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    Antiparasitics - Effects on the human microbiome in comparison to antibiotics and antifungals

    Follow-up from original thread posted by @Michael Harrop https://forum.humanmicrobiome.info/threads/an-anti-parasitic-medication-ivermectin-shifted-amazonian-villagers-mi.1378/ Hello, I want to continue from the previous thread because there is no proper entry in the “Interventions” section of...
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    How can I convince a doctor to give me Cholestyramine?

    Thanks for your experience. I am still doing tests for parasites and things like that to discare hidden infections, so we will see. I just rather try it to see if it helps. I don’t think my version of it will have sugar to be honest. Its only sold by the government and hospitals in here, so I...
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    How can I convince a doctor to give me Cholestyramine?

    Thanks Michael. His secretary is pretty trash so I will move on from him anyways. I will make sure to be more prepared next time I see a doctor.
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    How can I convince a doctor to give me Cholestyramine?

    Oh man, I just came from an appointment with a neuroGI that looks around 30ish, he told me he would rather treat SIBO (made the mistake of being honest and telling him) first and then give me CSM if it recurs. At least he is already familiar with BAM without surgery being misdiagnosed as IBS...
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    How can I convince a doctor to give me Cholestyramine?

    So I suspect I have BAM caused by dysbiosis in the terminal ileum (now causing dysbiosis everywhere). The issue is finding a doctor that will give me a CSM script. My country already has an issue with shortages of this drug, so that may be a role in their hesitation (but none actually say it...
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    FMT Exploring factors influencing university students' participation in fecal microbiota donation: a descriptive qualitative study (Aug 2026, n=30, China)

    My theory is that Chinese microbiology academia is influenced by Western microbiology academia, which is controlled and corrupted by capitalism and it’s oligarchs, and was also historically tied to Western ideals and power. So, because of the need to be taken seriously by the rest of the...
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    FMT A simulation of 2,548 gut transplants identified two “super donors” with near-universal colonization success (Sep 2026, multiple models) Metagenome-scale modeling to assess microbiome metabolic complementarity for precision microbiota transplantation therapies

    https://www.tandfonline.com/doi/full/10.1080/19490976.2026.2725403 https://biomesci.com/gut-microbiome-super-donor-fmt-metabolic-model/ Many things here about donor quality and matching that @Michael Harrop already has hypothesized and attested to anecdotally. But to me the biggest takeaway...
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    FMT Exploring factors influencing university students' participation in fecal microbiota donation: a descriptive qualitative study (Aug 2026, n=30, China)

    If that is already an issue with the lesser exhaustive screening most sources do (possibly including the study authors too), then it just proves how much of a feat it was that HM managed to find good donors with the most strict screening in the world while lacking 1% of the resources of a major...
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    Now you are making sense. Considering how many researchers downplay the lack of high quality FMT issue despite Michael reaching out, this sort of thing won’t happen until the researchers are more confident about it (unlikely) and physicians actually start listening to them. Sadly, these two...
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    Donors Can you predict if a donor is better for bile acid metabolism (BAM) during screening?

    I am taking Glutamine for that. Otherwise, I understand it needs time to recover. But it has been 6 months now. Long time for it to heal. Mmm unless I take Cholestyramine to see if that aids the “healing” by manually reabsorbing the acids.
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    Donors Can you predict if a donor is better for bile acid metabolism (BAM) during screening?

    Say which then. If you will say something like GERD or SIBO (I know what is said about it in this wiki), both of these can be caused by dysbiosis-BAM. Liver, pancreas and gallbladder are all okay, along with bloodwork. Had a CT scan during active Campylobacter infection when all of this...
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    General health “Human progress” shouldn’t have happened: discussion on how civilization advancement has made us sicker and pathogenic to the world.

    Danger from pathogens and predators and climate is higher, but I am pretty sure quality of life (for their standards) is higher. Advanced civilizations overrate long life. Example: What is the point of living for 60 years thanks to modern medicine with ME/CFS? Yes, a patient would have a normal...
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    It is easy to get into this bias when you first learn about the microbiome. Genetics is as important. Otherwise, breeding with your cousin wouldn’t have consequences.
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    Off-topic, but when the concept of “microbiome diversity decline” becomes clearer to the physician world in the future, to the point they can no longer ignore it’s main role behind the prevalence of chronic illnesses and their increasing difficulty to treat, we will already have a new population...
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    Other What is the public perception of FMT? How much does it matter? Has it been blocking progress?

