Microbiome studies, news, media
News and info related to the human microbiome. With an evidence-based focus. Studies, articles, videos, podcasts, etc.
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Aging (8)
Antibiotics (36)
Archaea (1)
Causation (27)
Diet (7)
Early development (17)
FMT (164)
Fungi (5)
FVT (5)
Genetics (5)
Mucosa (1)
Oral (10)
Origins (2)
Parasites (2)
Phages (8)
Prebiotics (3)
Probiotics (18)
Review (8)
Sex differences (1)
Sexual behavior (2)
Small intestine/upper GI (3)
Testing (7)
Vaccines (5)
Vagina (5)
Virome (1)
Weight (3)
Other (74)
Article (17)
Video (8)
Blog (13)
Podcast (1)
FMT
Scientists develop a way to track donor bacteria after fecal microbiota transplants (Oct 2025) Long-read metagenomics for strain tracking after faecal microbiota transplant
- Michael Harrop
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- Michael Harrop
FMT
Shaping the future of probiotics, live biotherapeutic products, and fecal microbiota transplantation: 30 scientific recommendations from the CHINAGUT Conference (Oct 2025)
- Michael Harrop
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- Michael Harrop
FVT
Effects of lyophilised faecal filtrate compared with lyophilised donor stool on Clostridioides difficile recurrence: a multicentre, randomised, double-blinded, non-inferiority trial (Sep 2025, n=138) "supporting the crucial role of live microbes in mediating clinical efficacy"
- Michael Harrop
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- Michael Harrop
FMT
Assessing healthcare workers as potential stool donors for faecal microbiota transplantation: a cross-sectional study of antimicrobial-resistant gut bacteria and enteropathogenic microorganisms (Sep 2025, n=106) "supports the inclusion of HCWs as potential stool donors for FMT"
- Michael Harrop
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- Michael Harrop
FMT
Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-ENEMA FMT Trial) (Sep 2025, n=45) "Higher clinical response and quality of life in both FMT groups than placebo"
- Michael Harrop
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- Michael Harrop
FMT
Gut microbiota characteristics and therapeutic effects of fecal microbiota transplantation in children with autism spectrum disorder in central China: a combined cross-sectional and prospective study (Sep 2025, n=25) "significant improvements to core ASD symptoms and GI comorbidities"
- Michael Harrop
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- Michael Harrop
Causation
Gut microbial production of imidazole propionate drives Parkinson’s pathologies (Sep 2025)
- Michael Harrop
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- Michael Harrop
FMT
Fecal Microbiota Transplantation by Rectal Enema Improves Short-Term Insulin Resistance in Metabolic Syndrome: A Pilot Randomized Controlled Trial (May 2025, n=18)
- Michael Harrop
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- Michael Harrop
Early development
Establishment of the early gut microbiota in vaginally delivered infants: the influence of maternal gut microbiota outweighs vaginal microbiota (Aug 2025, 26 mother-infant pairs)
- Michael Harrop
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- Michael Harrop
Antibiotics
Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes (Aug 2025) "We find that antibiotic preconditioning reduces efficiency for uptake of CMT-specific strains. Antibiotics introduce uncontrolled variance in the resulting microbiome composition"
- Michael Harrop
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- Michael Harrop
FMT
Obese teens given healthy gut bacteria show lasting drop in diabetes risk (Aug 2025, n=55) Long-term health outcomes in adolescents with obesity treated with faecal microbiota transplantation: 4-year follow-up
- Michael Harrop
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- Michael Harrop
FMT
Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial (Aug 2025, n=20)
- Michael Harrop
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- Michael Harrop
Causation
Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study (Aug 2025) "Our study revealed a significant causal impact of five GM genera, 10 metabolites, two metabolite ratios, and 22 immune cells"
- Michael Harrop
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- Michael Harrop
FMT
Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial (Aug 2025, n=19) "significant reduction in hepatic encephalopathy severity"
- Michael Harrop
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- Michael Harrop
FMT
Colonoscopic fecal microbiota transplantation for Mild-to-Moderate Parkinson’s Disease: A randomized controlled trial (Aug 2025, n=30) "alleviates motor and non-motor symptoms"
- Michael Harrop
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- Michael Harrop
FMT
Consecutive fecal microbiota transplantation for metabolic dysfunction-associated steatotic liver disease: a randomized controlled trial (Aug 2025, n=20) "FMT did not significantly affect hepatic steatosis, glucose tolerance, liver biochemistry, or gut microbiota signatures"
- Michael Harrop
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- Michael Harrop
Causation
Newly discovered gut bacteria proteins influence hormones, metabolism and bone density (Jul 2025, mice) Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism
- Michael Harrop
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- Michael Harrop
- Michael Harrop
