeared when they switched to the "maintenance phase" of 1 FMT per month.

I've been on a ketogenic diet for a little over a year. That's because carbs tend to give me extreme bloating and discomfort. Fiber makes things worse for me too (causes loose stool and urgency) especially soluble fiber. Keto hasn't magically cured me but I feel less bad eating that way...

This is scary. AI sometimes hallucinates citations that don't exist, which apparently happened in the recent MAHA report. I wonder if that's happened in other recent peer-reviewed studies. We know AI lies often too, so I don't see why they think it would be safe to use in scientific studies -...

Is this actually true? At least for Alzheimer's I thought that the research demonstrating there is a causal relationship was falsified, and that the drugs they developed based on this theory, which target beta-amyloid plaques, do not help Alzheimer's patients...

Too bad it's not open access. Results seem way overstated. They didn't use normal mice but antibiotic-treated mice. That likely dramatically affected their results and therefore makes them less translatable to situations where FMTs are given without antibiotic pre-treatment. Interesting they...

The references mention analyzing fetal tissue samples so I assume the article followed the same methodology. They don't specify how they obtained the samples in most cases but I suspect it was through abortion procedures. https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30737-3...

I wonder if someone read the letter I gave to Senator Cassidy or if they were already aware of the connection. I never heard anything back of course though. He mentions it again around 12 minutes in. If they (HHS) come out and say there is a connection between autism and the microbiome I feel...

I suppose you haven't read this: Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT (2018) https://www.cell.com/cell/fulltext/S0092-8674(18)31108-5?

Relevant text of the article: It seems like the microbiome could fit into RFK's framework of ideas, if he is willing to make some modifications. He is right that too much focus was taken off fortifying the immune system, which the microbiome heavily influences, and instead on manufacturing...

I heard Martin Makary say in an interview that he believes microbiome disruption to be the most likely cause of autism, so hopefully he already relayed that information to RFK. I'm hoping for the same with respect to his influence.