    RIP Dr. Borody.
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    Procedure Washed Microbiota Transplant from China (SMT - selective microbiota transplantation)

    No, I meant you shot down WMT as a viable alternative to high-quality FMT because of the reasons you mentioned in previous threads (my comment was more like a recap for new readers or lurkers reading this thread for the first time).
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    Procedure Washed Microbiota Transplant from China (SMT - selective microbiota transplantation)

    Ignoring the whole cafe comment, I don’t think WMT will do that to him anyways. I made this comment originally citing a WMT study but I found you already addressed it in another thread, but because of how specialized the process is, how it wasn’t something feasible for HM back when it was...
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    Donors Can you predict if a donor is better for bile acid metabolism (BAM) during screening?

    Yeah, I have read everything about Michael: this whole forum, wiki and even his blogs unrelated to FMT, so I already know the answer to my question but I felt the itch to reach out anyways. Michael is a man ahead of his time. It’s a shame how most people can’t be open-minded enough to hear him...
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    I think this is a better strategy. Anyhow, we talked and I told her that I made up my mind about refusing biological children regardless of what she wants. If we break up in the future due to this, we will have to see. Even if we both do FMT, child might not have a good life because- This sort...
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    General health “Human progress” shouldn’t have happened: discussion on how civilization advancement has made us sicker and pathogenic to the world.

    https://maximiliankohler.medium.com/a-critical-look-at-the-current-and-longstanding-ethos-of-childbearing-the-repercussions-its-been-6e37f7f7b13f#02b1 https://maximiliankohler.medium.com/eugenics-past-present-and-future-74d0ea5998b4 I have been a regular member and reader of this forum and its...
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    Donors Can you predict if a donor is better for bile acid metabolism (BAM) during screening?

    Forgot about your stance. Anyhow, its always about donor quality in the end (and I did read that some studies hypothesize that any FMT success comes down to how much the donor can affect the BAM of a recipient anyways).
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    Donors Can you predict if a donor is better for bile acid metabolism (BAM) during screening?

    This may seen redundant considering what is known about donor quality (better quality = more chance of curing anything). But are there certain hints or green flags that may predict if a donor is good at certain things? In this case, fixing bile acid malabsorption (BAM) caused by dysbiosis? For...
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    FMT Only 4.7% of apparent FMT colonization events involve actual donor strain replacement (Aug 2026, n=13) Strain-level ecological filtering governs microbial colonization of the human gut

    https://biomesci.com/fmt-strain-level-colonization-cell-reports/ https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00853-3
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    Video Is SIBO real? SIBO vs dysbiosis? Debunking the SIBO hypothesis | Small Intestinal Bacterial Overgrowth

    Hi. So, I was reviewing the SIBO entry on the wiki, specifically the “Motility” section. The entry argues against the idea that SIBO is mainly caused by impaired motility, specifically the MMC. But there are other sources arguing that impaired motility can also be things like hypochloridia or...
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    Causation Three Gut Bacteria Spread Autoimmunity Between Mice With No Antibiotics Needed (July 2026, mice) Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity

    https://www.nature.com/articles/s41590-026-02599-z https://biomesci.com/gut-bacteria-autoimmunity-mice-dendritic-cells/
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    FMT A mushroom-fed faecal transplant undid antibiotic gut damage in mice (July 2026, mice) Agrocybe cylindracea polysaccharides and polysaccharides-conditioned fecal microbiota transplantation similarly restore ciprofloxacin-induced microbial dysbiosis and improve intestinal barrier function

    https://biomesci.com/agrocybe-polysaccharide-fmt-antibiotic-dysbiosis-mice/ https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1841989/full
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    Donors FMT Using Animal Feces; FMT from animals