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- SFBayFMT5
Aging
Identification of gut microbiota causally associated with aging and longevity and mediation roles of the cerebrospinal fluid proteins: proteomic genetic evidence from Mendelian randomization (Jul 2025)
- Michael Harrop
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- Michael Harrop
Other
Previously undetectable biomarkers in gut microbiome may predict 'invisible' chronic fatigue syndrome, long COVID (Jul 2025, n=249) AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome
- Michael Harrop
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- Michael Harrop
Other
Microbiome disruption by common drugs raises new safety concerns. Nearly 1/3 of the tested non-antibiotic drugs disrupt gut microbiota, weakening natural defenses and promoting harmful bacteria like Salmonella (Jul 2025, mice) Non-antibiotics disrupt colonization resistance against enteropathogens
- Michael Harrop
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- NameHere
Antibiotics
Influence of perinatal antibiotic on neonatal gut microbiota: a prospective cohort study (Jul 2025, n=182) "perinatal antibiotic exposure is associated with significant changes in the neonatal gut microbiota, potentially increasing the pathogenic microbiota"
- Michael Harrop
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- Michael Harrop
Probiotics
Probiotics Can Help or Hinder Gut Recovery After Antibiotic Treatment (Jul 2025, mice) Differential modulation of post-antibiotic colonization resistance to Clostridioides difficile by two probiotic Lactobacillus strains
- Michael Harrop
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- Michael Harrop
Testing
Blood Test Spots Early Cancer with 95% accuracy Using Gut Bacteria RNA (Jul 2025) Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples
- Michael Harrop
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- Michael Harrop
Review
Weedkiller ingredient banned in the UK, EU, China, but widely used in US can damage organs and gut bacteria (May 2025, review) Effect of Diquat on gut health: molecular mechanisms, toxic effects, and protective strategies
- Michael Harrop
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- Michael Harrop
FMT
Gut Microbiome rewiring via fecal transplants: Uncovering therapeutic avenues in Alzheimer’s disease models (Jul 2025, mice) FMT from AD to healthy mice induced profound memory impairment and cognitive deficits. FMT from healthy mice yielded remarkable behavioral improvements
- Michael Harrop
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- Michael Harrop
FMT
Fecal microbiota transplant as treatment for recurrent urinary tract infections: a proof-of-concept study (Jul 2025, n=22) 68.1% reduction in urinary infectious episodes, eradication of fecal colonization of urinary pathogens that were resistant to multiple antibiotics
- Michael Harrop
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- Michael Harrop
FMT
Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice (Jun 2025) "human-derived microbiota was less effective in clearing C. difficile compared to a mouse-derived microbiota"
- Michael Harrop
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- Michael Harrop
Causation
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation (Jun 2025, mice) Gut microbiota-specific T cells induce neuroinflammation through molecular mimicry
- Michael Harrop
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- Michael Harrop
Early development
U.S. Babies Are Missing a Key Gut Microbe, Fueling Allergy Risk (Jun 2025, n=412) Bifidobacterium deficit in United States infants drives prevalent gut dysbiosis
- Michael Harrop
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- Michael Harrop
Other
'Microbial Noah's Ark' ramps up to save Earth's invisible life forms (Jun 2025) The microbiota vault initiative: safeguarding Earth’s microbial heritage for future generations
- Michael Harrop
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- Michael Harrop
FMT
Preliminary Results From a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients With Mild-to-Moderate Crohn's Disease (Jun 2025, n=34) Terminated early due to futility.
- Michael Harrop
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- Michael Harrop
Causation
Causal link between gut microbiota and obsessive-compulsive disorder: A two-sample Mendelian randomization analysis (Mar 2025)
- Michael Harrop
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- Michael Harrop
FMT
Microbiota Therapeutics Program (MTP) at the University of Minnesota (Jun 2025, UMN) Donor-centric administration of the stool donor program is vital to its feasibility and patient safety
- Michael Harrop
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- Michael Harrop
Aging
Causal Analysis Between Gut Microbes, Aging Indicator, and Age-Related Disease, Involving the Discovery and Validation of Biomarkers (Apr 2025) "Gut microbiota a potential risk factor for 14 age-related diseases. Exhibit biomarker properties for disease prediction"
- Michael Harrop
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- Michael Harrop
FMT
Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection: A Randomized Controlled Trial (Jun 2025, n=104) "Clinical cure with no recurrence seen in 67% for FMT vs 61% for vancomycin. Up to 78% for FMT with additional treatment"
- Michael Harrop
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- Michael Harrop