    Are there any studies or hypothesis in current literature about the possible impact of doing FMT from apes as donors? I can only theorize and hypothesize with my current knowledge, that it would be detrimental. I assume that our microbiomes are vastly different to apes specifically because we...
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    Vagina Most Healthy Women Lack the Lactobacillus-Dominant Cervical Microbiome (July, 2026, n=92) Multi-kingdom cervical microbiome structure in health and dysbiosis: a cross-sectional study from Kazakhstan

    https://biomesci.com/cervical-microbiome-lactobacillus-normal-variation-study/ https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2026.1836889/full
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    Donors Healthy wife as donor? GI-MAP shows bacterial imbalances

    @mctopher Michael won’t explain so I will: https://humanmicrobiome.info/fmt/#screening Your wife has pre-dysbiosis gut, like most people. It doesn’t mean that it is healthy, it just means it’s not severe enough to cause problems. That means that it will either have no major effect or it would...
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    Donors Healthy wife as donor? GI-MAP shows bacterial imbalances

    Does that mean its safe for him or pointless? I mean, not everyone is looking for a superdonor like Michael, so if that is safe is enough for OP, it may be worth it.
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    Sources Is HumanMicrobes.org legit? Is it a scam? Are they really paying $500 for stool donation? Misinformation & fake reviews on reddit.

    @Michael Harrop Posting here as its on-topic. I found a guy alleging he is a donor for HumanMicrobes. He alleged OpenBiome is defunct but that HM is still operating? From my search, OpenBiome did cease distribution of investigative FMT and I thought you said that you paused orders in December...
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    Welp, she wants my child, as expected. I think I will have to just deal with the fact that my kid will be more vulnerable in the future to disease than me and their grandparents and his ancestors. And all I can give them is knowledge on how to take care of him or herself. If they come out...
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    Suggestions to minimize the impact of paternal gut dysbiosis on offspring health

    So, I know this automatically makes me a contributor to climate change and all things bad, etc. But my partner wants to have a baby. She is not a woman with eubiosis, but she is not horribly unhealthy either. Only major issue is asthma. And has used antibiotics 4 times in her life. Never had...
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    Mold exposure and CIRS: theories on gut microbiome role in Chronic Inflammatory Response Syndrome

    Sorry, I wrote that incorrectly. I meant that the treatment for CIRS seems less dangerous than the one for SIBO, as it doesn’t involve antibiotics. I think given your experiences and that of many others, not even a super donor can reverse a lifetime of accumulation of biotoxins, so getting a...
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    Mold exposure and CIRS: theories on gut microbiome role in Chronic Inflammatory Response Syndrome

    So, I am making a post here because I don’t have direct contact info (and because of your stance on no longer talking about your experiences if it helps others), but what is your opinion on Chronic Inflammatory Response Syndrome (CIRS), @Michael Harrop ? I have been reading your case and you...
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    Other FMT for Chronic Urticaria and more - Seeking advice. How to know if FMT is right for me, and how to go about it?

    Michael won’t help people with individual requests because nobody has helped him maintain and restart HumanMicrobes.org. If you only care about your own FMTs, you are on your own. Good luck.
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    Other Duplicating FMT, stool donor, and microbiome projects vs solving existing barriers

    Having read your personal blog and your Reddit history and everything regarding your experiences trying to communicate with others, I at first thought like @SFBayFMT5 and @NameHere that a major issue was your communication style and personality. But even if those played a role, it absolutely...
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    Donors How can I go about finding a top tier donor in New York City ?

    @blackpilledFMT how about giving money to @Michael Harrop to fight Congress and restart operations of the more established and successful HumanMicrobes.org for donor-recipient connection instead of making your own niche website?
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    Other Duplicating FMT, stool donor, and microbiome projects vs solving existing barriers

    So, considering I haven’t heard any update of this, I assume this user’s attempt at doing the same thing as Michael has been so far unproductive. This type of arrogance is sadly more fuel for @Michael Harrop ‘s dissatisfaction with the project. Instead of offering to help him in the area of...
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    How I got off imodium/loperamide. Identify the root cause and the appropriate tool to solve it (FMT, Cholestyramine).

    What is the appropriate thread to continue?
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